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The T cell receptor repertoire of tumor infiltrating T cells is predictive and prognostic for cancer survival

Nature communications, 2021-07, Vol.12 (1), p.4098-4098, Article 4098

2021

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Kinase-Dead BRAF and Oncogenic RAS Cooperate to Drive Tumor Progression through CRAF

Cell, 2010-01, Vol.140 (2), p.209-221

2010

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Inhibiting Drivers of Non-mutational Drug Tolerance Is a Salvage Strategy for Targeted Melanoma Therapy

Cancer cell, 2016-03, Vol.29 (3), p.270-284

2016

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ROCK and JAK1 Signaling Cooperate to Control Actomyosin Contractility in Tumor Cells and Stroma

Cancer cell, 2011-08, Vol.20 (2), p.229-245

2011

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Application of Sequencing, Liquid Biopsies, and Patient-Derived Xenografts for Personalized Medicine in Melanoma

Cancer discovery, 2016-03, Vol.6 (3), p.286-299

2016

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Oncogenic BRAF regulates melanoma proliferation through the lineage specific factor MITF

PloS one, 2008-07, Vol.3 (7), p.e2734-e2734

2008

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Inhibiting EGF receptor or SRC family kinase signaling overcomes BRAF inhibitor resistance in melanoma

Cancer discovery, 2013-02, Vol.3 (2), p.158-167

2013

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BRAF Signaling and Targeted Therapies in Melanoma

Hematology/oncology clinics of North America, 2009-06, Vol.23 (3), p.529-545

2009

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Elevated expression of MITF counteracts B-RAF-stimulated melanocyte and melanoma cell proliferation

The Journal of cell biology, 2005-08, Vol.170 (5), p.703-708

2005

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Lysyl oxidase drives tumour progression by trapping EGF receptors at the cell surface

Nature communications, 2017-04, Vol.8 (1), p.14909-14909, Article 14909

2017

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Wild-Type and Mutant B-RAF Activate C-RAF through Distinct Mechanisms Involving Heterodimerization

Molecular cell, 2005-12, Vol.20 (6), p.963-969

2005

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Resistance to BRAF inhibitors induces glutamine dependency in melanoma cells

Molecular oncology, 2016-01, Vol.10 (1), p.73-84

2016

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Functional classification of DDOST variants of uncertain clinical significance in congenital disorders of glycosylation

Scientific reports, 2023-10, Vol.13 (1), p.17648-17648, Article 17648

2023

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Protein Kinase A Blocks Raf-1 Activity by Stimulating 14-3-3 Binding and Blocking Raf-1 Interaction with Ras

The Journal of biological chemistry, 2003-08, Vol.278 (32), p.29819-29823

2003

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Intravital Imaging Reveals Transient Changes in Pigment Production and Brn2 Expression during Metastatic Melanoma Dissemination

Cancer research (Chicago, Ill.), 2009-10, Vol.69 (20), p.7969-7977

2009

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Targeting the LOX/hypoxia axis reverses many of the features that make pancreatic cancer deadly: inhibition of LOX abrogates metastasis and enhances drug efficacy

EMBO molecular medicine, 2015-08, Vol.7 (8), p.1063-1076

2015

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Ultraviolet radiation drives mutations in a subset of mucosal melanomas

Nature communications, 2021-01, Vol.12 (1), p.259-7, Article 259

2021

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Elucidating distinct roles for NF1 in melanomagenesis

Cancer discovery, 2013-03, Vol.3 (3), p.338-349

2013

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Anti-metastatic Inhibitors of Lysyl Oxidase (LOX): Design and Structure–Activity Relationships

Journal of medicinal chemistry, 2019-06, Vol.62 (12), p.5863-5884

2019

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Deja Vu: EGF receptors drive resistance to BRAF inhibitors

Cancer discovery, 2013-05, Vol.3 (5), p.487-490

2013

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Analysis of the efficacy and toxicity of sorafenib in thyroid cancer: a phase II study in a UK based population

European journal of endocrinology, 2011-08, Vol.165 (2), p.315-322

2011

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The mutational burden of acral melanoma revealed by whole-genome sequencing and comparative analysis

Pigment cell and melanoma research, 2014-09, Vol.27 (5), p.835-838

2014

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The Changing Epidemiology of Desmoplastic Melanoma

Acta dermato-venereologica, 2023-01, Vol.103, p.adv00852-adv00852

2023

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Inactivation of TGFβ receptors in stem cells drives cutaneous squamous cell carcinoma

Nature communications, 2016-08, Vol.7 (1), p.12493-14, Article 12493

2016

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Mechanism of Activation of the RAF-ERK Signaling Pathway by Oncogenic Mutations of B-RAF

Cell, 2004-03, Vol.116 (6), p.855-867

2004

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The T cell receptor repertoire of tumor infiltrating T cells is predictive and prognostic for cancer survival

Kinase-Dead BRAF and Oncogenic RAS Cooperate to Drive Tumor Progression through CRAF

Inhibiting Drivers of Non-mutational Drug Tolerance Is a Salvage Strategy for Targeted Melanoma Therapy

ROCK and JAK1 Signaling Cooperate to Control Actomyosin Contractility in Tumor Cells and Stroma

Application of Sequencing, Liquid Biopsies, and Patient-Derived Xenografts for Personalized Medicine in Melanoma

Oncogenic BRAF regulates melanoma proliferation through the lineage specific factor MITF

Inhibiting EGF receptor or SRC family kinase signaling overcomes BRAF inhibitor resistance in melanoma

BRAF Signaling and Targeted Therapies in Melanoma

Elevated expression of MITF counteracts B-RAF-stimulated melanocyte and melanoma cell proliferation

Lysyl oxidase drives tumour progression by trapping EGF receptors at the cell surface

Wild-Type and Mutant B-RAF Activate C-RAF through Distinct Mechanisms Involving Heterodimerization

Resistance to BRAF inhibitors induces glutamine dependency in melanoma cells

Functional classification of DDOST variants of uncertain clinical significance in congenital disorders of glycosylation

Protein Kinase A Blocks Raf-1 Activity by Stimulating 14-3-3 Binding and Blocking Raf-1 Interaction with Ras

Intravital Imaging Reveals Transient Changes in Pigment Production and Brn2 Expression during Metastatic Melanoma Dissemination

Targeting the LOX/hypoxia axis reverses many of the features that make pancreatic cancer deadly: inhibition of LOX abrogates metastasis and enhances drug efficacy

Ultraviolet radiation drives mutations in a subset of mucosal melanomas

Elucidating distinct roles for NF1 in melanomagenesis

Anti-metastatic Inhibitors of Lysyl Oxidase (LOX): Design and Structure–Activity Relationships

Deja Vu: EGF receptors drive resistance to BRAF inhibitors

Analysis of the efficacy and toxicity of sorafenib in thyroid cancer: a phase II study in a UK based population

The mutational burden of acral melanoma revealed by whole-genome sequencing and comparative analysis

The Changing Epidemiology of Desmoplastic Melanoma

Inactivation of TGFβ receptors in stem cells drives cutaneous squamous cell carcinoma

Mechanism of Activation of the RAF-ERK Signaling Pathway by Oncogenic Mutations of B-RAF

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