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Lectin Pathway Mediates Complement Activation by SARS-CoV-2 Proteins

Frontiers in immunology, 2021-07, Vol.12, p.714511-714511

2021

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The lectin pathway of complement activation is a critical component of the innate immune response to pneumococcal infection

PLoS pathogens, 2012-07, Vol.8 (7), p.e1002793-e1002793

2012

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The Pneumococcal Surface Proteins PspA and PspC Sequester Host C4-Binding Protein To Inactivate Complement C4b on the Bacterial Surface

Infection and immunity, 2019-01, Vol.87 (1)

2019

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Targeting of mannan-binding lectin-associated serine protease-2 confers protection from myocardial and gastrointestinal ischemia/reperfusion injury

Proceedings of the National Academy of Sciences - PNAS, 2011-05, Vol.108 (18), p.7523-7528

2011

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Inhibition of the lectin pathway of complement activation reduces LPS-induced acute respiratory distress syndrome in mice

Frontiers in immunology, 2023, Vol.14, p.1192767-1192767

2023

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Low-dose recombinant properdin provides substantial protection against Streptococcus pneumoniae and Neisseria meningitidis infection

Proceedings of the National Academy of Sciences - PNAS, 2014-04, Vol.111 (14), p.5301-5306

2014

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Secondary Complement Deficiency Impairs Anti-Microbial Immunity to Klebsiella pneumoniae and Staphylococcus aureus During Severe Acute COVID-19

Frontiers in immunology, 2022-04, Vol.13, p.841759

2022

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Inhibition of the lectin pathway of complement ameliorates hypocomplementemia and restores serum bactericidal activity in patients with severe COVID‐19

Clinical and translational medicine, 2022-07, Vol.12 (7), p.e980-n/a

2022

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L-Ficolin Specifically Binds to Lipoteichoic Acid, a Cell Wall Constituent of Gram-Positive Bacteria, and Activates the Lectin Pathway of Complement

The Journal of immunology (1950), 2004-01, Vol.172 (2), p.1198-1202

2004

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Small Mannose-Binding Lectin-Associated Protein Plays a Regulatory Role in the Lectin Complement Pathway

Journal of Immunology, 2006-12, Vol.177 (12), p.8626-8632

2006

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Inhibition of the Lectin Pathway of Complement Activation Reduces Acute Respiratory Distress Syndrome Severity in a Mouse Model of SARS-CoV-2 Infection

The Journal of infectious diseases, 2024-03, Vol.229 (3), p.680-690

2024

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Differential Expression of the Murine Mannose-Binding Lectins A and C in Lymphoid and Nonlymphoid Organs and Tissues

The Journal of immunology (1950), 2003-02, Vol.170 (3), p.1462-1465

2003

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Two Constituents of the Initiation Complex of the Mannan-Binding Lectin Activation Pathway of Complement Are Encoded by a Single Structural Gene

The Journal of immunology (1950), 1999-03, Vol.162 (6), p.3481-3490

1999

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Microglial activation and increased synthesis of complement component C1q precedes blood–brain barrier dysfunction in rats

Molecular immunology, 2004, Vol.40 (10), p.709-716

2004

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Antibody‐mediated activation of the classical pathway of complement may compensate for mannose‐binding lectin deficiency

European Journal of Immunology, 2004-09, Vol.34 (9), p.2589-2598

2004

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Deficiency in mannose-binding lectin-associated serine protease-2 does not increase susceptibility to Trypanosoma cruzi infection

The American journal of tropical medicine and hygiene, 2015-02, Vol.92 (2), p.320-324

2015

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Neuronal expression of fractalkine in the presence and absence of inflammation

FEBS letters, 1998-11, Vol.439 (3), p.203-207

1998

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Use of recombinant calreticulin and cercarial transformation fluid (CTF) in the serodiagnosis of Schistosoma mansoni

Immunobiology (1979), 2011-03, Vol.216 (3), p.379-385

2011

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Absence of the lectin activation pathway of complement does not increase susceptibility to Pseudomonas aeruginosa infections

Immunobiology (1979), 2012-02, Vol.217 (2), p.272-280

2012

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The Rat and Mouse Homologues of MASP-2 and MAp19, components of the Lectin Activation Pathway of Complement

The Journal of immunology (1950), 1999-12, Vol.163 (12), p.6848-6859

1999

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Composition of the Lectin Pathway of Complement in Gallus gallus: Absence of Mannan-Binding Lectin-Associated Serine Protease-1 in Birds

The Journal of immunology (1950), 2005-04, Vol.174 (8), p.4998-5006

2005

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Linkage of Inflammatory Bowel Disease to Human Chromosome 6p

American journal of human genetics, 1999-12, Vol.65 (6), p.1647-1655

1999

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Reduced serum L-ficolin in paediatric patients with recurrent respiratory infection

Molecular immunology, 2007-09, Vol.44 (16), p.3979-3979

2007

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Decoupling of Carbohydrate Binding and MASP-2 Autoactivation in Variant Mannose-Binding Lectins Associated with Immunodeficiency

Journal of Immunology, 2005-11, Vol.175 (10), p.6846-6851

2005

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Organization of the MASP2 locus and its expression profile in mouse and rat

Mammalian genome, 2004-11, Vol.15 (11), p.887-900

2004

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Lectin Pathway Mediates Complement Activation by SARS-CoV-2 Proteins

The lectin pathway of complement activation is a critical component of the innate immune response to pneumococcal infection

The Pneumococcal Surface Proteins PspA and PspC Sequester Host C4-Binding Protein To Inactivate Complement C4b on the Bacterial Surface

Targeting of mannan-binding lectin-associated serine protease-2 confers protection from myocardial and gastrointestinal ischemia/reperfusion injury

Inhibition of the lectin pathway of complement activation reduces LPS-induced acute respiratory distress syndrome in mice

Low-dose recombinant properdin provides substantial protection against Streptococcus pneumoniae and Neisseria meningitidis infection

Secondary Complement Deficiency Impairs Anti-Microbial Immunity to Klebsiella pneumoniae and Staphylococcus aureus During Severe Acute COVID-19

Inhibition of the lectin pathway of complement ameliorates hypocomplementemia and restores serum bactericidal activity in patients with severe COVID‐19

L-Ficolin Specifically Binds to Lipoteichoic Acid, a Cell Wall Constituent of Gram-Positive Bacteria, and Activates the Lectin Pathway of Complement

Small Mannose-Binding Lectin-Associated Protein Plays a Regulatory Role in the Lectin Complement Pathway

Inhibition of the Lectin Pathway of Complement Activation Reduces Acute Respiratory Distress Syndrome Severity in a Mouse Model of SARS-CoV-2 Infection

Differential Expression of the Murine Mannose-Binding Lectins A and C in Lymphoid and Nonlymphoid Organs and Tissues

Two Constituents of the Initiation Complex of the Mannan-Binding Lectin Activation Pathway of Complement Are Encoded by a Single Structural Gene

Microglial activation and increased synthesis of complement component C1q precedes blood–brain barrier dysfunction in rats

Antibody‐mediated activation of the classical pathway of complement may compensate for mannose‐binding lectin deficiency

Deficiency in mannose-binding lectin-associated serine protease-2 does not increase susceptibility to Trypanosoma cruzi infection

Neuronal expression of fractalkine in the presence and absence of inflammation

Use of recombinant calreticulin and cercarial transformation fluid (CTF) in the serodiagnosis of Schistosoma mansoni

Absence of the lectin activation pathway of complement does not increase susceptibility to Pseudomonas aeruginosa infections

The Rat and Mouse Homologues of MASP-2 and MAp19, components of the Lectin Activation Pathway of Complement

Composition of the Lectin Pathway of Complement in Gallus gallus: Absence of Mannan-Binding Lectin-Associated Serine Protease-1 in Birds

Linkage of Inflammatory Bowel Disease to Human Chromosome 6p

Reduced serum L-ficolin in paediatric patients with recurrent respiratory infection

Decoupling of Carbohydrate Binding and MASP-2 Autoactivation in Variant Mannose-Binding Lectins Associated with Immunodeficiency

Organization of the MASP2 locus and its expression profile in mouse and rat

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