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Biofilm Exopolysaccharides of Pathogenic Fungi: Lessons from Bacteria

The Journal of biological chemistry, 2016-06, Vol.291 (24), p.12529-12537

2016

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The molecular mechanism of the type IVa pilus motors

Nature communications, 2017-05, Vol.8 (1), p.15091-15091, Article 15091

2017

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Biosynthesis of the Pseudomonas aeruginosa Extracellular Polysaccharides, Alginate, Pel, and Psl

Frontiers in cellular and infection microbiology, 2011-01, Vol.2, p.167-167

2011

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Gram-negative synthase-dependent exopolysaccharide biosynthetic machines

Current opinion in structural biology, 2018-12, Vol.53, p.32-44

2018

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phage λ major tail protein structure reveals a common evolution for long-tailed phages and the type VI bacterial secretion system

Proceedings of the National Academy of Sciences - PNAS, 2009-03, Vol.106 (11), p.4160-4165

2009

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Pel is a cationic exopolysaccharide that cross-links extracellular DNA in the Pseudomonas aeruginosa biofilm matrix

Proceedings of the National Academy of Sciences - PNAS, 2015-09, Vol.112 (36), p.11353-11358

2015

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Precision-engineering the Pseudomonas aeruginosa genome with two-step allelic exchange

Nature protocols, 2015-11, Vol.10 (11), p.1820-1841

2015

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Molecular mechanism of Aspergillus fumigatus biofilm disruption by fungal and bacterial glycoside hydrolases

The Journal of biological chemistry, 2019-07, Vol.294 (28), p.10760-10772

2019

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A systematic pipeline for classifying bacterial operons reveals the evolutionary landscape of biofilm machineries

PLoS computational biology, 2020-04, Vol.16 (4), p.e1007721

2020

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The Pel and Psl polysaccharides provide Pseudomonas aeruginosa structural redundancy within the biofilm matrix

Environmental microbiology, 2012-08, Vol.14 (8), p.1913-1928

2012

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Deacetylated microbial biofilm exopolysaccharides: It pays to be positive

PLoS pathogens, 2018-12, Vol.14 (12), p.e1007411-e1007411

2018

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The TPR domain of PgaA is a multifunctional scaffold that binds PNAG and modulates PgaB-dependent polymer processing

PLoS pathogens, 2022-08, Vol.18 (8), p.e1010750-e1010750

2022

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Structural and biochemical characterization of the exopolysaccharide deacetylase Agd3 required for Aspergillus fumigatus biofilm formation

Nature communications, 2020-05, Vol.11 (1), p.2450-2450, Article 2450

2020

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Treatment with the Pseudomonas aeruginosa Glycoside Hydrolase PslG Combats Wound Infection by Improving Antibiotic Efficacy and Host Innate Immune Activity

Antimicrobial agents and chemotherapy, 2019-06, Vol.63 (6)

2019

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Structural basis for the O-acetyltransferase function of the extracytoplasmic domain of OatA from Staphylococcus aureus

The Journal of biological chemistry, 2020-06, Vol.295 (24), p.8204-8213

2020

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Microbial glycoside hydrolases as antibiofilm agents with cross-kingdom activity

Proceedings of the National Academy of Sciences - PNAS, 2017-07, Vol.114 (27), p.7124-7129

2017

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Bps polysaccharide of Bordetella pertussis resists antimicrobial peptides by functioning as a dual surface shield and decoy and converts Escherichia coli into a respiratory pathogen

PLoS pathogens, 2022-08, Vol.18 (8), p.e1010764-e1010764

2022

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PelA Deacetylase Activity Is Required for Pel Polysaccharide Synthesis in Pseudomonas aeruginosa

Journal of Bacteriology, 2013-05, Vol.195 (10), p.2329-2339

2013

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Enzymatic modifications of exopolysaccharides enhance bacterial persistence

Frontiers in microbiology, 2015-05, Vol.6, p.471-471

2015

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PelA and PelB proteins form a modification and secretion complex essential for Pel polysaccharide-dependent biofilm formation in Pseudomonas aeruginosa

The Journal of biological chemistry, 2017-11, Vol.292 (47), p.19411-19422

2017

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PgaB orthologues contain a glycoside hydrolase domain that cleaves deacetylated poly-β(1,6)-N-acetylglucosamine and can disrupt bacterial biofilms

PLoS pathogens, 2018-04, Vol.14 (4), p.e1006998

2018

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Galactosaminogalactan (GAG) and its multiple roles in Aspergillus pathogenesis

Virulence, 2019-01, Vol.10 (1), p.976-983

2019

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Ega3 from the fungal pathogen Aspergillus fumigatus is an endo-α-1,4-galactosaminidase that disrupts microbial biofilms

The Journal of biological chemistry, 2019-09, Vol.294 (37), p.13833-13849

2019

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Discovery and characterization of a Gram-positive Pel polysaccharide biosynthetic gene cluster

PLoS pathogens, 2020-04, Vol.16 (4), p.e1008281-e1008281

2020

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Structural basis for alginate secretion across the bacterial outer membrane

Proceedings of the National Academy of Sciences - PNAS, 2011-08, Vol.108 (32), p.13083-13088

2011

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Biofilm Exopolysaccharides of Pathogenic Fungi: Lessons from Bacteria

The molecular mechanism of the type IVa pilus motors

Biosynthesis of the Pseudomonas aeruginosa Extracellular Polysaccharides, Alginate, Pel, and Psl

Gram-negative synthase-dependent exopolysaccharide biosynthetic machines

phage λ major tail protein structure reveals a common evolution for long-tailed phages and the type VI bacterial secretion system

Pel is a cationic exopolysaccharide that cross-links extracellular DNA in the Pseudomonas aeruginosa biofilm matrix

Precision-engineering the Pseudomonas aeruginosa genome with two-step allelic exchange

Molecular mechanism of Aspergillus fumigatus biofilm disruption by fungal and bacterial glycoside hydrolases

A systematic pipeline for classifying bacterial operons reveals the evolutionary landscape of biofilm machineries

The Pel and Psl polysaccharides provide Pseudomonas aeruginosa structural redundancy within the biofilm matrix

Deacetylated microbial biofilm exopolysaccharides: It pays to be positive

The TPR domain of PgaA is a multifunctional scaffold that binds PNAG and modulates PgaB-dependent polymer processing

Structural and biochemical characterization of the exopolysaccharide deacetylase Agd3 required for Aspergillus fumigatus biofilm formation

Treatment with the Pseudomonas aeruginosa Glycoside Hydrolase PslG Combats Wound Infection by Improving Antibiotic Efficacy and Host Innate Immune Activity

Structural basis for the O-acetyltransferase function of the extracytoplasmic domain of OatA from Staphylococcus aureus

Microbial glycoside hydrolases as antibiofilm agents with cross-kingdom activity

Bps polysaccharide of Bordetella pertussis resists antimicrobial peptides by functioning as a dual surface shield and decoy and converts Escherichia coli into a respiratory pathogen

PelA Deacetylase Activity Is Required for Pel Polysaccharide Synthesis in Pseudomonas aeruginosa

Enzymatic modifications of exopolysaccharides enhance bacterial persistence

PelA and PelB proteins form a modification and secretion complex essential for Pel polysaccharide-dependent biofilm formation in Pseudomonas aeruginosa

PgaB orthologues contain a glycoside hydrolase domain that cleaves deacetylated poly-β(1,6)-N-acetylglucosamine and can disrupt bacterial biofilms

Galactosaminogalactan (GAG) and its multiple roles in Aspergillus pathogenesis

Ega3 from the fungal pathogen Aspergillus fumigatus is an endo-α-1,4-galactosaminidase that disrupts microbial biofilms

Discovery and characterization of a Gram-positive Pel polysaccharide biosynthetic gene cluster

Structural basis for alginate secretion across the bacterial outer membrane

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