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EPAC and PKA allow cAMP dual control over DNA-PK nuclear translocation

Proceedings of the National Academy of Sciences - PNAS, 2008-09, Vol.105 (35), p.12791-12796

2008

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Cyclic AMP Phosphodiesterase 4D (PDE4D) Tethers EPAC1 in a Vascular Endothelial Cadherin (VE-Cad)-based Signaling Complex and Controls cAMP-mediated Vascular Permeability

The Journal of biological chemistry, 2010-10, Vol.285 (44), p.33614-33622

2010

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Scanning peptide array analyses identify overlapping binding sites for the signalling scaffold proteins, beta-arrestin and RACK1, in cAMP-specific phosphodiesterase PDE4D5

Biochemical journal, 2006-08, Vol.398 (1), p.23-36

2006

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Tyrosine 302 in RACK1 Is Essential for Insulin-like Growth Factor-I-mediated Competitive Binding of PP2A and β1 Integrin and for Tumor Cell Proliferation and Migration

The Journal of biological chemistry, 2008-08, Vol.283 (34), p.22952-22961

2008

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The regulation of biofilm development by quorum sensing in Aeromonas hydrophila

Environmental microbiology, 2002-01, Vol.4 (1), p.18-28

2002

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p75 neurotrophin receptor regulates tissue fibrosis through inhibition of plasminogen activation via a PDE4/cAMP/PKA pathway

The Journal of cell biology, 2007-06, Vol.177 (6), p.1119-1132

2007

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Dynamic Regulation, Desensitization, and Cross-talk in Discrete Subcellular Microdomains during β2-Adrenoceptor and Prostanoid Receptor cAMP Signaling

The Journal of biological chemistry, 2007-11, Vol.282 (47), p.34235-34249

2007

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PGE(1) stimulation of HEK293 cells generates multiple contiguous domains with different [cAMP]: role of compartmentalized phosphodiesterases

The Journal of cell biology, 2006-11, Vol.175 (3), p.441-451

2006

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In cardiac myocytes, cAMP elevation triggers the down-regulation of transcripts and promoter activity for cyclic AMP phosphodiesterase-4A10 (PDE4A10)

Cellular signalling, 2008-11, Vol.20 (11), p.2071-2083

2008

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PGE₁ stimulation of HEK293 cells generates multiple contiguous domains with different [cAMP]: role of compartmentalized phosphodiesterases

The Journal of cell biology, 2006-11, Vol.175 (3), p.441-451

2006

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MEK1 Binds Directly to βArrestin1, Influencing Both Its Phosphorylation by ERK and the Timing of Its Isoprenaline-stimulated Internalization

The Journal of biological chemistry, 2009-04, Vol.284 (17), p.11425-11435

2009

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Quorum sensing-dependent regulation and blockade of exoprotease production in Aeromonas hydrophila

Infection and Immunity, 1999-10, Vol.67 (10), p.5192-5199

1999

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In resting COS1 cells a dominant negative approach shows that specific, anchored PDE4 cAMP phosphodiesterase isoforms gate the activation, by basal cyclic AMP production, of AKAP-tethered protein kinase A type II located in the centrosomal region

Cellular signalling, 2005-09, Vol.17 (9), p.1158-1173

2005

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Phosphodiesterase-4 influences the PKA phosphorylation status and membrane translocation of G-protein receptor kinase 2 (GRK2) in HEK-293β2 cells and cardiac myocytes

Biochemical journal, 2006-03, Vol.394 (2), p.427-435

2006

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Intracellular Targeting of Phosphodiesterase‐4 Underpins Compartmentalized cAMP Signaling

Current Topics in Developmental Biology, 2006, Vol.75, p.225-259

2006

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Aeromonas hydrophila LuxR homologue AhyR regulates the N-acyl homoserine lactone synthase, AhyI positively and negatively in a growth phase-dependent manner

FEMS microbiology letters, 2004-12, Vol.241 (1), p.109-117

2004

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Reduced PDE4 expression and activity contributes to enhanced catecholamine-induced cAMP accumulation in adipocytes from FOXC2 transgenic mice

FEBS letters, 2006-07, Vol.580 (17), p.4126-4130

2006

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Expression, intracellular distribution and basis for lack of catalytic activity of the PDE4A7 isoform encoded by the human PDE4A cAMP-specific phosphodiesterase gene

Biochemical journal, 2004-06, Vol.380 (Pt 2), p.371-384

2004

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RNA Silencing Identifies PDE4D5 as the Functionally Relevant cAMP Phosphodiesterase Interacting with βArrestin to Control the Protein Kinase A/AKAP79-mediated Switching of the β2-Adrenergic Receptor to Activation of ERK in HEK293B2 Cells

The Journal of biological chemistry, 2005-09, Vol.280 (39), p.33178-33189

2005

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Electrospray ionization mass spectrometry of semduramicin and other polyether ionophores

Analytical chemistry (Washington), 1991-09, Vol.63 (17), p.1789-1794

1991

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Residue depletion studies on danofloxacin in the chicken

Journal of agricultural and food chemistry, 1994-02, Vol.42 (2), p.289-294

1994

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Tyrosine 302 in RACK1 is essential for insulin-like growth factor-I-mediated competitive binding of PP2A and beta1 integrin and for tumor cell proliferation and migration

The Journal of biological chemistry, 2008-08, Vol.283 (34), p.22952-22961

2008

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Tyrosine 302 in RACK1 Is Essential for Insulin-like Growth Factor-I-mediated Competitive Binding of PP2A and Î²1 Integrin and for Tumor Cell Proliferation and Migration

The Journal of biological chemistry, 2008-08, Vol.283 (34), p.22952

2008

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MEK1 binds directly to βarrestin1, influencing both its phosphorylation by ERK and the timing of its isoprenaline-stimulated internalization

The Journal of biological chemistry, 2009-12, Vol.284 (52), p.36720-36720

2009

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MEK1 Binds Directly to Î²Arrestin1, Influencing Both Its Phosphorylation by ERK and the Timing of Its Isoprenaline-stimulated Internalization

The Journal of biological chemistry, 2009-04, Vol.284 (17), p.11425

2009

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EPAC and PKA allow cAMP dual control over DNA-PK nuclear translocation

Cyclic AMP Phosphodiesterase 4D (PDE4D) Tethers EPAC1 in a Vascular Endothelial Cadherin (VE-Cad)-based Signaling Complex and Controls cAMP-mediated Vascular Permeability

Scanning peptide array analyses identify overlapping binding sites for the signalling scaffold proteins, beta-arrestin and RACK1, in cAMP-specific phosphodiesterase PDE4D5

Tyrosine 302 in RACK1 Is Essential for Insulin-like Growth Factor-I-mediated Competitive Binding of PP2A and β1 Integrin and for Tumor Cell Proliferation and Migration

The regulation of biofilm development by quorum sensing in Aeromonas hydrophila

p75 neurotrophin receptor regulates tissue fibrosis through inhibition of plasminogen activation via a PDE4/cAMP/PKA pathway

Dynamic Regulation, Desensitization, and Cross-talk in Discrete Subcellular Microdomains during β2-Adrenoceptor and Prostanoid Receptor cAMP Signaling

PGE(1) stimulation of HEK293 cells generates multiple contiguous domains with different [cAMP]: role of compartmentalized phosphodiesterases

In cardiac myocytes, cAMP elevation triggers the down-regulation of transcripts and promoter activity for cyclic AMP phosphodiesterase-4A10 (PDE4A10)

PGE₁ stimulation of HEK293 cells generates multiple contiguous domains with different [cAMP]: role of compartmentalized phosphodiesterases

MEK1 Binds Directly to βArrestin1, Influencing Both Its Phosphorylation by ERK and the Timing of Its Isoprenaline-stimulated Internalization

Quorum sensing-dependent regulation and blockade of exoprotease production in Aeromonas hydrophila

In resting COS1 cells a dominant negative approach shows that specific, anchored PDE4 cAMP phosphodiesterase isoforms gate the activation, by basal cyclic AMP production, of AKAP-tethered protein kinase A type II located in the centrosomal region

Phosphodiesterase-4 influences the PKA phosphorylation status and membrane translocation of G-protein receptor kinase 2 (GRK2) in HEK-293β2 cells and cardiac myocytes

Intracellular Targeting of Phosphodiesterase‐4 Underpins Compartmentalized cAMP Signaling

Aeromonas hydrophila LuxR homologue AhyR regulates the N-acyl homoserine lactone synthase, AhyI positively and negatively in a growth phase-dependent manner

Reduced PDE4 expression and activity contributes to enhanced catecholamine-induced cAMP accumulation in adipocytes from FOXC2 transgenic mice

Expression, intracellular distribution and basis for lack of catalytic activity of the PDE4A7 isoform encoded by the human PDE4A cAMP-specific phosphodiesterase gene

RNA Silencing Identifies PDE4D5 as the Functionally Relevant cAMP Phosphodiesterase Interacting with βArrestin to Control the Protein Kinase A/AKAP79-mediated Switching of the β2-Adrenergic Receptor to Activation of ERK in HEK293B2 Cells

Electrospray ionization mass spectrometry of semduramicin and other polyether ionophores

Residue depletion studies on danofloxacin in the chicken

Tyrosine 302 in RACK1 is essential for insulin-like growth factor-I-mediated competitive binding of PP2A and beta1 integrin and for tumor cell proliferation and migration

Tyrosine 302 in RACK1 Is Essential for Insulin-like Growth Factor-I-mediated Competitive Binding of PP2A and Î²1 Integrin and for Tumor Cell Proliferation and Migration

MEK1 binds directly to βarrestin1, influencing both its phosphorylation by ERK and the timing of its isoprenaline-stimulated internalization

MEK1 Binds Directly to Î²Arrestin1, Influencing Both Its Phosphorylation by ERK and the Timing of Its Isoprenaline-stimulated Internalization

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