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Chemical Genetic Analysis and Functional Characterization of Staphylococcal Wall Teichoic Acid 2-Epimerases Reveals Unconventional Antibiotic Drug Targets

PLoS pathogens, 2016-05, Vol.12 (5), p.e1005585-e1005585

2016

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Impact of Antifungal Prophylaxis on Colonization and Azole Susceptibility of Candida Species

Antimicrobial Agents and Chemotherapy, 2009-12, Vol.53 (12), p.5026-5034

2009

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Chemical Genomics-Based Antifungal Drug Discovery: Targeting Glycosylphosphatidylinositol (GPI) Precursor Biosynthesis

ACS infectious diseases, 2015-01, Vol.1 (1), p.59-72

2015

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Multiple Resistance Mechanisms among Aspergillus fumigatus Mutants with High-Level Resistance to Itraconazole

Antimicrobial Agents and Chemotherapy, 2003-05, Vol.47 (5), p.1719-1726

2003

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Mutations in Aspergillus fumigatus Resulting in Reduced Susceptibility to Posaconazole Appear To Be Restricted to a Single Amino Acid in the Cytochrome P450 14α-Demethylase

Antimicrobial Agents and Chemotherapy, 2003-02, Vol.47 (2), p.577-581

2003

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Selective small-molecule inhibition of an RNA structural element

Nature (London), 2015-10, Vol.526 (7575), p.672-677

2015

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Mapping and characterization of vicriviroc resistance mutations from HIV-1 isolated from treatment-experienced subjects enrolled in a phase II study (VICTOR-E1)

Journal of acquired immune deficiency syndromes (1999), 2011-03, Vol.56 (3), p.222-229

2011

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Dual-Targeting Small-Molecule Inhibitors of the Staphylococcus aureus FMN Riboswitch Disrupt Riboflavin Homeostasis in an Infectious Setting

Cell chemical biology, 2017-05, Vol.24 (5), p.576-588.e6

2017

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Posaconazole Is a Potent Inhibitor of Sterol 14α-Demethylation in Yeasts and Molds

Antimicrobial Agents and Chemotherapy, 2004-10, Vol.48 (10), p.3690-3696

2004

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Molecular Basis for Enhanced Activity of Posaconazole against Absidia corymbifera and Rhizopus oryzae

Antimicrobial Agents and Chemotherapy, 2006-11, Vol.50 (11), p.3917-3919

2006

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Tectonics, basin subsidence mechanisms, and paleogeography of the Caribbean-South American plate boundary zone

Marine and petroleum geology, 2011, Vol.28 (1), p.8-39

2011

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Inhibitor of intramembrane protease RseP blocks the σE response causing lethal accumulation of unfolded outer membrane proteins

Proceedings of the National Academy of Sciences - PNAS, 2018-07, Vol.115 (28), p.E6614-E6621

2018

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Murgocil is a Highly Bioactive Staphylococcal-Specific Inhibitor of the Peptidoglycan Glycosyltransferase Enzyme MurG

ACS chemical biology, 2013-11, Vol.8 (11), p.2442-2451

2013

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Evernimicin Binds Exclusively to the 50S Ribosomal Subunit and Inhibits Translation in Cell-Free Systems Derived from both Gram-Positive and Gram-Negative Bacteria

Antimicrobial Agents and Chemotherapy, 2000-05, Vol.44 (5), p.1121-1126

2000

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Global tectonic significance of the Solomon Islands and Ontong Java Plateau convergent zone

Tectonophysics, 2004-10, Vol.389 (3), p.137-190

2004

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Evolution of the Grenada and Tobago basins and implications for arc migration

Marine and petroleum geology, 2011, Vol.28 (1), p.235-258

2011

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Global catalogue, classification and tectonic origins of restraining- and releasing bends on active and ancient strike-slip fault systems

Geological Society special publication, 2007-01, Vol.290 (1), p.13-142

Mann, P.

2007

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Tectonics of strike-slip restraining and releasing bends

Geological Society special publication, 2007-01, Vol.290 (1), p.1-12

2007

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Effects of Mutations in Ribosomal Protein L16 on Susceptibility and Accumulation of Evernimicin

Antimicrobial Agents and Chemotherapy, 2001-01, Vol.45 (1), p.79-83

2001

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Regional structure and tectonic history of the obliquely colliding Columbus foreland basin, offshore Trinidad and Venezuela

Marine and petroleum geology, 2011, Vol.28 (1), p.126-148

2011

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Seismological structure and implications of collision between the Ontong Java Plateau and Solomon Island Arc from ocean bottom seismometer–airgun data

Tectonophysics, 2004-10, Vol.389 (3), p.191-220

2004

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Neogene–Quaternary tectonic evolution of the Leeward Antilles islands (Aruba, Bonaire, Curaçao) from fault kinematic analysis

Marine and petroleum geology, 2011, Vol.28 (1), p.259-277

2011

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Triangulation-to-GPS and GPS-to-GPS geodesy in Trinidad, West Indies: Neotectonics, seismic risk, and geologic implications

Marine and petroleum geology, 2011, Vol.28 (1), p.200-211

2011

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Role of the shale tectonics on the evolution of the Eastern Venezuelan Cenozoic thrust and fold belt

Marine and petroleum geology, 2011, Vol.28 (1), p.81-108

2011

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Chemical Genetic Analysis and Functional Characterization of Staphylococcal Wall Teichoic Acid 2-Epimerases Reveals Unconventional Antibiotic Drug Targets

Impact of Antifungal Prophylaxis on Colonization and Azole Susceptibility of Candida Species

Chemical Genomics-Based Antifungal Drug Discovery: Targeting Glycosylphosphatidylinositol (GPI) Precursor Biosynthesis

Multiple Resistance Mechanisms among Aspergillus fumigatus Mutants with High-Level Resistance to Itraconazole

Mutations in Aspergillus fumigatus Resulting in Reduced Susceptibility to Posaconazole Appear To Be Restricted to a Single Amino Acid in the Cytochrome P450 14α-Demethylase

Selective small-molecule inhibition of an RNA structural element

Mapping and characterization of vicriviroc resistance mutations from HIV-1 isolated from treatment-experienced subjects enrolled in a phase II study (VICTOR-E1)

Dual-Targeting Small-Molecule Inhibitors of the Staphylococcus aureus FMN Riboswitch Disrupt Riboflavin Homeostasis in an Infectious Setting

Posaconazole Is a Potent Inhibitor of Sterol 14α-Demethylation in Yeasts and Molds

Molecular Basis for Enhanced Activity of Posaconazole against Absidia corymbifera and Rhizopus oryzae

Tectonics, basin subsidence mechanisms, and paleogeography of the Caribbean-South American plate boundary zone

Inhibitor of intramembrane protease RseP blocks the σE response causing lethal accumulation of unfolded outer membrane proteins

Murgocil is a Highly Bioactive Staphylococcal-Specific Inhibitor of the Peptidoglycan Glycosyltransferase Enzyme MurG

Evernimicin Binds Exclusively to the 50S Ribosomal Subunit and Inhibits Translation in Cell-Free Systems Derived from both Gram-Positive and Gram-Negative Bacteria

Cerastecins inhibit membrane lipooligosaccharide transport in drug-resistant Acinetobacter baumannii

Global tectonic significance of the Solomon Islands and Ontong Java Plateau convergent zone

Evolution of the Grenada and Tobago basins and implications for arc migration

Global catalogue, classification and tectonic origins of restraining- and releasing bends on active and ancient strike-slip fault systems

Tectonics of strike-slip restraining and releasing bends

Effects of Mutations in Ribosomal Protein L16 on Susceptibility and Accumulation of Evernimicin

Regional structure and tectonic history of the obliquely colliding Columbus foreland basin, offshore Trinidad and Venezuela

Seismological structure and implications of collision between the Ontong Java Plateau and Solomon Island Arc from ocean bottom seismometer–airgun data

Neogene–Quaternary tectonic evolution of the Leeward Antilles islands (Aruba, Bonaire, Curaçao) from fault kinematic analysis

Triangulation-to-GPS and GPS-to-GPS geodesy in Trinidad, West Indies: Neotectonics, seismic risk, and geologic implications

Role of the shale tectonics on the evolution of the Eastern Venezuelan Cenozoic thrust and fold belt

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