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ALDH1A3‐mTOR axis as a therapeutic target for anticancer drug‐tolerant persister cells in gastric cancer

Cancer science, 2020-03, Vol.111 (3), p.962-973

2020

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APC Mutations as a Potential Biomarker for Sensitivity to Tankyrase Inhibitors in Colorectal Cancer

Molecular cancer therapeutics, 2017-04, Vol.16 (4), p.752-762

2017

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Neutralization of the induced VEGF-A potentiates the therapeutic effect of an anti-VEGFR2 antibody on gastric cancer in vivo

Scientific reports, 2021-07, Vol.11 (1), p.15125-15125, Article 15125

2021

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Tankyrase Inhibitors Target Colorectal Cancer Stem Cells via AXIN-Dependent Downregulation of c-KIT Tyrosine Kinase

Molecular cancer therapeutics, 2020-03, Vol.19 (3), p.765-776

2020

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Molecular targeting therapy of cancer: drug resistance, apoptosis and survival signal

Cancer science, 2003-01, Vol.94 (1), p.15-21

2003

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c-KIT regulates stability of cancer stemness in CD44-positive colorectal cancer cells

Biochemical and biophysical research communications, 2020-07, Vol.527 (4), p.1014-1020

2020

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Lamellarin 14, a derivative of marine alkaloids, inhibits the T790M/C797S mutant epidermal growth factor receptor

Cancer science, 2021-05, Vol.112 (5), p.1963-1974

2021

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ATP citrate lyase: activation and therapeutic implications in non-small cell lung cancer

Cancer research (Chicago, Ill.), 2008-10, Vol.68 (20), p.8547-8554

2008

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In silico chemical screening identifies epidermal growth factor receptor as a therapeutic target of drug-tolerant CD44v9-positive gastric cancer cells

British journal of cancer, 2019-11, Vol.121 (10), p.846-856

2019

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Epidermal growth factor receptor mRNA expression: A potential molecular escape mechanism from regorafenib

Cancer science, 2020-02, Vol.111 (2), p.441-450

2020

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Acyl‐CoA synthetase as a cancer survival factor: its inhibition enhances the efficacy of etoposide

Cancer science, 2009-08, Vol.100 (8), p.1556-1562

2009

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TRIB1 Supports Prostate Tumorigenesis and Tumor-Propagating Cell Survival by Regulation of Endoplasmic Reticulum Chaperone Expression

Cancer research (Chicago, Ill.), 2014-09, Vol.74 (17), p.4888-4897

2014

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Phase II trial of biweekly cetuximab and irinotecan as third‐line therapy for pretreated KRAS exon 2 wild‐type colorectal cancer

Cancer science, 2018-08, Vol.109 (8), p.2567-2575

2018

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Pharmacological targeting of constitutively active truncated androgen receptor by nigericin and suppression of hormone-refractory prostate cancer cell growth

Molecular pharmacology, 2010-11, Vol.78 (5), p.846-854

2010

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Comprehensive transcriptomic analysis of molecularly targeted drugs in cancer for target pathway evaluation

Cancer science, 2015-07, Vol.106 (7), p.909-920

2015

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A phase I study to determine the maximum tolerated dose of trifluridine/tipiracil and oxaliplatin in patients with refractory metastatic colorectal cancer: LUPIN study

Investigational new drugs, 2020-02, Vol.38 (1), p.111-119

2020

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Defects of the apoptotic pathway as therapeutic target against cancer

Drug resistance updates, 2005-12, Vol.8 (6), p.339-343

2005

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mTOR signaling mediates resistance to tankyrase inhibitors in Wnt-driven colorectal cancer

Oncotarget, 2017-07, Vol.8 (29), p.47902-47915

2017

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Identification of ATF-3, caveolin-1, DLC-1, and NM23-H2 as putative antitumorigenic, progesterone-regulated genes for ovarian cancer cells by gene profiling

Oncogene, 2005-03, Vol.24 (10), p.1774-1787

2005

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Caspase-mediated cleavage of cytoskeletal actin plays a positive role in the process of morphological apoptosis

Oncogene, 1999-04, Vol.18 (15), p.2423-2430

1999

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Potential Molecular Cross Talk Among CCR5 Pathway Predicts Regorafenib Responsiveness in Metastatic Colorectal Cancer Patients

Cancer genomics & proteomics, 2021-05, Vol.18 (3), p.317-324

2021

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Modulation of Heat-shock Protein 27 (Hsp27) Anti-apoptotic Activity by Methylglyoxal Modification

The Journal of biological chemistry, 2002-11, Vol.277 (48), p.45770-45775

2002

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Meeting report of the 14th Japan–Korea joint symposium on cancer and aging research: current status of translational research and approaches to precision medicine

Journal of cancer research and clinical oncology, 2019-05, Vol.145 (5), p.1263-1271

2019

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Development of a gene expression database and related analysis programs for evaluation of anticancer compounds

Cancer science, 2013-03, Vol.104 (3), p.360-368

2013

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Cancer Stem Cells (CSCs) as a Rational Therapeutic Cancer Target, and Screening for CSC-targeting Drugs

YAKUGAKU ZASSHI, 2017/02/01, Vol.137(2), pp.129-132

Mashima, Tetsuo

2017

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ALDH1A3‐mTOR axis as a therapeutic target for anticancer drug‐tolerant persister cells in gastric cancer

APC Mutations as a Potential Biomarker for Sensitivity to Tankyrase Inhibitors in Colorectal Cancer

Neutralization of the induced VEGF-A potentiates the therapeutic effect of an anti-VEGFR2 antibody on gastric cancer in vivo

Tankyrase Inhibitors Target Colorectal Cancer Stem Cells via AXIN-Dependent Downregulation of c-KIT Tyrosine Kinase

Molecular targeting therapy of cancer: drug resistance, apoptosis and survival signal

c-KIT regulates stability of cancer stemness in CD44-positive colorectal cancer cells

Lamellarin 14, a derivative of marine alkaloids, inhibits the T790M/C797S mutant epidermal growth factor receptor

ATP citrate lyase: activation and therapeutic implications in non-small cell lung cancer

In silico chemical screening identifies epidermal growth factor receptor as a therapeutic target of drug-tolerant CD44v9-positive gastric cancer cells

Epidermal growth factor receptor mRNA expression: A potential molecular escape mechanism from regorafenib

Acyl‐CoA synthetase as a cancer survival factor: its inhibition enhances the efficacy of etoposide

TRIB1 Supports Prostate Tumorigenesis and Tumor-Propagating Cell Survival by Regulation of Endoplasmic Reticulum Chaperone Expression

Phase II trial of biweekly cetuximab and irinotecan as third‐line therapy for pretreated KRAS exon 2 wild‐type colorectal cancer

Pharmacological targeting of constitutively active truncated androgen receptor by nigericin and suppression of hormone-refractory prostate cancer cell growth

Comprehensive transcriptomic analysis of molecularly targeted drugs in cancer for target pathway evaluation

A phase I study to determine the maximum tolerated dose of trifluridine/tipiracil and oxaliplatin in patients with refractory metastatic colorectal cancer: LUPIN study

Defects of the apoptotic pathway as therapeutic target against cancer

mTOR signaling mediates resistance to tankyrase inhibitors in Wnt-driven colorectal cancer

Identification of ATF-3, caveolin-1, DLC-1, and NM23-H2 as putative antitumorigenic, progesterone-regulated genes for ovarian cancer cells by gene profiling

Caspase-mediated cleavage of cytoskeletal actin plays a positive role in the process of morphological apoptosis

Potential Molecular Cross Talk Among CCR5 Pathway Predicts Regorafenib Responsiveness in Metastatic Colorectal Cancer Patients

Modulation of Heat-shock Protein 27 (Hsp27) Anti-apoptotic Activity by Methylglyoxal Modification

Meeting report of the 14th Japan–Korea joint symposium on cancer and aging research: current status of translational research and approaches to precision medicine

Development of a gene expression database and related analysis programs for evaluation of anticancer compounds

Cancer Stem Cells (CSCs) as a Rational Therapeutic Cancer Target, and Screening for CSC-targeting Drugs

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