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Doxorubicin in vivo rapidly alters expression and translation of myocardial electron transport chain genes, leads to ATP loss and caspase 3 activation

PloS one, 2010-09, Vol.5 (9), p.e12733

2010

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The generation of HepG2 transmitochondrial cybrids to reveal the role of mitochondrial genotype in idiosyncratic drug-induced liver injury

eLife, 2023-06, Vol.12

2023

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Enhanced hepatic respiratory capacity and altered lipid metabolism support metabolic homeostasis during short-term hypoxic stress

BMC biology, 2021-12, Vol.19 (1), p.265-265, Article 265

2021

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Time to Change: A Systems Pharmacology Approach to Disentangle Mechanisms of Drug-Induced Mitochondrial Toxicity

Pharmacological reviews, 2023-05, Vol.75 (3), p.463-486

2023

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Identification of the Additional Mitochondrial Liabilities of 2-Hydroxyflutamide When Compared With its Parent Compound, Flutamide in HepG2 Cells

Toxicological sciences, 2016-10, Vol.153 (2), p.341-351

2016

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Assessment of the impact of mitochondrial genotype upon drug-induced mitochondrial dysfunction in platelets derived from healthy volunteers

Archives of toxicology, 2021-04, Vol.95 (4), p.1335-1347

2021

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Effects of mid-respiratory chain inhibition on mitochondrial function in vitro and in vivo

Toxicology research (Cambridge), 2016-01, Vol.5 (1), p.136-150

2016

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Pivotal Role for Two Electron Reduction in 2,3-Dimethoxy-1,4-naphthoquinone and 2-Methyl-1,4-naphthoquinone Metabolism and Kinetics in Vivo That Prevents Liver Redox Stress

Chemical research in toxicology, 2009-04, Vol.22 (4), p.717-725

2009

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Effects of mid-respiratory chain inhibition on mitochondrial function in vitro and in vivoElectronic supplementary information (ESI) available. See DOI: 10.1039/c5tx00197h

2015-12

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Effects of mid-respiratory chain inhibition on mitochondrial function in vitro and in vivo† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c5tx00197h

Toxicology research (Cambridge), 2015-09, Vol.5 (1), p.136-150

2015

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Interference of Myb transactivation activity by a conditional dominant negative protein: functional interference in a cytotoxic T-cell line results in G1 arrest

Gene, 1996-12, Vol.182 (1-2), p.123-128

1996

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Interference of Myb transactivation activity by a conditional dominant negative protein: functional interference in a cytotoxic T-cell line results in G 1 arrest

Gene, 1996, Vol.182 (1), p.123-128

1996

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Conditional inhibition of erythroid differentiation by c-Myb/oestrogen receptor fusion proteins

Differentiation (London), 1995-10, Vol.59 (3), p.171-178

1995

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Cardiac isoenzyme values after total joint arthroplasty

Clinical orthopaedics and related research, 1989-05, Vol.242 (242), p.232-240

1989

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Operative Treatment of Acute Hip Fractures: Its Effect on Serum Creatine Kinase, Lactate Dehydrogenase and their Isoenzymes

The journal of trauma, 1989-03, Vol.29 (3), p.375-379

1989

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Clinical Care of Two Patients with Ebola Virus Disease in the United States

The New England journal of medicine, 2014-12, Vol.371 (25), p.2402-2409

2014

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A Disynaptic Relay from Superior Colliculus to Dorsal Stream Visual Cortex in Macaque Monkey

Neuron (Cambridge, Mass.), 2010-01, Vol.65 (2), p.270-279

2010

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ACMG clinical laboratory standards for next-generation sequencing

Genetics in medicine, 2013-09, Vol.15 (9), p.733-747

2013

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Real-time quantification of single RNA translation dynamics in living cells

Science (American Association for the Advancement of Science), 2016-06, Vol.352 (6292), p.1425-1429

2016

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Femoral vascular access for endovascular resuscitation

The journal of trauma and acute care surgery, 2021-10, Vol.91 (4), p.e104-e113

2021

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Promises and pitfalls in implementation science from the perspective of US-based researchers: learning from a pre-mortem

Implementation science : IS, 2022-08, Vol.17 (1), p.1-55, Article 55

2022

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PRISMA-S: an extension to the PRISMA Statement for Reporting Literature Searches in Systematic Reviews

Systematic reviews, 2021-01, Vol.10 (1), p.39-19, Article 39

2021

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Fifteen-Year Outcomes after Monitoring, Surgery, or Radiotherapy for Prostate Cancer

The New England journal of medicine, 2023-04, Vol.388 (17), p.1547-1558

2023

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SGN-CD33A: a novel CD33-targeting antibody–drug conjugate using a pyrrolobenzodiazepine dimer is active in models of drug-resistant AML

Blood, 2013-08, Vol.122 (8), p.1455-1463

2013

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Doxorubicin in vivo rapidly alters expression and translation of myocardial electron transport chain genes, leads to ATP loss and caspase 3 activation

The generation of HepG2 transmitochondrial cybrids to reveal the role of mitochondrial genotype in idiosyncratic drug-induced liver injury

Enhanced hepatic respiratory capacity and altered lipid metabolism support metabolic homeostasis during short-term hypoxic stress

Time to Change: A Systems Pharmacology Approach to Disentangle Mechanisms of Drug-Induced Mitochondrial Toxicity

Identification of the Additional Mitochondrial Liabilities of 2-Hydroxyflutamide When Compared With its Parent Compound, Flutamide in HepG2 Cells

DNDI-6174 is a preclinical candidate for visceral leishmaniasis that targets the cytochrome bc 1

Assessment of the impact of mitochondrial genotype upon drug-induced mitochondrial dysfunction in platelets derived from healthy volunteers

Effects of mid-respiratory chain inhibition on mitochondrial function in vitro and in vivo

Pivotal Role for Two Electron Reduction in 2,3-Dimethoxy-1,4-naphthoquinone and 2-Methyl-1,4-naphthoquinone Metabolism and Kinetics in Vivo That Prevents Liver Redox Stress

Effects of mid-respiratory chain inhibition on mitochondrial function in vitro and in vivoElectronic supplementary information (ESI) available. See DOI: 10.1039/c5tx00197h

Effects of mid-respiratory chain inhibition on mitochondrial function in vitro and in vivo† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c5tx00197h

Interference of Myb transactivation activity by a conditional dominant negative protein: functional interference in a cytotoxic T-cell line results in G1 arrest

Interference of Myb transactivation activity by a conditional dominant negative protein: functional interference in a cytotoxic T-cell line results in G 1 arrest

Conditional inhibition of erythroid differentiation by c-Myb/oestrogen receptor fusion proteins

Cardiac isoenzyme values after total joint arthroplasty

Operative Treatment of Acute Hip Fractures: Its Effect on Serum Creatine Kinase, Lactate Dehydrogenase and their Isoenzymes

Clinical Care of Two Patients with Ebola Virus Disease in the United States

A Disynaptic Relay from Superior Colliculus to Dorsal Stream Visual Cortex in Macaque Monkey

ACMG clinical laboratory standards for next-generation sequencing

Real-time quantification of single RNA translation dynamics in living cells

Femoral vascular access for endovascular resuscitation

Promises and pitfalls in implementation science from the perspective of US-based researchers: learning from a pre-mortem

PRISMA-S: an extension to the PRISMA Statement for Reporting Literature Searches in Systematic Reviews

Fifteen-Year Outcomes after Monitoring, Surgery, or Radiotherapy for Prostate Cancer

SGN-CD33A: a novel CD33-targeting antibody–drug conjugate using a pyrrolobenzodiazepine dimer is active in models of drug-resistant AML

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