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Clinical Trials for Personalized Medicine: Design and Data Analysis

Japanese Journal of Biometrics, 2022, Vol.43(1), pp.97-119

Matsui, Shigeyuki

2022

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Blinded sample size re‐estimation for comparing over‐dispersed count data incorporating follow‐up lengths

Statistics in medicine, 2022-12, Vol.41 (29), p.5622-5644

2022

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Bias correction based on weighted likelihood for conditional estimation of subgroup effects in randomized clinical trials

Statistics in medicine, 2022-11, Vol.41 (26), p.5276-5289

2022

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Biomarker-Stratified Phase III Clinical Trials: Enhancement with a Subgroup-Focused Sequential Design

Clinical cancer research, 2018-03, Vol.24 (5), p.994-1001

2018

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Effect of Administration of Ramelteon, a Melatonin Receptor Agonist, on the Duration of Stay in the ICU: A Single-Center Randomized Placebo-Controlled Trial

Critical care medicine, 2018-07, Vol.46 (7), p.1099-1105

2018

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Outcome Related to Level of Targeted Temperature Management in Postcardiac Arrest Syndrome of Low, Moderate, and High Severities: A Nationwide Multicenter Prospective Registry

Critical care medicine, 2021-08, Vol.49 (8), p.e741

2021

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compound.Cox: Univariate feature selection and compound covariate for predicting survival

Computer methods and programs in biomedicine, 2019-01, Vol.168, p.21-37

2019

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Prospective Multicenter Study on the Prognostic and Predictive Impact of Tumor Budding in Stage II Colon Cancer: Results From the SACURA Trial

Journal of clinical oncology, 2019-08, Vol.37 (22), p.1886-1894

2019

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Dynamic Risk Prediction via a Joint Frailty-Copula Model and IPD Meta-Analysis: Building Web Applications

Entropy (Basel, Switzerland), 2022-04, Vol.24 (5), p.589

2022

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Semi-parametric empirical Bayes factor for genome-wide association studies

European journal of human genetics : EJHG, 2021-05, Vol.29 (5), p.800-807

2021

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Personalized dynamic prediction of death according to tumour progression and high-dimensional genetic factors: Meta-analysis with a joint model

Statistical methods in medical research, 2018-09, Vol.27 (9), p.2842-2858

2018

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Genomic Biomarkers for Personalized Medicine: Development and Validation in Clinical Studies

Computational and mathematical methods in medicine, 2013-01, Vol.2013, p.865980-9

2013

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A Dose-Response Meta-analysis of Coffee Consumption and Colorectal Cancer Risk in the Japanese Population: Application of a Cubic-Spline Model

Journal of epidemiology, 2018-12, Vol.28 (12), p.503-509

2018

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Relative platelet reductions provide better pathophysiologic signatures of coagulopathies in sepsis

Scientific reports, 2021-07, Vol.11 (1), p.14033-14033, Article 14033

2021

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Association Between Photoreceptor Regeneration and Visual Acuity Following Surgery for Rhegmatogenous Retinal Detachment

Investigative ophthalmology & visual science, 2016-03, Vol.57 (3), p.889-898

2016

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A large-scale multi-institutional study evaluating prognostic aspects of positive ascites cytology and effects of therapeutic interventions in epithelial ovarian cancer

Scientific reports, 2021-07, Vol.11 (1), p.15154-15154, Article 15154

2021

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Diagnosis of central diabetes insipidus using a vasopressin radioimmunoassay during hypertonic saline infusion

Endocrine Journal, 2020, Vol.67(3), pp.267-274

2020

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Desmoid with biweekly methotrexate and vinblastine shows similar effects to weekly administration: A phase II clinical trial

Cancer science, 2020-11, Vol.111 (11), p.4187-4194

2020

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Clinical Trials Express: Fracture Risk Reduction With Denosumab in Japanese Postmenopausal Women and Men With Osteoporosis: Denosumab Fracture Intervention Randomized Placebo Controlled Trial (DIRECT)

The journal of clinical endocrinology and metabolism, 2014-07, Vol.99 (7), p.2599-2607

2014

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Postoperative stroke and neurological outcomes in the early phase after revascularization surgeries for moyamoya disease: an age-stratified comparative analysis

Neurosurgical review, 2021-10, Vol.44 (5), p.2785-2795

2021

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Sample Size for Successful Genome-Wide Association Study of Major Depressive Disorder

Frontiers in genetics, 2018-06, Vol.9, p.227-227

2018

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Clinical impact of visually assessed right ventricular dysfunction in patients with septic shock

Scientific reports, 2021-09, Vol.11 (1), p.18823-18823, Article 18823

2021

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Risk factors for antibiotic resistance in hospital-acquired and ventilator-associated pneumonia

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2022-06, Vol.28 (6), p.745-752

2022

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Identifying Subgroups with Differential Responses to Amiodarone among Cardiac Arrest Patients with a Shockable Rhythm at Hospital Arrival using the Machine Learning Approach

Reviews in cardiovascular medicine, 2024-07, Vol.25 (7), p.268

2024

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Clinical Trials for Personalized Medicine: Design and Data Analysis

Blinded sample size re‐estimation for comparing over‐dispersed count data incorporating follow‐up lengths

Bias correction based on weighted likelihood for conditional estimation of subgroup effects in randomized clinical trials

Biomarker-Stratified Phase III Clinical Trials: Enhancement with a Subgroup-Focused Sequential Design

Effect of Administration of Ramelteon, a Melatonin Receptor Agonist, on the Duration of Stay in the ICU: A Single-Center Randomized Placebo-Controlled Trial

The PD-1 expression balance between effector and regulatory T cells predicts the clinical efficacy of PD-1 blockade therapies

Outcome Related to Level of Targeted Temperature Management in Postcardiac Arrest Syndrome of Low, Moderate, and High Severities: A Nationwide Multicenter Prospective Registry

compound.Cox: Univariate feature selection and compound covariate for predicting survival

Prospective Multicenter Study on the Prognostic and Predictive Impact of Tumor Budding in Stage II Colon Cancer: Results From the SACURA Trial

Dynamic Risk Prediction via a Joint Frailty-Copula Model and IPD Meta-Analysis: Building Web Applications

Semi-parametric empirical Bayes factor for genome-wide association studies

Personalized dynamic prediction of death according to tumour progression and high-dimensional genetic factors: Meta-analysis with a joint model

Genomic Biomarkers for Personalized Medicine: Development and Validation in Clinical Studies

A Dose-Response Meta-analysis of Coffee Consumption and Colorectal Cancer Risk in the Japanese Population: Application of a Cubic-Spline Model

Relative platelet reductions provide better pathophysiologic signatures of coagulopathies in sepsis

Association Between Photoreceptor Regeneration and Visual Acuity Following Surgery for Rhegmatogenous Retinal Detachment

A large-scale multi-institutional study evaluating prognostic aspects of positive ascites cytology and effects of therapeutic interventions in epithelial ovarian cancer

Diagnosis of central diabetes insipidus using a vasopressin radioimmunoassay during hypertonic saline infusion

Desmoid with biweekly methotrexate and vinblastine shows similar effects to weekly administration: A phase II clinical trial

Clinical Trials Express: Fracture Risk Reduction With Denosumab in Japanese Postmenopausal Women and Men With Osteoporosis: Denosumab Fracture Intervention Randomized Placebo Controlled Trial (DIRECT)

Postoperative stroke and neurological outcomes in the early phase after revascularization surgeries for moyamoya disease: an age-stratified comparative analysis

Sample Size for Successful Genome-Wide Association Study of Major Depressive Disorder

Clinical impact of visually assessed right ventricular dysfunction in patients with septic shock

Risk factors for antibiotic resistance in hospital-acquired and ventilator-associated pneumonia

Identifying Subgroups with Differential Responses to Amiodarone among Cardiac Arrest Patients with a Shockable Rhythm at Hospital Arrival using the Machine Learning Approach

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