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Mixed‐polarization phenotype of ascites‐associated macrophages in human ovarian carcinoma: Correlation of CD163 expression, cytokine levels and early relapse

International journal of cancer, 2014-01, Vol.134 (1), p.32-42

2014

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Arachidonic acid, a clinically adverse mediator in the ovarian cancer microenvironment, impairs JAK‐STAT signaling in macrophages by perturbing lipid raft structures

Molecular oncology, 2022-09, Vol.16 (17), p.3146-3166

2022

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Cell type‐selective pathways and clinical associations of lysophosphatidic acid biosynthesis and signaling in the ovarian cancer microenvironment

Molecular oncology, 2019-02, Vol.13 (2), p.185-201

2019

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Upregulation of mesothelial genes in ovarian carcinoma cells is associated with an unfavorable clinical outcome and the promotion of cancer cell adhesion

Molecular oncology, 2020-09, Vol.14 (9), p.2142-2162

2020

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The multicellular signalling network of ovarian cancer metastases

Clinical and translational medicine, 2021-11, Vol.11 (11), p.e633-n/a

2021

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Basal cell adhesion molecule promotes metastasis‐associated processes in ovarian cancer

Clinical and translational medicine, 2023-01, Vol.13 (1), p.e1176-n/a

2023

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Genomewide analyses define different modes of transcriptional regulation by peroxisome proliferator-activated receptor-β/δ (PPARβ/δ)

PloS one, 2011-01, Vol.6 (1), p.e16344-e16344

2011

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(Z)-2-(2-Bromophenyl)-3-{[4-(1-methyl-piperazine)amino]phenyl}acrylonitrile (DG172): An Orally Bioavailable PPARβ/δ-Selective Ligand with Inverse Agonistic Properties

Journal of medicinal chemistry, 2012-03, Vol.55 (6), p.2858-2868

2012

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TRAIL-dependent apoptosis of peritoneal mesothelial cells by NK cells promotes ovarian cancer invasion

iScience, 2023-12, Vol.26 (12), p.108401-108401, Article 108401

2023

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Chromatin Binding of c -REL and p65 Is Not Limiting for Macrophage IL12B Transcription During Immediate Suppression by Ovarian Carcinoma Ascites

Frontiers in immunology, 2018-06, Vol.9, p.1425-1425

2018

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Deregulation of tumor angiogenesis and blockade of tumor growth in PPARβ-deficient mice

The EMBO journal, 2007-08, Vol.26 (15), p.3686-3698

2007

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High-affinity peroxisome proliferator-activated receptor β/δ-specific ligands with pure antagonistic or inverse agonistic properties

Molecular pharmacology, 2011-11, Vol.80 (5), p.828-838

2011

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Design and Synthesis of Highly Active Peroxisome Proliferator-Activated Receptor (PPAR) β/δ Inverse Agonists with Prolonged Cellular Activity

ChemMedChem, 2016-03, Vol.11 (5), p.488-496

2016

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Cover Picture: Design and Synthesis of Highly Active Peroxisome Proliferator-Activated Receptor (PPAR) β/δ Inverse Agonists with Prolonged Cellular Activity (ChemMedChem 5/2016)

ChemMedChem, 2016-03, Vol.11 (5), p.445-445

2016

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Regulation of TAK1/TAB1-mediated IL-1β signaling by cytoplasmic PPARβ/δ

PloS one, 2013-04, Vol.8 (4), p.e63011

2013

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Expression level and agonist-binding affect the turnover, ubiquitination and complex formation of peroxisome proliferator activated receptor β

The FEBS journal, 2007-10, Vol.274 (19), p.5068-5076

2007

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Regulation of Cell Proliferation and Differentiation by PPARβ/δ

PPAR Research, 2008-01, Vol.2008 (2008), p.841-845-080

2008

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Induction of PPARβ and prostacyclin (PGI2) synthesis by Raf signaling: failure of PGI2 to activate PPARβ

The FEBS journal, 2006-01, Vol.273 (1), p.170-179

2006

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Proteomic profile of mouse fibroblasts with a targeted disruption of the peroxisome proliferator activated receptor-β/δ gene

Proteomics (Weinheim), 2007-04, Vol.7 (8), p.1208-1216

2007

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Growth of transgenic RAF-induced lung adenomas is increased in mice with a disrupted PPARβ/δ gene

International journal of oncology, 2007-09, Vol.31 (3), p.607-611

2007

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A Role for PPARβ/δ in Tumor Stroma and Tumorigenesis

PPAR Research, 2008-01, Vol.2008 (2008), p.771-775-071

2008

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Interferon signaling in ascites-associated macrophages is linked to a favorable clinical outcome in a subgroup of ovarian carcinoma patients

BMC genomics, 2017-03, Vol.18 (1), p.243-243, Article 243

2017

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A multi-stage process including transient polyploidization and EMT precedes the emergence of chemoresistent ovarian carcinoma cells with a dedifferentiated and pro-inflammatory secretory phenotype

Oncotarget, 2015-11, Vol.6 (37), p.40005-40025

2015

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The transcriptional signature of human ovarian carcinoma macrophages is associated with extracellular matrix reorganization

Oncotarget, 2016-11, Vol.7 (46), p.75339-75352

2016

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The transcriptional PPARβ/δ network in human macrophages defines a unique agonist-induced activation state

Nucleic acids research, 2015-05, Vol.43 (10), p.5033-5051

2015

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Mixed‐polarization phenotype of ascites‐associated macrophages in human ovarian carcinoma: Correlation of CD163 expression, cytokine levels and early relapse

Arachidonic acid, a clinically adverse mediator in the ovarian cancer microenvironment, impairs JAK‐STAT signaling in macrophages by perturbing lipid raft structures

Cell type‐selective pathways and clinical associations of lysophosphatidic acid biosynthesis and signaling in the ovarian cancer microenvironment

Upregulation of mesothelial genes in ovarian carcinoma cells is associated with an unfavorable clinical outcome and the promotion of cancer cell adhesion

The multicellular signalling network of ovarian cancer metastases

Basal cell adhesion molecule promotes metastasis‐associated processes in ovarian cancer

Genomewide analyses define different modes of transcriptional regulation by peroxisome proliferator-activated receptor-β/δ (PPARβ/δ)

(Z)-2-(2-Bromophenyl)-3-{[4-(1-methyl-piperazine)amino]phenyl}acrylonitrile (DG172): An Orally Bioavailable PPARβ/δ-Selective Ligand with Inverse Agonistic Properties

TRAIL-dependent apoptosis of peritoneal mesothelial cells by NK cells promotes ovarian cancer invasion

Chromatin Binding of c -REL and p65 Is Not Limiting for Macrophage IL12B Transcription During Immediate Suppression by Ovarian Carcinoma Ascites

Deregulation of tumor angiogenesis and blockade of tumor growth in PPARβ-deficient mice

High-affinity peroxisome proliferator-activated receptor β/δ-specific ligands with pure antagonistic or inverse agonistic properties

Design and Synthesis of Highly Active Peroxisome Proliferator-Activated Receptor (PPAR) β/δ Inverse Agonists with Prolonged Cellular Activity

Cover Picture: Design and Synthesis of Highly Active Peroxisome Proliferator-Activated Receptor (PPAR) β/δ Inverse Agonists with Prolonged Cellular Activity (ChemMedChem 5/2016)

Regulation of TAK1/TAB1-mediated IL-1β signaling by cytoplasmic PPARβ/δ

Expression level and agonist-binding affect the turnover, ubiquitination and complex formation of peroxisome proliferator activated receptor β

Regulation of Cell Proliferation and Differentiation by PPARβ/δ

Induction of PPARβ and prostacyclin (PGI2) synthesis by Raf signaling: failure of PGI2 to activate PPARβ

Proteomic profile of mouse fibroblasts with a targeted disruption of the peroxisome proliferator activated receptor-β/δ gene

Growth of transgenic RAF-induced lung adenomas is increased in mice with a disrupted PPARβ/δ gene

A Role for PPARβ/δ in Tumor Stroma and Tumorigenesis

Interferon signaling in ascites-associated macrophages is linked to a favorable clinical outcome in a subgroup of ovarian carcinoma patients

A multi-stage process including transient polyploidization and EMT precedes the emergence of chemoresistent ovarian carcinoma cells with a dedifferentiated and pro-inflammatory secretory phenotype

The transcriptional signature of human ovarian carcinoma macrophages is associated with extracellular matrix reorganization

The transcriptional PPARβ/δ network in human macrophages defines a unique agonist-induced activation state

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