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SARS‐CoV‐2 targets neurons of 3D human brain organoids

The EMBO journal, 2020-10, Vol.39 (20), p.e106230-n/a

2020

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Soluble amyloid‐β dimers are resistant to amyloid‐β prion conversion in vivo suggesting antiprion properties

Neuropathology and applied neurobiology, 2023-04, Vol.49 (2), p.e12895-n/a

2023

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The interaction of insoluble Amyloid‐β with soluble Amyloid‐β dimers decreases Amyloid‐β plaque numbers

Neuropathology and applied neurobiology, 2021-08, Vol.47 (5), p.603-610

2021

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Biophysical insights from a single chain camelid antibody directed against the Disrupted-in-Schizophrenia 1 protein

PloS one, 2018-01, Vol.13 (1), p.e0191162-e0191162

2018

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Viruses as ‘Truffle Hounds’: Molecular Tools for Untangling Brain Cellular Pathology

Trends in neurosciences (Regular ed.), 2021-05, Vol.44 (5), p.352-365

2021

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Characterizing the Effect of Multivalent Conjugates Composed of Aβ-Specific Ligands and Metal Nanoparticles on Neurotoxic Fibrillar Aggregation

ACS nano, 2016-08, Vol.10 (8), p.7582-7597

2016

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The E6 Protein of the Cutaneous Human Papillomavirus Type 8 Can Stimulate the Viral Early and Late Promoters by Distinct Mechanisms

Journal of Virology, 2006-09, Vol.80 (17), p.8718-8728

2006

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Hybrid Compounds: From Simple Combinations to Nanomachines

BioDrugs : clinical immunotherapeutics, biopharmaceuticals, and gene therapy, 2012-02, Vol.26 (1), p.21-31

2012

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IPSC-Derived Neuronal Cultures Carrying the Alzheimer's Disease Associated TREM2 R47H Variant Enables the Construction of an Aβ-Induced Gene Regulatory Network

International journal of molecular sciences, 2020-06, Vol.21 (12), p.4516

2020

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BRI2-BRICHOS is increased in human amyloid plaques in early stages of Alzheimer's disease

Neurobiology of aging, 2014-07, Vol.35 (7), p.1596-1604

2014

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Oral Treatment with the d-Enantiomeric Peptide D3 Improves the Pathology and Behavior of Alzheimer’s Disease Transgenic Mice

ACS chemical neuroscience, 2010-09, Vol.1 (9), p.639-648

2010

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Combining Independent Drug Classes into Superior, Synergistically Acting Hybrid Molecules

Angewandte Chemie (International ed.), 2010-11, Vol.49 (46), p.8743-8746

2010

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Hybrid molecules synergistically acting against protein aggregation diseases

Current topics in medicinal chemistry, 2013-10, Vol.13 (19), p.2484

2013

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Gesteigerte Wirksamkeit durch Synergismus: Verknüpfung unabhängiger Wirkstoffklassen zu Hybridsubstanzen

Angewandte Chemie, 2010-11, Vol.122 (46), p.8925-8928

2010

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Biological Effects and Use of PrPSc- and PrP-Specific Antibodies Generated by Immunization with Purified Full-Length Native Mouse Prions

Journal of Virology, 2011-05, Vol.85 (9), p.4538-4546

2011

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Characterization of a single-chain variable fragment recognizing a linear epitope of aβ: a biotechnical tool for studies on Alzheimer's disease?

PloS one, 2013-03, Vol.8 (3), p.e59820-e59820

2013

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Protein tyrosine phosphatase H1 is a target of the E6 oncoprotein of high-risk genital human papillomaviruses

Journal of general virology, 2007-11, Vol.88 (11), p.2956-2965

2007

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Vaccine Approaches to Prevent and Treat Prion Infection: Progress and Challenges

BioDrugs : clinical immunotherapeutics, biopharmaceuticals, and gene therapy, 2008, Vol.22 (1), p.45-52

2008

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Molecular Engineering of a Secreted, Highly Homogeneous, and Neurotoxic Aβ Dimer

ACS chemical neuroscience, 2011-05, Vol.2 (5), p.242-248

2011

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Complementarity determining regions of an anti-prion protein scFv fragment orchestrate conformation specificity and antiprion activity

Molecular immunology, 2009-02, Vol.46 (4), p.532-540

2009

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Amyloid-β dimers in the absence of plaque pathology impair learning and synaptic plasticity

Brain (London, England : 1878), 2016-02, Vol.139 (Pt 2), p.509-525

2016

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E2 and the co-activator p300 can cooperate in activation of the human papillomavirus type 16 early promoter

Virology (New York, N.Y.), 2008-07, Vol.377 (1), p.151-159

2008

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C-terminal fragment of N-cadherin accelerates synapse destabilization by amyloid-β

Brain (London, England : 1878), 2012-07, Vol.135 (Pt 7), p.2140-2154

2012

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All - d - Enantiomeric Peptide D3 Designed for Alzheimer's Disease Treatment Dynamically Interacts with Membrane-Bound Amyloid-β Precursors

Journal of medicinal chemistry, 2021-11, Vol.64 (22), p.16464-16479

2021

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SARS‐CoV‐2 targets neurons of 3D human brain organoids

Soluble amyloid‐β dimers are resistant to amyloid‐β prion conversion in vivo suggesting antiprion properties

The interaction of insoluble Amyloid‐β with soluble Amyloid‐β dimers decreases Amyloid‐β plaque numbers

Biophysical insights from a single chain camelid antibody directed against the Disrupted-in-Schizophrenia 1 protein

Viruses as ‘Truffle Hounds’: Molecular Tools for Untangling Brain Cellular Pathology

Characterizing the Effect of Multivalent Conjugates Composed of Aβ-Specific Ligands and Metal Nanoparticles on Neurotoxic Fibrillar Aggregation

The E6 Protein of the Cutaneous Human Papillomavirus Type 8 Can Stimulate the Viral Early and Late Promoters by Distinct Mechanisms

Hybrid Compounds: From Simple Combinations to Nanomachines

IPSC-Derived Neuronal Cultures Carrying the Alzheimer's Disease Associated TREM2 R47H Variant Enables the Construction of an Aβ-Induced Gene Regulatory Network

BRI2-BRICHOS is increased in human amyloid plaques in early stages of Alzheimer's disease

Oral Treatment with the d-Enantiomeric Peptide D3 Improves the Pathology and Behavior of Alzheimer’s Disease Transgenic Mice

Combining Independent Drug Classes into Superior, Synergistically Acting Hybrid Molecules

Hybrid molecules synergistically acting against protein aggregation diseases

Gesteigerte Wirksamkeit durch Synergismus: Verknüpfung unabhängiger Wirkstoffklassen zu Hybridsubstanzen

Biological Effects and Use of PrPSc- and PrP-Specific Antibodies Generated by Immunization with Purified Full-Length Native Mouse Prions

Characterization of a single-chain variable fragment recognizing a linear epitope of aβ: a biotechnical tool for studies on Alzheimer's disease?

Protein tyrosine phosphatase H1 is a target of the E6 oncoprotein of high-risk genital human papillomaviruses

Vaccine Approaches to Prevent and Treat Prion Infection: Progress and Challenges

Molecular Engineering of a Secreted, Highly Homogeneous, and Neurotoxic Aβ Dimer

Complementarity determining regions of an anti-prion protein scFv fragment orchestrate conformation specificity and antiprion activity

Amyloid-β dimers in the absence of plaque pathology impair learning and synaptic plasticity

E2 and the co-activator p300 can cooperate in activation of the human papillomavirus type 16 early promoter

C-terminal fragment of N-cadherin accelerates synapse destabilization by amyloid-β

All - d - Enantiomeric Peptide D3 Designed for Alzheimer's Disease Treatment Dynamically Interacts with Membrane-Bound Amyloid-β Precursors

The Priority position paper: Protecting Europe's food chain from prions

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