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Preservation of forelimb function by UPF1 gene therapy in a rat model of TDP-43-induced motor paralysis

Gene therapy, 2015-01, Vol.22 (1), p.20-28

2015

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Defects in RNA splicing and the consequence of shortened translational reading frames

American journal of human genetics, 1996-08, Vol.59 (2), p.279-286

MAQUAT, L. E

1996

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When cells stop making sense: effects of nonsense codons on RNA metabolism in vertebrate cells

RNA (Cambridge), 1995-07, Vol.1 (5), p.453-465

Maquat, L E

1995

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CBP80-promoted mRNP rearrangements during the pioneer round of translation, nonsense-mediated mRNA decay, and thereafter

Cold Spring Harbor Symposia on Quantitative Biology, 2010, Vol.75, p.127-134

2010

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Identification and Characterization of Human Orthologues to Saccharomyces cerevisiae Upf2 Protein and Upf3 Protein (Caenorhabditis elegans SMG-4)

Molecular and Cellular Biology, 2001-01, Vol.21 (1), p.209-223

2001

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Mammalian heat shock p70 and histone H4 transcripts, which derive from naturally intronless genes, are immune to nonsense-mediated decay

RNA (Cambridge), 2001-03, Vol.7 (3), p.445-456, Article S1355838201002229

2001

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A rule for termination-codon position within intron-containing genes: when nonsense affects RNA abundance

Trends in biochemical sciences (Amsterdam. Regular ed.), 1998-06, Vol.23 (6), p.198-199

1998

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The spliceosome deposits multiple proteins 20–24 nucleotides upstream of mRNA exon–exon junctions

The EMBO journal, 2000-12, Vol.19 (24), p.6860-6869

2000

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Evidence for a Pioneer Round of mRNA Translation: mRNAs Subject to Nonsense-Mediated Decay in Mammalian Cells Are Bound by CBP80 and CBP20

Cell, 2001-09, Vol.106 (5), p.607-617

2001

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Nonsense codons can reduce the abundance of nuclear mRNA without affecting the abundance of pre-mRNA or the half-life of cytoplasmic mRNA

Molecular and Cellular Biology, 1993-03, Vol.13 (3), p.1892-1902

1993

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Quality Control of mRNA Function

Cell, 2001-01, Vol.104 (2), p.173-176

2001

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The power of point mutations

Nature genetics, 2001-01, Vol.27 (1), p.5-6

Maquat, Lynne E

2001

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Evidence to Implicate Translation by Ribosomes in the Mechanism by which Nonsense Codons Reduce the Nuclear Level of Human Triosephosphate Isomerase mRNA

Proceedings of the National Academy of Sciences - PNAS, 1993-01, Vol.90 (2), p.482-486

1993

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Pre-mRNA splicing alters mRNP composition: evidence for stable association of proteins at exon-exon junctions

Genes & development, 2000-05, Vol.14 (9), p.1098-1108

2000

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Nonsense but not missense mutations can decrease the abundance of nuclear mRNA for the mouse major urinary protein, while both types of mutations can facilitate exon skipping

Molecular and Cellular Biology, 1994-09, Vol.14 (9), p.6326-6336

1994

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Nonsense-mediated decay of mRNA for the selenoprotein phospholipid hydroperoxide glutathione peroxidase is detectable in cultured cells but masked or inhibited in rat tissues

Molecular biology of the cell, 2001-04, Vol.12 (4), p.1009-1017

2001

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Premature translation termination mediates triosephosphate isomerase mRNA degradation

Molecular and Cellular Biology, 1988-02, Vol.8 (2), p.802-813

1988

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Sequences within the last intron function in RNA 3'-end formation in cultured cells

Molecular and Cellular Biology, 1993-06, Vol.13 (6), p.3359-3369

1993

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Translation to near the distal end of the penultimate exon is required for normal levels of spliced triosephosphate isomerase mRNA

Molecular and Cellular Biology, 1990-10, Vol.10 (10), p.5215-5225

1990

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Mammalian nonsense codons can be cis effectors of nuclear mRNA half-life

Molecular and Cellular Biology, 1994-12, Vol.14 (12), p.8219-8228

1994

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Introns are cis effectors of the nonsense-codon-mediated reduction in nuclear mRNA abundance

Molecular and Cellular Biology, 1994-09, Vol.14 (9), p.6317-6325

1994

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Upstream introns influence the efficiency of final intron removal and RNA 3'-end formation

Genes & development, 1994-02, Vol.8 (3), p.363-375

1994

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Evidence that selenium deficiency results in the cytoplasmic decay of GPx1 mRNA dependent on pre-mRNA splicing proteins bound to the mRNA exon-exon junction

BioFactors (Oxford), 2001, Vol.14 (1-4), p.37-42

Maquat, Lynne E.

2001

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Cloning of a novel phosphatidylinositol kinase-related kinase: characterization of the human SMG-1 RNA surveillance protein

The Journal of biological chemistry, 2001-06, Vol.276 (25), p.22709-22714

2001

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Nonsense-mediated mRNA decay: splicing, translation and mRNP dynamics

Nature reviews. Molecular cell biology, 2004-02, Vol.5 (2), p.89-99

Maquat, Lynne E

2004

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Preservation of forelimb function by UPF1 gene therapy in a rat model of TDP-43-induced motor paralysis

Defects in RNA splicing and the consequence of shortened translational reading frames

When cells stop making sense: effects of nonsense codons on RNA metabolism in vertebrate cells

CBP80-promoted mRNP rearrangements during the pioneer round of translation, nonsense-mediated mRNA decay, and thereafter

Identification and Characterization of Human Orthologues to Saccharomyces cerevisiae Upf2 Protein and Upf3 Protein (Caenorhabditis elegans SMG-4)

Mammalian heat shock p70 and histone H4 transcripts, which derive from naturally intronless genes, are immune to nonsense-mediated decay

A rule for termination-codon position within intron-containing genes: when nonsense affects RNA abundance

The spliceosome deposits multiple proteins 20–24 nucleotides upstream of mRNA exon–exon junctions

Evidence for a Pioneer Round of mRNA Translation: mRNAs Subject to Nonsense-Mediated Decay in Mammalian Cells Are Bound by CBP80 and CBP20

Nonsense codons can reduce the abundance of nuclear mRNA without affecting the abundance of pre-mRNA or the half-life of cytoplasmic mRNA

Quality Control of mRNA Function

The power of point mutations

Evidence to Implicate Translation by Ribosomes in the Mechanism by which Nonsense Codons Reduce the Nuclear Level of Human Triosephosphate Isomerase mRNA

Pre-mRNA splicing alters mRNP composition: evidence for stable association of proteins at exon-exon junctions

Nonsense but not missense mutations can decrease the abundance of nuclear mRNA for the mouse major urinary protein, while both types of mutations can facilitate exon skipping

Nonsense-mediated decay of mRNA for the selenoprotein phospholipid hydroperoxide glutathione peroxidase is detectable in cultured cells but masked or inhibited in rat tissues

Premature translation termination mediates triosephosphate isomerase mRNA degradation

Sequences within the last intron function in RNA 3'-end formation in cultured cells

Translation to near the distal end of the penultimate exon is required for normal levels of spliced triosephosphate isomerase mRNA

Mammalian nonsense codons can be cis effectors of nuclear mRNA half-life

Introns are cis effectors of the nonsense-codon-mediated reduction in nuclear mRNA abundance

Upstream introns influence the efficiency of final intron removal and RNA 3'-end formation

Evidence that selenium deficiency results in the cytoplasmic decay of GPx1 mRNA dependent on pre-mRNA splicing proteins bound to the mRNA exon-exon junction

Cloning of a novel phosphatidylinositol kinase-related kinase: characterization of the human SMG-1 RNA surveillance protein

Nonsense-mediated mRNA decay: splicing, translation and mRNP dynamics

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