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Functional architectures of animal toxins: a clue to drug design?

Toxicon (Oxford), 1998-11, Vol.36 (11), p.1557-1572

1998

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Isolation of a Tarantula Toxin Specific for a Class of Proton-gated Na+ Channels

The Journal of biological chemistry, 2000-08, Vol.275 (33), p.25116-25121

2000

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Bee Venom Phospholipase A2, a Good "Chauffeur" for Delivering Tumor Antigen to the MHC I and MHC II Peptide-Loading Compartments of the Dendritic Cells: The Case of NY-ESO-1

PloS one, 2013-06, Vol.8 (6), p.e67645-e67645

2013

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‘Venomics’ or: The venomous systems genome project

Toxicon (Oxford), 2006-03, Vol.47 (3), p.255-259

2006

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Structural Evidence for a Functional Role of Human Tissue Nonspecific Alkaline Phosphatase in Bone Mineralization

The Journal of biological chemistry, 2001-08, Vol.276 (33), p.31171-31178

2001

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Structural basis for the NAD‐hydrolysis mechanism and the ARTT‐loop plasticity of C3 exoenzymes

Protein science, 2008-05, Vol.17 (5), p.878-886

2008

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HLA-DR Restricted Peptide Candidates for Bee Venom Immunotherapy

The Journal of immunology (1950), 2000-03, Vol.164 (6), p.3177-3184

2000

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Experimentally Based Model of a Complex between a Snake Toxin and the α7 Nicotinic Receptor

Proceedings of the National Academy of Sciences - PNAS, 2002-03, Vol.99 (5), p.3216-3221

2002

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Rational Engineering of a Miniprotein That Reproduces the Core of the CD4 Site Interacting with HIV-1 Envelope Glycoprotein

Proceedings of the National Academy of Sciences - PNAS, 1999-11, Vol.96 (23), p.13091-13096

1999

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Fine Tuning of the Specificity of an Anti-progesterone Antibody by First and Second Sphere Residue Engineering

The Journal of biological chemistry, 2005-07, Vol.280 (26), p.24880-24887

2005

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A Variable Residue in the Pore of Kv1 Channels Is Critical for the High Affinity of Blockers from Sea Anemones and Scorpions

The Journal of biological chemistry, 2005-07, Vol.280 (29), p.27093-27102

2005

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Scanning the HIV Genome for CD4+ T Cell Epitopes Restricted to HLA-DP4, the Most Prevalent HLA Class II Molecule

The Journal of immunology (1950), 2006-05, Vol.176 (9), p.5401-5408

2006

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Refined Structure of Charybdotoxin: Common Motifs in Scorpion Toxins and Insect Defensins

Science (American Association for the Advancement of Science), 1991-12, Vol.254 (5037), p.1521-1523

1991

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Improving Escherichia coli Alkaline Phosphatase Efficacy by Additional Mutations inside and outside the Catalytic Pocket

Chembiochem : a European journal of chemical biology, 2001-08, Vol.2 (7-8), p.517-523

2001

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NAD Binding Induces Conformational Changes in Rho ADP-ribosylating Clostridium botulinum C3 Exoenzyme

The Journal of biological chemistry, 2002-08, Vol.277 (34), p.30950-30957

2002

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How Do Short Neurotoxins Bind to a Muscular-type Nicotinic Acetylcholine Receptor?

The Journal of biological chemistry, 2002-07, Vol.277 (28), p.25741-25747

2002

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Practical synthesis of Boc and Fmoc protected 4-fluoro and 4-difluoroprolines from trans-4-hydroxyproline

Tetrahedron letters, 1998-03, Vol.39 (10), p.1169-1172

1998

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Dual Expression System Suitable for High-Throughput Fluorescence-Based Screening and Production of Soluble Proteins

Journal of proteome research, 2005-11, Vol.4 (6), p.2137-2147

2005

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Structural features common to intracellularly acting toxins from bacteria

Toxicon (Oxford), 2005-02, Vol.45 (2), p.129-137

2005

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Molecular characterization of the specificity of interactions of various neurotoxins on two distinct nicotinic acetylcholine receptors

European journal of pharmacology, 2000-03, Vol.393 (1), p.197-204

2000

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Chemical engineering of a three-fingered toxin with anti-α7 neuronal acetylcholine receptor activity

Protein engineering, 2000-03, Vol.13 (3), p.217-225

2000

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Synthesis of optically pure N-Boc-protected (2 R,3 R)- and (2 R,3 S)-3-fluoroprolines

Tetrahedron letters, 2001-01, Vol.42 (4), p.651-653

2001

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Irditoxin, a novel covalently linked heterodimeric three-finger toxin with high taxon-specific neurotoxicity

The FASEB journal, 2009-02, Vol.23 (2), p.534-545

2009

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Structural and functional consequences of the presence of a fourth disulfide bridge in the scorpion short toxins: Solution structure of the potassium channel inhibitor HsTX1

Protein science, 1999-12, Vol.8 (12), p.2672-2685

1999

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Crystal structure of the human urokinase plasminogen activator receptor bound to an antagonist peptide

The EMBO journal, 2005-05, Vol.24 (9), p.1655-1663

2005

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Functional architectures of animal toxins: a clue to drug design?

Isolation of a Tarantula Toxin Specific for a Class of Proton-gated Na+ Channels

Bee Venom Phospholipase A2, a Good "Chauffeur" for Delivering Tumor Antigen to the MHC I and MHC II Peptide-Loading Compartments of the Dendritic Cells: The Case of NY-ESO-1

‘Venomics’ or: The venomous systems genome project

Structural Evidence for a Functional Role of Human Tissue Nonspecific Alkaline Phosphatase in Bone Mineralization

Structural basis for the NAD‐hydrolysis mechanism and the ARTT‐loop plasticity of C3 exoenzymes

HLA-DR Restricted Peptide Candidates for Bee Venom Immunotherapy

Experimentally Based Model of a Complex between a Snake Toxin and the α7 Nicotinic Receptor

Rational Engineering of a Miniprotein That Reproduces the Core of the CD4 Site Interacting with HIV-1 Envelope Glycoprotein

Fine Tuning of the Specificity of an Anti-progesterone Antibody by First and Second Sphere Residue Engineering

A Variable Residue in the Pore of Kv1 Channels Is Critical for the High Affinity of Blockers from Sea Anemones and Scorpions

Scanning the HIV Genome for CD4+ T Cell Epitopes Restricted to HLA-DP4, the Most Prevalent HLA Class II Molecule

Refined Structure of Charybdotoxin: Common Motifs in Scorpion Toxins and Insect Defensins

Improving Escherichia coli Alkaline Phosphatase Efficacy by Additional Mutations inside and outside the Catalytic Pocket

NAD Binding Induces Conformational Changes in Rho ADP-ribosylating Clostridium botulinum C3 Exoenzyme

How Do Short Neurotoxins Bind to a Muscular-type Nicotinic Acetylcholine Receptor?

Practical synthesis of Boc and Fmoc protected 4-fluoro and 4-difluoroprolines from trans-4-hydroxyproline

Dual Expression System Suitable for High-Throughput Fluorescence-Based Screening and Production of Soluble Proteins

Structural features common to intracellularly acting toxins from bacteria

Molecular characterization of the specificity of interactions of various neurotoxins on two distinct nicotinic acetylcholine receptors

Chemical engineering of a three-fingered toxin with anti-α7 neuronal acetylcholine receptor activity

Synthesis of optically pure N-Boc-protected (2 R,3 R)- and (2 R,3 S)-3-fluoroprolines

Irditoxin, a novel covalently linked heterodimeric three-finger toxin with high taxon-specific neurotoxicity

Structural and functional consequences of the presence of a fourth disulfide bridge in the scorpion short toxins: Solution structure of the potassium channel inhibitor HsTX1

Crystal structure of the human urokinase plasminogen activator receptor bound to an antagonist peptide

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