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A new antibiotic selectively kills Gram-negative pathogens

Nature (London), 2019-12, Vol.576 (7787), p.459-464

2019

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Crystal structures of agonist-bound human cannabinoid receptor CB1

Nature (London), 2017-07, Vol.547 (7664), p.468-471

2017

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Crystal Structure of the Human Cannabinoid Receptor CB2

Cell, 2019-01, Vol.176 (3), p.459-467.e13

2019

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Chronic Cannabinoid Receptor 2 Activation Reverses Paclitaxel Neuropathy Without Tolerance or Cannabinoid Receptor 1–Dependent Withdrawal

Biological psychiatry (1969), 2015-03, Vol.77 (5), p.475-487

2015

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Activation and Signaling Mechanism Revealed by Cannabinoid Receptor-Gi Complex Structures

Cell, 2020-02, Vol.180 (4), p.655-665.e18

2020

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Crystal Structure of the Human Cannabinoid Receptor CB1

Cell, 2016-10, Vol.167 (3), p.750-762.e14

2016

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Endocannabinoid Signaling Regulates Sleep Stability

PloS one, 2016-03, Vol.11 (3), p.e0152473

2016

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Peripheral CB1 cannabinoid receptor blockade improves cardiometabolic risk in mouse models of obesity

The Journal of clinical investigation, 2010-08, Vol.120 (8), p.2953-2966

2010

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Inhibition of triple negative breast cancer-associated inflammation, tumor growth and brain colonization by targeting monoacylglycerol lipase

Scientific reports, 2022-03, Vol.12 (1), p.5328-5328, Article 5328

2022

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peripheral endocannabinoid mechanism contributes to glucocorticoid-mediated metabolic syndrome

Proceedings of the National Academy of Sciences - PNAS, 2015-01, Vol.112 (1), p.285-290

2015

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Adipocyte cannabinoid receptor CB1 regulates energy homeostasis and alternatively activated macrophages

The Journal of clinical investigation, 2017-11, Vol.127 (11), p.4148-4162

2017

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Structural basis for activation of CB1 by an endocannabinoid analog

Nature communications, 2023-05, Vol.14 (1), p.2672-2672, Article 2672

2023

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N-acylethanolamine-hydrolyzing acid amidase and fatty acid amide hydrolase inhibition differentially affect N-acylethanolamine levels and macrophage activation

Biochimica et biophysica acta. Molecular and cell biology of lipids, 2017-05, Vol.1862 (5), p.474-484

2017

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Biochemical and Proteomic Characterization of Recombinant Human α/β Hydrolase Domain 6

Scientific reports, 2019-01, Vol.9 (1), p.890-890, Article 890

2019

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Investigating the Effects of Exogenous and Endogenous 2-Arachidonoylglycerol on Retinal CB1 Cannabinoid Receptors and Reactive Microglia in Naive and Diseased Retina

International journal of molecular sciences, 2023-11, Vol.24 (21), p.15689

2023

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Cannabinoid receptor antagonists: pharmacological opportunities, clinical experience, and translational prognosis

Expert opinion on emerging drugs, 2009-03, Vol.14 (1), p.43-65

2009

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Cannabinoid CB1 Receptors Inhibit Gut-Brain Satiation Signaling in Diet-Induced Obesity

Frontiers in physiology, 2019-06, Vol.10, p.704-704

2019

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N-Acylethanolamine Acid Amidase Inhibition Potentiates Morphine Analgesia and Delays the Development of Tolerance

Neurotherapeutics, 2021-10, Vol.18 (4), p.2722-2736

2021

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Blockade of CB1 or Activation of CB2 Cannabinoid Receptors Is Differentially Efficacious in the Treatment of the Early Pathological Events in Streptozotocin-Induced Diabetic Rats

International journal of molecular sciences, 2022-12, Vol.24 (1), p.240

2022

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Correction: Eid et al. Interference with TGFβ1-Mediated Inflammation and Fibrosis Underlies Reno-Protective Effects of the CB1 Receptor Neutral Antagonists AM6545 and AM4113 in a Rat Model of Metabolic Syndrome. Molecules 2021, 26 , 866

Molecules (Basel, Switzerland), 2024-02, Vol.29 (4), p.902

2024

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Complex 33-beam simulated galactic cosmic radiation exposure impacts cognitive function and prefrontal cortex neurotransmitter networks in male mice

Nature communications, 2023-11, Vol.14 (1), p.7779-7779, Article 7779

2023

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Cannabinoid CB2 receptors in primary sensory neurons are implicated in CB2 agonist-mediated suppression of paclitaxel-induced neuropathic nociception and sexually-dimorphic sparing of morphine tolerance

Biomedicine & pharmacotherapy, 2024-07, Vol.176, p.116879-116879, Article 116879

2024

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2012 Division of Medicinal Chemistry Award Address. Trekking the Cannabinoid Road: A Personal Perspective

Journal of medicinal chemistry, 2014-05, Vol.57 (10), p.3891-3911

Makriyannis, Alexandros

2014

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Inhibition of triple negative breast cancer-associated inflammation and progression by N- acylethanolamine acid amide hydrolase (NAAA)

Scientific reports, 2022-12, Vol.12 (1), p.22255-22255, Article 22255

2022

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Design and synthesis of cyanamides as potent and selective N-acylethanolamine acid amidase inhibitors

Bioorganic & medicinal chemistry, 2020-01, Vol.28 (1), p.115195, Article 115195

2020

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A new antibiotic selectively kills Gram-negative pathogens

Crystal structures of agonist-bound human cannabinoid receptor CB1

Crystal Structure of the Human Cannabinoid Receptor CB2

Chronic Cannabinoid Receptor 2 Activation Reverses Paclitaxel Neuropathy Without Tolerance or Cannabinoid Receptor 1–Dependent Withdrawal

Activation and Signaling Mechanism Revealed by Cannabinoid Receptor-Gi Complex Structures

Crystal Structure of the Human Cannabinoid Receptor CB1

Endocannabinoid Signaling Regulates Sleep Stability

Peripheral CB1 cannabinoid receptor blockade improves cardiometabolic risk in mouse models of obesity

Inhibition of triple negative breast cancer-associated inflammation, tumor growth and brain colonization by targeting monoacylglycerol lipase

peripheral endocannabinoid mechanism contributes to glucocorticoid-mediated metabolic syndrome

Adipocyte cannabinoid receptor CB1 regulates energy homeostasis and alternatively activated macrophages

Structural basis for activation of CB1 by an endocannabinoid analog

N-acylethanolamine-hydrolyzing acid amidase and fatty acid amide hydrolase inhibition differentially affect N-acylethanolamine levels and macrophage activation

Biochemical and Proteomic Characterization of Recombinant Human α/β Hydrolase Domain 6

Investigating the Effects of Exogenous and Endogenous 2-Arachidonoylglycerol on Retinal CB1 Cannabinoid Receptors and Reactive Microglia in Naive and Diseased Retina

Cannabinoid receptor antagonists: pharmacological opportunities, clinical experience, and translational prognosis

Cannabinoid CB1 Receptors Inhibit Gut-Brain Satiation Signaling in Diet-Induced Obesity

N-Acylethanolamine Acid Amidase Inhibition Potentiates Morphine Analgesia and Delays the Development of Tolerance

Blockade of CB1 or Activation of CB2 Cannabinoid Receptors Is Differentially Efficacious in the Treatment of the Early Pathological Events in Streptozotocin-Induced Diabetic Rats

Correction: Eid et al. Interference with TGFβ1-Mediated Inflammation and Fibrosis Underlies Reno-Protective Effects of the CB1 Receptor Neutral Antagonists AM6545 and AM4113 in a Rat Model of Metabolic Syndrome. Molecules 2021, 26 , 866

Complex 33-beam simulated galactic cosmic radiation exposure impacts cognitive function and prefrontal cortex neurotransmitter networks in male mice

Cannabinoid CB2 receptors in primary sensory neurons are implicated in CB2 agonist-mediated suppression of paclitaxel-induced neuropathic nociception and sexually-dimorphic sparing of morphine tolerance

2012 Division of Medicinal Chemistry Award Address. Trekking the Cannabinoid Road: A Personal Perspective

Inhibition of triple negative breast cancer-associated inflammation and progression by N- acylethanolamine acid amide hydrolase (NAAA)

Design and synthesis of cyanamides as potent and selective N-acylethanolamine acid amidase inhibitors

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