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Chronic Elevation of Parathyroid Hormone in Mice Reduces Expression of Sclerostin by Osteocytes: A Novel Mechanism for Hormonal Control of Osteoblastogenesis

Endocrinology (Philadelphia), 2005-11, Vol.146 (11), p.4577-4583

2005

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Birth and Death of Bone Cells: Basic Regulatory Mechanisms and Implications for the Pathogenesis and Treatment of Osteoporosis

Endocrine reviews, 2000-04, Vol.21 (2), p.115-137

Manolagas, S. C.

2000

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Mechanical stimulation prevents osteocyte apoptosis: requirement of integrins, Src kinases, and ERKs

American Journal of Physiology: Cell Physiology, 2005-09, Vol.289 (3), p.C633-C643

2005

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Glucocorticoids Act Directly on Osteoclasts to Increase Their Life Span and Reduce Bone Density

Endocrinology (Philadelphia), 2006-12, Vol.147 (12), p.5592-5599

2006

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Reversal of Bone Loss in Mice by Nongenotropic Signaling of Sex Steroids

Science (American Association for the Advancement of Science), 2002-10, Vol.298 (5594), p.843-846

2002

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Glucocorticoids Act Directly on Osteoblasts and Osteocytes to Induce Their Apoptosis and Reduce Bone Formation and Strength

Endocrinology (Philadelphia), 2004-04, Vol.145 (4), p.1835-1841

2004

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New Developments in the Pathogenesis and Treatment of Steroid‐Induced Osteoporosis

Journal of bone and mineral research, 1999-07, Vol.14 (7), p.1061-1066

1999

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Apoptosis of osteocytes in glucocorticoid-induced osteonecrosis of the hip

The journal of clinical endocrinology and metabolism, 2000-08, Vol.85 (8), p.2907-2912

2000

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Inhibin Suppresses and Activin Stimulates Osteoblastogenesis and Osteoclastogenesis in Murine Bone Marrow Cultures

Endocrinology (Philadelphia), 2002-01, Vol.143 (1), p.74-83

2002

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The pathophysiologic roles of interleukin-6 in human disease

Annals of internal medicine, 1998-01, Vol.128 (2), p.127

1998

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Apoptosis and osteoporosis

The American journal of medicine, 2000-02, Vol.108 (2), p.153-164

2000

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Osteoblast Programmed Cell Death (Apoptosis): Modulation by Growth Factors and Cytokines

Journal of bone and mineral research, 1998-05, Vol.13 (5), p.793-802

1998

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Essential Requirement of BMPs‐2/4 for Both Osteoblast and Osteoclast Formation in Murine Bone Marrow Cultures from Adult Mice: Antagonism by Noggin

Journal of bone and mineral research, 2000-04, Vol.15 (4), p.663-673

2000

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Role of cytokines in bone resorption

Bone (New York, N.Y.), 1995-08, Vol.17 (2 Suppl), p.63S-S67

Manolagas, S C

1995

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Classical Genotropic Versus Kinase-Initiated Regulation of Gene Transcription by the Estrogen Receptor α

Endocrinology (Philadelphia), 2006-04, Vol.147 (4), p.1986-1996

2006

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Interleukin-11 : a new cytokine critical for osteoclast development

The Journal of clinical investigation, 1994-04, Vol.93 (4), p.1516-1524

1994

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Increased Osteoclast Development After Estrogen Loss: Mediation by Interleukin-6

Science (American Association for the Advancement of Science), 1992-07, Vol.257 (5066), p.88-91

1992

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Osteocyte Apoptosis Is Induced by Weightlessness in Mice and Precedes Osteoclast Recruitment and Bone Loss

Journal of bone and mineral research, 2006-04, Vol.21 (4), p.605-615

2006

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Regulation of interleukin-6, osteoclastogenesis, and bone mass by androgens. The role of the androgen receptor

The Journal of clinical investigation, 1995-06, Vol.95 (6), p.2886-2895

1995

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Increased Adipogenesis and Myelopoiesis in the Bone Marrow of SAMP6, a Murine Model of Defective Osteoblastogenesis and Low Turnover Osteopenia

Journal of bone and mineral research, 1997-11, Vol.12 (11), p.1772-1779

1997

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Cbfa1 does not regulate RANKL gene activity in stromal/osteoblastic cells

Bone (New York, N.Y.), 2002-03, Vol.30 (3), p.453-462

2002

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Transduction of Cell Survival Signals by Connexin-43 Hemichannels

The Journal of biological chemistry, 2002-03, Vol.277 (10), p.8648-8657

2002

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Bone Marrow, Cytokines, and Bone Remodeling — Emerging Insights into the Pathophysiology of Osteoporosis

The New England journal of medicine, 1995-02, Vol.332 (5), p.305-311

1995

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17 beta-Estradiol inhibits expression of human interleukin-6 promoter-reporter constructs by a receptor-dependent mechanism

The Journal of clinical investigation, 1994-03, Vol.93 (3), p.944-950

1994

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Proteasomal degradation of Runx2 shortens parathyroid hormone-induced anti-apoptotic signaling in osteoblasts. A putative explanation for why intermittent administration is needed for bone anabolism

The Journal of biological chemistry, 2003-12, Vol.278 (50), p.50259-50272

2003

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Chronic Elevation of Parathyroid Hormone in Mice Reduces Expression of Sclerostin by Osteocytes: A Novel Mechanism for Hormonal Control of Osteoblastogenesis

Birth and Death of Bone Cells: Basic Regulatory Mechanisms and Implications for the Pathogenesis and Treatment of Osteoporosis

Mechanical stimulation prevents osteocyte apoptosis: requirement of integrins, Src kinases, and ERKs

Glucocorticoids Act Directly on Osteoclasts to Increase Their Life Span and Reduce Bone Density

Reversal of Bone Loss in Mice by Nongenotropic Signaling of Sex Steroids

Glucocorticoids Act Directly on Osteoblasts and Osteocytes to Induce Their Apoptosis and Reduce Bone Formation and Strength

New Developments in the Pathogenesis and Treatment of Steroid‐Induced Osteoporosis

Apoptosis of osteocytes in glucocorticoid-induced osteonecrosis of the hip

Inhibin Suppresses and Activin Stimulates Osteoblastogenesis and Osteoclastogenesis in Murine Bone Marrow Cultures

The pathophysiologic roles of interleukin-6 in human disease

Apoptosis and osteoporosis

Osteoblast Programmed Cell Death (Apoptosis): Modulation by Growth Factors and Cytokines

Essential Requirement of BMPs‐2/4 for Both Osteoblast and Osteoclast Formation in Murine Bone Marrow Cultures from Adult Mice: Antagonism by Noggin

Role of cytokines in bone resorption

Classical Genotropic Versus Kinase-Initiated Regulation of Gene Transcription by the Estrogen Receptor α

Interleukin-11 : a new cytokine critical for osteoclast development

Increased Osteoclast Development After Estrogen Loss: Mediation by Interleukin-6

Osteocyte Apoptosis Is Induced by Weightlessness in Mice and Precedes Osteoclast Recruitment and Bone Loss

Regulation of interleukin-6, osteoclastogenesis, and bone mass by androgens. The role of the androgen receptor

Increased Adipogenesis and Myelopoiesis in the Bone Marrow of SAMP6, a Murine Model of Defective Osteoblastogenesis and Low Turnover Osteopenia

Cbfa1 does not regulate RANKL gene activity in stromal/osteoblastic cells

Transduction of Cell Survival Signals by Connexin-43 Hemichannels

Bone Marrow, Cytokines, and Bone Remodeling — Emerging Insights into the Pathophysiology of Osteoporosis

17 beta-Estradiol inhibits expression of human interleukin-6 promoter-reporter constructs by a receptor-dependent mechanism

Proteasomal degradation of Runx2 shortens parathyroid hormone-induced anti-apoptotic signaling in osteoblasts. A putative explanation for why intermittent administration is needed for bone anabolism

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