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Identification of tamoxifen metabolites in human Hep G2 cell line, human liver homogenate, and patients on long-term therapy for breast cancer

Drug metabolism and disposition, 1995-03, Vol.23 (3), p.377

1995

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Analysis of phase I and phase II metabolites of tamoxifen in breast cancer patients

Drug metabolism and disposition, 1993-11, Vol.21 (6), p.1119

1993

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Metal- and Ligand-Accelerated Catalysis of the Baylis−Hillman Reaction

Journal of organic chemistry, 1998-10, Vol.63 (21), p.7183-7189

1998

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Investigation of the Mechanism of Tamoxifen-Stimulated Breast Tumor Growth With Nonisomerizable Analogues of Tamoxifen and Metabolites

JNCI : Journal of the National Cancer Institute, 1993-05, Vol.85 (10), p.806-812

1993

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The use of a thermostable signature amidase in the resolution of the bicyclic synthon ( rac)-γ-lactam

Tetrahedron, 2004-01, Vol.60 (3), p.711-716

2004

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The effect of tamoxifen and two of its non-isomerizable fixed-ring analogs on multistage rat hepatocarcinogenesis

Carcinogenesis (New York), 1996-03, Vol.17 (3), p.585-594

1996

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Structure-function relationships of hydroxylated metabolites of tamoxifen that control the proliferation of estrogen-responsive T47D breast cancer cells in vitro

Molecular pharmacology, 1990-11, Vol.38 (5), p.737-743

1990

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A Convergent Synthesis of the 11-Oxa Prostaglandin Analogue AL-12182

Journal of organic chemistry, 2005-02, Vol.70 (4), p.1227-1236

2005

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Structure-activity relationships of nonisomerizable derivatives of tamoxifen: importance of hydroxyl group and side chain positioning for biological activity

Molecular pharmacology, 1991-03, Vol.39 (3), p.421-428

1991

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Asymmetric hydrogenation of a 4,4-diaryl-3-butenoate; a novel approach to sertraline

Organic & biomolecular chemistry, 2003-04, Vol.1 (7), p.1094

2003

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Chapter 7. Aromatic compounds

Annual reports on the progress of chemistry. Section B. Organic chemistry, 1988, Vol.85, p.163

McCague, R.

1988

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Crystallization and preliminary X-ray studies on Candida cylindracea lipase

Acta crystallographica. Section D, Biological crystallography., 1997-05, Vol.53 (3), p.348-351

1997

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A mechanistic hypothesis for DNA adduct formation by tamoxifen following hepatic oxidative metabolism

Carcinogenesis (New York), 1994-03, Vol.15 (3), p.439-442

1994

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Chapter 7. Aromatic compounds

Annual reports on the progress of chemistry. Section B. Organic chemistry, 1987, Vol.84, p.157

McCague, R.

1987

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Practical radical cyclisations leading to the construction of near-stereopure quaternary carbon stereogenic centres

Chemical communications (Cambridge, England), 1998-12 (24), p.2691-2692

1998

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Chapter 7. Aromatic compounds

Annual reports on the progress of chemistry. Section B. Organic chemistry, 1986, Vol.83, p.147

McCague, R.

1986

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On the economic application of DuPHOS rhodium(I) catalysts: a comparison of COD versus NBD precatalysts

Tetrahedron letters, 2001-10, Vol.42 (42), p.7481-7483

2001

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Use of hydrolases for the synthesis of cyclic amino acids

Tetrahedron, 2004-01, Vol.60 (3), p.717-728

2004

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Synthesis of homochiral l-(S) -tert-leucine via a lipase catalysed dynamic resolution process

Tetrahedron letters, 1995-02, Vol.36 (7), p.1113-1116

1995

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Synthesis of the Potent Antiglaucoma Agent, Travoprost

Organic process research & development, 2002-03, Vol.6 (2), p.138-145

2002

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Identifying stereoisomers of the asymmetric hydrogenation catalyst [Me-BPE-Rh(COD)]+BF4

Chirality (New York, N.Y.), 2005-05, Vol.17 (4), p.177-185

2005

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First examples of metal and ligand accelerated catalysis of the Baylis–Hillman reaction

Chemical communications (Cambridge, England), 1996 (24), p.2713-2714

1996

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An efficient stereoselective synthesis of Z-(2 S)- and Z-(2 R)-2- tert-butoxycarbonylamino-6-hydroxyhex-4-enoic acid, key intermediates in the synthesis of (2 S,4 S,5 R)-(−)- and (2 R,4 R,5 S)-(+)-bulgecinine

Tetrahedron letters, 2002-02, Vol.43 (8), p.1545-1548

2002

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A thermostable L-aminoacylase from Thermococcus litoralis: cloning, overexpression, characterization, and applications in biotransformations

Extremophiles : life under extreme conditions, 2002-04, Vol.6 (2), p.111-122

2002

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Esters of 3-pyridylacetic acid that combine potent inhibition of 17α-hydroxylase/C17,20-lyase (cytochrome P45017α) with resistance to esterase hydrolysis

Journal of medicinal chemistry, 1995-10, Vol.38 (21), p.4191-4197

1995

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Identification of tamoxifen metabolites in human Hep G2 cell line, human liver homogenate, and patients on long-term therapy for breast cancer

Analysis of phase I and phase II metabolites of tamoxifen in breast cancer patients

Metal- and Ligand-Accelerated Catalysis of the Baylis−Hillman Reaction

Investigation of the Mechanism of Tamoxifen-Stimulated Breast Tumor Growth With Nonisomerizable Analogues of Tamoxifen and Metabolites

The use of a thermostable signature amidase in the resolution of the bicyclic synthon ( rac)-γ-lactam

The effect of tamoxifen and two of its non-isomerizable fixed-ring analogs on multistage rat hepatocarcinogenesis

Structure-function relationships of hydroxylated metabolites of tamoxifen that control the proliferation of estrogen-responsive T47D breast cancer cells in vitro

A Convergent Synthesis of the 11-Oxa Prostaglandin Analogue AL-12182

Structure-activity relationships of nonisomerizable derivatives of tamoxifen: importance of hydroxyl group and side chain positioning for biological activity

Asymmetric hydrogenation of a 4,4-diaryl-3-butenoate; a novel approach to sertraline

Chapter 7. Aromatic compounds

Crystallization and preliminary X-ray studies on Candida cylindracea lipase

A mechanistic hypothesis for DNA adduct formation by tamoxifen following hepatic oxidative metabolism

Chapter 7. Aromatic compounds

Practical radical cyclisations leading to the construction of near-stereopure quaternary carbon stereogenic centres

Chapter 7. Aromatic compounds

On the economic application of DuPHOS rhodium(I) catalysts: a comparison of COD versus NBD precatalysts

Use of hydrolases for the synthesis of cyclic amino acids

Synthesis of homochiral l-(S) -tert-leucine via a lipase catalysed dynamic resolution process

Synthesis of the Potent Antiglaucoma Agent, Travoprost

Identifying stereoisomers of the asymmetric hydrogenation catalyst [Me-BPE-Rh(COD)]+BF4

First examples of metal and ligand accelerated catalysis of the Baylis–Hillman reaction

An efficient stereoselective synthesis of Z-(2 S)- and Z-(2 R)-2- tert-butoxycarbonylamino-6-hydroxyhex-4-enoic acid, key intermediates in the synthesis of (2 S,4 S,5 R)-(−)- and (2 R,4 R,5 S)-(+)-bulgecinine

A thermostable L-aminoacylase from Thermococcus litoralis: cloning, overexpression, characterization, and applications in biotransformations

Esters of 3-pyridylacetic acid that combine potent inhibition of 17α-hydroxylase/C17,20-lyase (cytochrome P45017α) with resistance to esterase hydrolysis

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