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Discovery of a series of novel 5H-pyrrolo[2,3-b]pyrazine-2-phenyl ethers, as potent JAK3 kinase inhibitors

Bioorganic & medicinal chemistry letters, 2013-05, Vol.23 (9), p.2522-2526

2013

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Molecular pharmacology and antitumor activity of palmarumycin-based inhibitors of thioredoxin reductase

Molecular cancer therapeutics, 2006-03, Vol.5 (3), p.630-636

2006

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Natural product based inhibitors of the thioredoxin-thioredoxin reductase system

Organic & biomolecular chemistry, 2004-06, Vol.2 (11), p.1651-1658

2004

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Synthesis of Highly Oxygenated Dinaphthyl Ethers via SNAr Reactions Promoted by Barton's Base

Organic letters, 2003-04, Vol.5 (7), p.1155-1158

2003

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Dibenzazepines and dibenzoxazepines as sodium channel blockers

Bioorganic & medicinal chemistry letters, 2015-01, Vol.25 (1), p.43-47

2015

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N-Aryl azacycles as novel sodium channel blockers

Bioorganic & medicinal chemistry letters, 2015-01, Vol.25 (1), p.48-52

2015

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Pyrrolopyrazines as Selective Spleen Tyrosine Kinase Inhibitors

Journal of medicinal chemistry, 2013-02, Vol.56 (4), p.1677-1692

2013

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Strategic use of conformational bias and structure based design to identify potent JAK3 inhibitors with improved selectivity against the JAK family and the kinome

Bioorganic & medicinal chemistry letters, 2013-05, Vol.23 (9), p.2793-2800

2013

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Cycloaddition Chemistry of 2-Vinyl-Substituted Indoles and Related Heteroaromatic Systems

Journal of organic chemistry, 2005-03, Vol.70 (6), p.2206-2218

2005

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Design, synthesis, and biological evaluation of new monoamine reuptake inhibitors with potential therapeutic utility in depression and pain

Bioorganic & medicinal chemistry letters, 2010-09, Vol.20 (18), p.5559-5566

2010

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Novel 3,3-disubstituted pyrrolidines as selective triple serotonin/norepinephrine/dopamine reuptake inhibitors

Bioorganic & medicinal chemistry, 2008-12, Vol.18 (23), p.6062-6066

2008

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Intramolecular Amidofuran Cycloadditions across an Indole π-Bond: An Efficient Approach to the Aspidosperma and Strychnos ABCE Core

Organic letters, 2002-12, Vol.4 (26), p.4643-4645

2002

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A New Strategy toward Indole Alkaloids Involving an Intramolecular Cycloaddition/Rearrangement Cascade

Journal of organic chemistry, 2004-05, Vol.69 (11), p.3735-3745

2004

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A New Construct of the cis-3a-Aryloctahydroindole Skeleton via the [4+2] Cycloaddition of Furanyl Carbamates

Heterocycles, 2002-11, Vol.58 (1), p.227

2002

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Influence of Ground-State Conformations on the Intramolecular Amidofuran Diels−Alder Reaction

Organic letters, 2002-02, Vol.4 (4), p.473-476

2002

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Synthesis and biological activity of prodrug inhibitors of the thioredoxin-thioredoxin reductase system

Organic & biomolecular chemistry, 2005-11, Vol.3 (21), p.3880-3882

2005

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Synthesis of Azapolycyclic Systems via the Intramolecular [4 + 2] Cycloaddition Chemistry of 2-(Alkylthio)-5-amidofurans

Journal of organic chemistry, 2002-05, Vol.67 (10), p.3412-3424

2002

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Application of the tandem thionium/N-acyliminium ion cascade toward heterocyclic synthesis

Journal of the Brazilian Chemical Society, 2001-10, Vol.12 (5), p.571-585

2001

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Formal Total Synthesis of (±)-γ-Lycorane and (±)-1-Deoxylycorine Using the [4+2]-Cycloaddition/Rearrangement Cascade of Furanyl Carbamates

Journal of organic chemistry, 2001-03, Vol.66 (5), p.1716-1724

2001

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Synthesis of Highly Oxygenated Dinaphthyl Ethers via S N Ar Reactions Promoted by Barton's Base

Organic letters, 2003-04, Vol.5 (7), p.1155-1158

2003

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Linked Pummerer-Mannich Ion Cyclizations for Heterocyclic Chemistry

Synlett, 2002, Vol.2002 (6), p.851-862

2002

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Intramolecular [4+2]-cycloaddition reactions of cyclic 2-thiomethyl-5-amidofurans

Tetrahedron letters, 2000-12, Vol.41 (49), p.9387-9391

2000

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PREPARATION AND DIELS-ALDER REACTION OF A 2-AMIDO SUBSTITUTED FURAN: tert-BUTYL 3a-METHYL-5-OXO-2,3,3a,4,5,6-HEXAHYDROINDOLE-1-CARBOXYLATE

Organic syntheses, 2002, Vol.78, p.202

2002

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Synthesis of Highly Oxygenated Dinaphthyl Ethers via SNAr Reactions Promoted by Barton′s Base

ChemInform, 2003-08, Vol.34 (32), p.no-no

2003

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Synthesis of Highly Oxygenated Dinaphthyl Ethers via S N Ar Reactions Promoted by Barton′s Base

ChemInform, 2003-08, Vol.34 (32)

2003

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Discovery of a series of novel 5H-pyrrolo[2,3-b]pyrazine-2-phenyl ethers, as potent JAK3 kinase inhibitors

Molecular pharmacology and antitumor activity of palmarumycin-based inhibitors of thioredoxin reductase

Natural product based inhibitors of the thioredoxin-thioredoxin reductase system

Synthesis of Highly Oxygenated Dinaphthyl Ethers via SNAr Reactions Promoted by Barton's Base

Dibenzazepines and dibenzoxazepines as sodium channel blockers

N-Aryl azacycles as novel sodium channel blockers

Pyrrolopyrazines as Selective Spleen Tyrosine Kinase Inhibitors

Strategic use of conformational bias and structure based design to identify potent JAK3 inhibitors with improved selectivity against the JAK family and the kinome

Cycloaddition Chemistry of 2-Vinyl-Substituted Indoles and Related Heteroaromatic Systems

Design, synthesis, and biological evaluation of new monoamine reuptake inhibitors with potential therapeutic utility in depression and pain

Novel 3,3-disubstituted pyrrolidines as selective triple serotonin/norepinephrine/dopamine reuptake inhibitors

Intramolecular Amidofuran Cycloadditions across an Indole π-Bond: An Efficient Approach to the Aspidosperma and Strychnos ABCE Core

A New Strategy toward Indole Alkaloids Involving an Intramolecular Cycloaddition/Rearrangement Cascade

A New Construct of the cis-3a-Aryloctahydroindole Skeleton via the [4+2] Cycloaddition of Furanyl Carbamates

Influence of Ground-State Conformations on the Intramolecular Amidofuran Diels−Alder Reaction

Synthesis and biological activity of prodrug inhibitors of the thioredoxin-thioredoxin reductase system

Synthesis of Azapolycyclic Systems via the Intramolecular [4 + 2] Cycloaddition Chemistry of 2-(Alkylthio)-5-amidofurans

Application of the tandem thionium/N-acyliminium ion cascade toward heterocyclic synthesis

Formal Total Synthesis of (±)-γ-Lycorane and (±)-1-Deoxylycorine Using the [4+2]-Cycloaddition/Rearrangement Cascade of Furanyl Carbamates

Synthesis of Highly Oxygenated Dinaphthyl Ethers via S N Ar Reactions Promoted by Barton's Base

Linked Pummerer-Mannich Ion Cyclizations for Heterocyclic Chemistry

Intramolecular [4+2]-cycloaddition reactions of cyclic 2-thiomethyl-5-amidofurans

PREPARATION AND DIELS-ALDER REACTION OF A 2-AMIDO SUBSTITUTED FURAN: tert-BUTYL 3a-METHYL-5-OXO-2,3,3a,4,5,6-HEXAHYDROINDOLE-1-CARBOXYLATE

Synthesis of Highly Oxygenated Dinaphthyl Ethers via SNAr Reactions Promoted by Barton′s Base

Synthesis of Highly Oxygenated Dinaphthyl Ethers via S N Ar Reactions Promoted by Barton′s Base

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