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Mipsagargin, a novel thapsigargin-based PSMA-activated prodrug: results of a first-in-man phase I clinical trial in patients with refractory, advanced or metastatic solid tumours

British journal of cancer, 2016-04, Vol.114 (9), p.986-994

2016

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Targeting HSP90 for cancer therapy

British journal of cancer, 2009-05, Vol.100 (10), p.1523-1529

2009

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Reovirus therapy stimulates endoplasmic reticular stress, NOXA induction, and augments bortezomib-mediated apoptosis in multiple myeloma

Oncogene, 2012-06, Vol.31 (25), p.3023-3038

2012

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Effects of supplementation with tocotrienol-rich fraction on immune response to tetanus toxoid immunization in normal healthy volunteers

European journal of clinical nutrition, 2011-01, Vol.65 (1), p.63-69

2011

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Mipsagargin, a PSMA-directed prodrug, provides clinical benefit in patients with advanced sorafenib-refractory hepatocellular carcinoma

Journal of hepatology, 2017, Vol.66 (1), p.S207-S207

2017

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Early growth response-1 is a regulator of DR5-induced apoptosis in colon cancer cells

British journal of cancer, 2010-02, Vol.102 (4), p.754-764

2010

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Novel small-molecule RORγ agonist immuno-oncology agent LYC-55716: Safety and efficacy in a phase IIA open-label, multicenter trial

Annals of oncology, 2018-10, Vol.29, p.viii404-viii405

2018

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PD-016Current results of a phase I study of DKN-01 in combination with paclitaxel (P) in patients (pts) with advanced DKK1+ esophageal cancer (EC) or gastro-esophageal junction tumors (GEJ)

Annals of oncology, 2016-06, Vol.27 (suppl_2), p.ii108-ii108

2016

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Differential activation of JNK1 isoforms by TRAIL receptors modulate apoptosis of colon cancer cell lines

British journal of cancer, 2009-05, Vol.100 (9), p.1415-1424

2009

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Mitogen-activated protein kinase phosphatase 1 regulates bone mass, osteoblast gene expression, and responsiveness to parathyroid hormone

Journal of endocrinology, 2011-11, Vol.211 (2), p.145-156

2011

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Cell Cycle and Apoptosis Regulatory Protein (CARP)-1 is Expressed inOsteoblasts and Regulated by PTH

Biochemical and biophysical research communications, 2013-07, Vol.436 (4), p.607-612

2013

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Tissue‐engineered tendon constructs for rotator cuff repair in sheep

Journal of orthopaedic research, 2018-01, Vol.36 (1), p.289-299

2018

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PD-011Safety and efficacy analysis of imalumab, an anti-oxidized macrophage migration inhibitory factor (oxMIF) antibody, alone or in combination with 5-fluorouracil/leucovorin (5-FU/LV) or panitumumab, in patients with metastatic colorectal cancer (mCRC)

Annals of oncology, 2016-06, Vol.27 (suppl_2), p.ii105-ii105

2016

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Targeting PIM kinase enhances the activity of sunitinib in renal cell carcinoma

British journal of cancer, 2011-11, Vol.105 (10), p.1563-1573

2011

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Role of PTH1R internalization in osteoblasts and bone mass using a phosphorylation-deficient knock-in mouse model

Journal of endocrinology, 2010-12, Vol.207 (3), p.355-365

2010

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Clear cell renal cell carcinoma cells show diffuse expression of phagocytotic markers through the identification of lysosome-rich eosinophilic granules

International urology and nephrology, 2024-02, Vol.56 (2), p.467-473

2024

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Punctate IgG staining particles localize in the budding ballooning clusters of reactive foot processes in minimal change disease

Ultrastructural pathology, 2024-03, Vol.48 (2), p.121-127

2024

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601 A First-in-human, Phase 1 Clinical Study of the Safety, Tolerability and Pharmacokinetics (PK) of G-202, a Thapsigargin-based PSMA-activated Prodrug, in Patients with Advanced Solid Tumors

European journal of cancer (1990), 2012-11, Vol.48, p.184-185

2012

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555 A Study of REOLYSIN in Combination with Gemcitabine in Patients with Advanced Pancreatic Adenocarcinoma

European journal of cancer (1990), 2012-11, Vol.48, p.170-171

2012

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87 Inhibition of Autophagy: a Phase 1 Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Analysis of Hydroxychloroquine in Combination with the HDAC Inhibitor, Vorinostat, in Patients with Advanced Solid Tumors

European journal of cancer (1990), 2012-11, Vol.48, p.28-28

2012

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Green Synthesized Metal Nanoparticles, Characterization and its Antidiabetic activities-A Review

Research journal of pharmacy and technology, 2020-01, Vol.13 (1), p.468-474

2020

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A first-in-human, open-label, multicenter phase 1/2a study to evaluate the safety and efficacy of increased repeated doses of the first in class RORγ agonist LYC-55716 in treating locally advanced or metastatic solid tumors

Annals of oncology, 2017-09, Vol.28, p.v426-v426

2017

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A first-in-human, open-label, multicenter phase 1/2a study to evaluate the safety and efficacy of increased repeated doses of the first in class RORγ agonist LYC-55716 in treating locally advanced or metastatic solid tumors

Annals of oncology, 2017-09, Vol.28, p.v426-v426

2017

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A Case Report of Autopsy: Large Mass of Pulmonary Metastatic Calcification in a Patient with End-Stage Renal Disease

American journal of clinical pathology, 2021-10, Vol.156 (Supplement_1), p.S24-S24

2021

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Persistent prevention of oxaliplatin-induced peripheral neuropathy using calmangafodipir (PledOx ® ): a placebo-controlled randomised phase II study (PLIANT)

Acta oncologica, 2018-01, Vol.57 (3), p.393-402

2018

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Mipsagargin, a novel thapsigargin-based PSMA-activated prodrug: results of a first-in-man phase I clinical trial in patients with refractory, advanced or metastatic solid tumours

Targeting HSP90 for cancer therapy

Reovirus therapy stimulates endoplasmic reticular stress, NOXA induction, and augments bortezomib-mediated apoptosis in multiple myeloma

Effects of supplementation with tocotrienol-rich fraction on immune response to tetanus toxoid immunization in normal healthy volunteers

Mipsagargin, a PSMA-directed prodrug, provides clinical benefit in patients with advanced sorafenib-refractory hepatocellular carcinoma

Early growth response-1 is a regulator of DR5-induced apoptosis in colon cancer cells

Novel small-molecule RORγ agonist immuno-oncology agent LYC-55716: Safety and efficacy in a phase IIA open-label, multicenter trial

PD-016Current results of a phase I study of DKN-01 in combination with paclitaxel (P) in patients (pts) with advanced DKK1+ esophageal cancer (EC) or gastro-esophageal junction tumors (GEJ)

Differential activation of JNK1 isoforms by TRAIL receptors modulate apoptosis of colon cancer cell lines

Mitogen-activated protein kinase phosphatase 1 regulates bone mass, osteoblast gene expression, and responsiveness to parathyroid hormone

Cell Cycle and Apoptosis Regulatory Protein (CARP)-1 is Expressed inOsteoblasts and Regulated by PTH

Tissue‐engineered tendon constructs for rotator cuff repair in sheep

PD-011Safety and efficacy analysis of imalumab, an anti-oxidized macrophage migration inhibitory factor (oxMIF) antibody, alone or in combination with 5-fluorouracil/leucovorin (5-FU/LV) or panitumumab, in patients with metastatic colorectal cancer (mCRC)

Targeting PIM kinase enhances the activity of sunitinib in renal cell carcinoma

Role of PTH1R internalization in osteoblasts and bone mass using a phosphorylation-deficient knock-in mouse model

Clear cell renal cell carcinoma cells show diffuse expression of phagocytotic markers through the identification of lysosome-rich eosinophilic granules

Punctate IgG staining particles localize in the budding ballooning clusters of reactive foot processes in minimal change disease

601 A First-in-human, Phase 1 Clinical Study of the Safety, Tolerability and Pharmacokinetics (PK) of G-202, a Thapsigargin-based PSMA-activated Prodrug, in Patients with Advanced Solid Tumors

555 A Study of REOLYSIN in Combination with Gemcitabine in Patients with Advanced Pancreatic Adenocarcinoma

87 Inhibition of Autophagy: a Phase 1 Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Analysis of Hydroxychloroquine in Combination with the HDAC Inhibitor, Vorinostat, in Patients with Advanced Solid Tumors

Green Synthesized Metal Nanoparticles, Characterization and its Antidiabetic activities-A Review

A first-in-human, open-label, multicenter phase 1/2a study to evaluate the safety and efficacy of increased repeated doses of the first in class RORγ agonist LYC-55716 in treating locally advanced or metastatic solid tumors

A first-in-human, open-label, multicenter phase 1/2a study to evaluate the safety and efficacy of increased repeated doses of the first in class RORγ agonist LYC-55716 in treating locally advanced or metastatic solid tumors

A Case Report of Autopsy: Large Mass of Pulmonary Metastatic Calcification in a Patient with End-Stage Renal Disease

Persistent prevention of oxaliplatin-induced peripheral neuropathy using calmangafodipir (PledOx ® ): a placebo-controlled randomised phase II study (PLIANT)

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