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Regulation of learning and memory by meningeal immunity: a key role for IL-4

The Journal of experimental medicine, 2010-05, Vol.207 (5), p.1067-1080

2010

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Mechanism of sphingosine 1-phosphate clearance from blood

Biochemical journal, 2020-03, Vol.477 (5), p.925-935

2020

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Sphingosine kinase type 2 inhibition elevates circulating sphingosine 1-phosphate

Biochemical journal, 2012-10, Vol.447 (1), p.149-157

2012

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Discovery of In Vivo Active Sphingosine-1-phosphate Transporter (Spns2) Inhibitors

Journal of medicinal chemistry, 2022-06, Vol.65 (11), p.7656-7681

2022

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Sphingosine 1-phosphate receptor 3 regulates recruitment of anti-inflammatory monocytes to microvessels during implant arteriogenesis

Proceedings of the National Academy of Sciences - PNAS, 2013-08, Vol.110 (34), p.13785-13790

2013

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Structure−Activity Relationship Studies and in Vivo Activity of Guanidine-Based Sphingosine Kinase Inhibitors: Discovery of SphK1- and SphK2-Selective Inhibitors

Journal of medicinal chemistry, 2015-02, Vol.58 (4), p.1879-1899

2015

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Sphingosine 1-phosphate signaling in perivascular cells enhances inflammation and fibrosis in the kidney

Science translational medicine, 2022-08, Vol.14 (658), p.eabj2681

2022

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Acid sphingomyelinase is activated in sickle cell erythrocytes and contributes to inflammatory microparticle generation in SCD

Blood, 2014-09, Vol.124 (12), p.1941-1950

2014

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Immunosuppressive and Anti-angiogenic Sphingosine 1-Phosphate Receptor-1 Agonists Induce Ubiquitinylation and Proteasomal Degradation of the Receptor

The Journal of biological chemistry, 2007-03, Vol.282 (12), p.9082-9089

2007

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Building a better sphingosine kinase-1 inhibitor

Biochemical journal, 2012-05, Vol.444 (1), p.e1-e2

Lynch, Kevin R

2012

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Sphingosine-1-Phosphate Induces an Antiinflammatory Phenotype in Macrophages

Circulation research, 2008-04, Vol.102 (8), p.950-958

2008

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Sphingosine 1-phosphate receptor-1 enhances mitochondrial function and reduces cisplatin-induced tubule injury

Journal of the American Society of Nephrology, 2015-04, Vol.26 (4), p.908-925

2015

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The Immune Modulator FTY720 Targets Sphingosine 1-Phosphate Receptors

The Journal of biological chemistry, 2002-06, Vol.277 (24), p.21453-21457

2002

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Dendritic cell sphingosine 1-phosphate receptor-3 regulates Th1-Th2 polarity in kidney ischemia-reperfusion injury

The Journal of immunology (1950), 2012-09, Vol.189 (5), p.2584-2596

2012

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Lipid phosphate phosphohydrolase type 1 (LPP1) degrades extracellular lysophosphatidic acid in vivo

Biochemical journal, 2009-05, Vol.419 (3), p.611-618

2009

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Decreased peritoneal ovarian cancer growth in mice lacking expression of lipid phosphate phosphohydrolase 1

PloS one, 2015-03, Vol.10 (3), p.e0120071

2015

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FTY720: targeting G-protein-coupled receptors for sphingosine 1-phosphate in transplantation and autoimmunity

Current Opinion in Immunology, 2002-10, Vol.14 (5), p.569-575

2002

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Brown recluse spider (Loxosceles reclusa) venom phospholipase D (PLD) generates lysophosphatidic acid (LPA)

Biochemical journal, 2005-10, Vol.391 (Pt 2), p.317-323

2005

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Sphingosine kinase type 1 inhibition reveals rapid turnover of circulating sphingosine 1-phosphate

Biochemical journal, 2011-12, Vol.440 (3), p.345-353

2011

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Assay of Sphingosine 1-phosphate Transporter Spinster Homolog 2 (Spns2) Inhibitors

SLAS discovery, 2023-09, Vol.28 (6), p.284-287

2023

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Sphingosine 1-Phosphate Analogs as Receptor Antagonists

The Journal of biological chemistry, 2005-03, Vol.280 (11), p.9833-9841

2005

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Activation of Sphingosine-1-Phosphate 1 Receptor in the Proximal Tubule Protects Against Ischemia-Reperfusion Injury

Journal of the American Society of Nephrology, 2010-06, Vol.21 (6), p.955-965

2010

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Chronic sphingosine 1-phosphate 1 receptor activation attenuates early-stage diabetic nephropathy independent of lymphocytes

Kidney international, 2011-05, Vol.79 (10), p.1090-1098

2011

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Photoacoustic microscopy reveals the hemodynamic basis of sphingosine 1-phosphate-induced neuroprotection against ischemic stroke

Theranostics, 2018-01, Vol.8 (22), p.6111-6120

2018

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Sphingosine-1-phosphate receptor subtypes differentially regulate smooth muscle cell phenotype

Arteriosclerosis, thrombosis, and vascular biology, 2008-08, Vol.28 (8), p.1454

2008

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Regulation of learning and memory by meningeal immunity: a key role for IL-4

Mechanism of sphingosine 1-phosphate clearance from blood

Sphingosine kinase type 2 inhibition elevates circulating sphingosine 1-phosphate

Discovery of In Vivo Active Sphingosine-1-phosphate Transporter (Spns2) Inhibitors

Sphingosine 1-phosphate receptor 3 regulates recruitment of anti-inflammatory monocytes to microvessels during implant arteriogenesis

Structure−Activity Relationship Studies and in Vivo Activity of Guanidine-Based Sphingosine Kinase Inhibitors: Discovery of SphK1- and SphK2-Selective Inhibitors

Sphingosine 1-phosphate signaling in perivascular cells enhances inflammation and fibrosis in the kidney

Acid sphingomyelinase is activated in sickle cell erythrocytes and contributes to inflammatory microparticle generation in SCD

Immunosuppressive and Anti-angiogenic Sphingosine 1-Phosphate Receptor-1 Agonists Induce Ubiquitinylation and Proteasomal Degradation of the Receptor

Building a better sphingosine kinase-1 inhibitor

Sphingosine-1-Phosphate Induces an Antiinflammatory Phenotype in Macrophages

Sphingosine 1-phosphate receptor-1 enhances mitochondrial function and reduces cisplatin-induced tubule injury

The Immune Modulator FTY720 Targets Sphingosine 1-Phosphate Receptors

Dendritic cell sphingosine 1-phosphate receptor-3 regulates Th1-Th2 polarity in kidney ischemia-reperfusion injury

Lipid phosphate phosphohydrolase type 1 (LPP1) degrades extracellular lysophosphatidic acid in vivo

Decreased peritoneal ovarian cancer growth in mice lacking expression of lipid phosphate phosphohydrolase 1

FTY720: targeting G-protein-coupled receptors for sphingosine 1-phosphate in transplantation and autoimmunity

Brown recluse spider (Loxosceles reclusa) venom phospholipase D (PLD) generates lysophosphatidic acid (LPA)

Sphingosine kinase type 1 inhibition reveals rapid turnover of circulating sphingosine 1-phosphate

Assay of Sphingosine 1-phosphate Transporter Spinster Homolog 2 (Spns2) Inhibitors

Sphingosine 1-Phosphate Analogs as Receptor Antagonists

Activation of Sphingosine-1-Phosphate 1 Receptor in the Proximal Tubule Protects Against Ischemia-Reperfusion Injury

Chronic sphingosine 1-phosphate 1 receptor activation attenuates early-stage diabetic nephropathy independent of lymphocytes

Photoacoustic microscopy reveals the hemodynamic basis of sphingosine 1-phosphate-induced neuroprotection against ischemic stroke

Sphingosine-1-phosphate receptor subtypes differentially regulate smooth muscle cell phenotype

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