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Histone deacetylase 3 inhibition improves glycaemia and insulin secretion in obese diabetic rats

Diabetes, obesity & metabolism, 2015-07, Vol.17 (7), p.703-707

2015

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Iron: the hard player in diabetes pathophysiology

Acta Physiologica, 2014-04, Vol.210 (4), p.717-732

2014

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Age-dependent decline of β-cell function in type 1 diabetes after diagnosis: a multi-centre longitudinal study

Diabetes, obesity & metabolism, 2014-03, Vol.16 (3), p.262-267

2014

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A choice of death -the signal-transduction of immune-mediated beta-cell apoptosis

Diabetologia, 2001-12, Vol.44 (12), p.2115-2133

2001

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global diabetes epidemic as a consequence of lifestyle-induced low-grade inflammation

Diabetologia, 2010, Vol.53 (1), p.10-20

2010

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Proliferation of sorted human and rat beta cells

Diabetologia, 2008-01, Vol.51 (1), p.91-100

2008

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An immune origin of type 2 diabetes?

Diabetologia, 2005-06, Vol.48 (6), p.1038-1050

2005

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The role of interleukin-1 in the pathogenesis of IDDM

Diabetologia, 1996-09, Vol.39 (9), p.1005-1029

MANDRUP-POULSEN, T

1996

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Inhibition of histone deacetylases prevents cytokine-induced toxicity in beta cells

Diabetologia, 2007-04, Vol.50 (4), p.779-789

2007

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Small-molecule inhibition of inflammatory β-cell death

Diabetes, obesity & metabolism, 2013-09, Vol.15 (s3), p.176-184

2013

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Nitric oxide contributes to cytokine-induced apoptosis in pancreatic beta cells via potentiation of JNK activity and inhibition of Akt

Diabetologia, 2005-10, Vol.48 (10), p.2039-2050

2005

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Cytokines and Pancreatic β-Cell Apoptosis

Advances in clinical chemistry, 2016, Vol.75, p.99-158

2016

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β-cell apoptosis : Stimuli and signaling

Diabetes (New York, N.Y.), 2001-02, Vol.50 (suppl_1), p.S58-S63

MANDRUP-POULSEN, Thomas

2001

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The c-Jun amino-terminal kinase pathway is preferentially activated by interleukin-1 and controls apoptosis in differentiating pancreatic beta-cells

Diabetes (New York, N.Y.), 2000-09, Vol.49 (9), p.1468-1476

2000

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Limited benefit of haemoglobin glycation index as risk factor for cardiovascular disease in type 2 diabetes patients

Diabetes & metabolism, 2019-06, Vol.45 (3), p.254-260

2019

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Functional SOCS1 polymorphisms are associated with variation in obesity in whites

Diabetes, obesity & metabolism, 2009-03, Vol.11 (3), p.196-203

2009

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Histone deacetylases 1 and 3 but not 2 mediate cytokine-induced beta cell apoptosis in INS-1 cells and dispersed primary islets from rats and are differentially regulated in the islets of type 1 diabetic children

Diabetologia, 2012-09, Vol.55 (9), p.2421-2431

2012

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BMI is an important driver of β-cell loss in type 1 diabetes upon diagnosis in 10 to 18-year-old children

European journal of endocrinology, 2015-02, Vol.172 (2), p.107-113

2015

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Lysine deacetylases are produced in pancreatic beta cells and are differentially regulated by proinflammatory cytokines

Diabetologia, 2010-12, Vol.53 (12), p.2569-2578

2010

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Association of immune mediators at diagnosis of Type 1 diabetes with later clinical remission

Diabetic medicine, 2007-05, Vol.24 (5), p.512-520

2007

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IL-1β induced protein changes in diabetes prone BB rat islets of Langerhans identified by proteome analysis

Diabetologia, 2002-11, Vol.45 (11), p.1550-1561

2002

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Association of interferon‐γ and interleukin 10 genotypes and serum levels with partial clinical remission in type 1 diabetes

Clinical and experimental immunology, 2006-09, Vol.145 (3), p.480-484

2006

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Variations of the interleukin-6 promoter are associated with features of the metabolic syndrome in Caucasian danes

Diabetologia, 2005-02, Vol.48 (2), p.251-260

2005

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Multifactorial treatment increases endothelial progenitor cells in patients with type 2 diabetes

Diabetologia, 2010-10, Vol.53 (10), p.2129-2133

2010

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Fasting and meal-stimulated residual beta cell function is positively associated with serum concentrations of proinflammatory cytokines and negatively associated with anti-inflammatory and regulatory cytokines in patients with longer term type 1 diabetes

Diabetologia, 2013-06, Vol.56 (6), p.1356-1363

2013

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Histone deacetylase 3 inhibition improves glycaemia and insulin secretion in obese diabetic rats

Iron: the hard player in diabetes pathophysiology

Age-dependent decline of β-cell function in type 1 diabetes after diagnosis: a multi-centre longitudinal study

A choice of death -the signal-transduction of immune-mediated beta-cell apoptosis

global diabetes epidemic as a consequence of lifestyle-induced low-grade inflammation

Proliferation of sorted human and rat beta cells

An immune origin of type 2 diabetes?

The role of interleukin-1 in the pathogenesis of IDDM

Inhibition of histone deacetylases prevents cytokine-induced toxicity in beta cells

Small-molecule inhibition of inflammatory β-cell death

Nitric oxide contributes to cytokine-induced apoptosis in pancreatic beta cells via potentiation of JNK activity and inhibition of Akt

Cytokines and Pancreatic β-Cell Apoptosis

β-cell apoptosis : Stimuli and signaling

The c-Jun amino-terminal kinase pathway is preferentially activated by interleukin-1 and controls apoptosis in differentiating pancreatic beta-cells

Limited benefit of haemoglobin glycation index as risk factor for cardiovascular disease in type 2 diabetes patients

Functional SOCS1 polymorphisms are associated with variation in obesity in whites

Histone deacetylases 1 and 3 but not 2 mediate cytokine-induced beta cell apoptosis in INS-1 cells and dispersed primary islets from rats and are differentially regulated in the islets of type 1 diabetic children

BMI is an important driver of β-cell loss in type 1 diabetes upon diagnosis in 10 to 18-year-old children

Lysine deacetylases are produced in pancreatic beta cells and are differentially regulated by proinflammatory cytokines

Association of immune mediators at diagnosis of Type 1 diabetes with later clinical remission

IL-1β induced protein changes in diabetes prone BB rat islets of Langerhans identified by proteome analysis

Association of interferon‐γ and interleukin 10 genotypes and serum levels with partial clinical remission in type 1 diabetes

Variations of the interleukin-6 promoter are associated with features of the metabolic syndrome in Caucasian danes

Multifactorial treatment increases endothelial progenitor cells in patients with type 2 diabetes

Fasting and meal-stimulated residual beta cell function is positively associated with serum concentrations of proinflammatory cytokines and negatively associated with anti-inflammatory and regulatory cytokines in patients with longer term type 1 diabetes

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