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A small molecule CRTH2 antagonist inhibits FITC-induced allergic cutaneous inflammation

International immunology, 2009-01, Vol.21 (1), p.81-93

2009

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A new perspective of cannabinoid 1 receptor antagonists: approaches toward peripheral CB1R blockers without crossing the blood-brain barrier

Current topics in medicinal chemistry, 2011-06, Vol.11 (12), p.1421-1429

2011

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General Approach to 2,3-Dibenzyl-γ-butyrolactone Lignans: Application to the Total Synthesis of (±)-5′-Methoxyyatein, (±)-5′-Methoxyclusin, and (±)-4′-Hydroxycubebinone

European Journal of Organic Chemistry, 2010-06, Vol.2010 (18), p.3473-3480

2010

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Murine bone marrow-derived mast cells express chemoattractant receptor-homologous molecule expressed on T-helper class 2 cells (CRTh2)

International immunology, 2009-06, Vol.21 (6), p.621-632

2009

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Antagonism of CRTH2 ameliorates chronic epicutaneous sensitization-induced inflammation by multiple mechanisms

International immunology, 2009-01, Vol.21 (1), p.1-17

2009

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MAP3K19 Is a Novel Regulator of TGF-β Signaling That Impacts Bleomycin-Induced Lung Injury and Pulmonary Fibrosis

PloS one, 2016-05, Vol.11 (5), p.e0154874

2016

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Targeting MAP3K19 prevents human lung myofibroblast activation both in vitro and in a humanized SCID model of idiopathic pulmonary fibrosis

Scientific reports, 2019-12, Vol.9 (1), p.19796-10, Article 19796

2019

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MAP3K19 Is Overexpressed in COPD and Is a Central Mediator of Cigarette Smoke-Induced Pulmonary Inflammation and Lower Airway Destruction

PloS one, 2016-12, Vol.11 (12), p.e0167169-e0167169

2016

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Application of the Barton photochemical reaction in the synthesis of 1-dethia-3-aza-1-carba-2-oxacephem: a novel agent against resistant pathogenic microorganisms

Organic & biomolecular chemistry, 2003-01, Vol.1 (14), p.2461-2467

2003

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The first total synthesis of xenitorins B and C: assignment of absolute configuration

Organic & biomolecular chemistry, 2006-01, Vol.4 (20), p.3751-3753

2006

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Design, synthesis, and anticancer activity of phosphonic acid diphosphate derivative of adenine-containing butenolide and its water-soluble derivatives of paclitaxel with high antitumor activity

Bioorganic & medicinal chemistry, 2003-10, Vol.11 (20), p.4303-4313

2003

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P3.01-054 Antagonism of a Novel Kinase, MAP3K19, By Specific Small Molecule Inhibitors Blocks Human Primary NSCLC Tumor Growth in Murine Xenograft Models

Journal of thoracic oncology, 2017-01, Vol.12 (1), p.S1152-S1153

2017

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P3.01-054 Antagonism of a Novel Kinase, MAP3K19, By Specific Small Molecule Inhibitors Blocks Human Primary NSCLC Tumor Growth in Murine Xenograft Models: Topic: Models of Lung Cancer

Journal of thoracic oncology, 2017-01, Vol.12 (1), p.S1152-S1153

2017

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Reductive Alkylation of γ-Cyano-α,β-unsaturated Ketones. A Modified Robinson Annulation Process to α,α-Disubstituted β,γ-unsaturated Cyclohexanone System

Synlett, 2001, Vol.2001 (2), p.0214-0217

2001

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Design, Synthesis, and Biological Evaluation of Novel Nucleoside and Nucleotide Analogues as Agents against DNA Viruses and/or Retroviruses

Journal of medicinal chemistry, 2001-10, Vol.44 (22), p.3710-3720

2001

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Design and synthesis of a cephalosporin-retinoic acid prodrug activated by a monoclonal antibody–β-lactamase conjugate

Bioorganic & medicinal chemistry, 2001-08, Vol.9 (8), p.2139-2147

2001

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CRTH2 antagonism significantly ameliorates airway hyperreactivity and downregulates inflammation-induced genes in a mouse model of airway inflammation

American journal of physiology. Lung cellular and molecular physiology, 2008-11, Vol.295 (5), p.L767-L779

2008

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α-Activated Cross Conjugated Cycloalkenone Systems in Organic Synthesis

Current organic synthesis, 2010-02, Vol.7 (1), p.78-93

2010

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Polyene Cyclization Promoted by the Cross-Conjugated α-Carbalkoxy Enone System. Observation on a Putative 1,5-Hydride/1,3-Alkyl Shift under Lewis Acid Catalysis

Organic letters, 2008-01, Vol.10 (1), p.121-123

2008

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A concise total synthesis of (+/-)-acutifolone A

Organic & biomolecular chemistry, 2009-01, Vol.7 (16), p.3285-3290

2009

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Self-Sensitized Photooxygenation of 3,4-Dialkoxyfurans to Vitamin C or Its Derivatives

Journal of organic chemistry, 2001-10, Vol.66 (21), p.7067-7071

2001

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Polyene Cyclization Promoted by the Cross-Conjugated α-Carbalkoxy Cyclohexenone System. An Unusual 1,2-Hydride Shift under Lewis Acid Catalysis

Organic letters, 2009-04, Vol.11 (8), p.1673-1675

2009

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Small-molecule CRTH2 antagonists for the treatment of allergic inflammation: an overview

Expert opinion on investigational drugs, 2005-07, Vol.14 (7), p.769-773

2005

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CRTH2 antagonism significantly ameliorates airway hyperreactivity and downregulates inflammation-induced genes in a mouse model of airway inflammation

American journal of physiology. Lung cellular and molecular physiology, 2008, Vol.39 (5)

2008

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A modified Robinson annulation process to α,α-disubstituted-β,γ-unsaturated cyclohexanone system. Application to the total synthesis of nanaimoal

Tetrahedron, 2003-02, Vol.59 (8), p.1209-1226

2003

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A small molecule CRTH2 antagonist inhibits FITC-induced allergic cutaneous inflammation

A new perspective of cannabinoid 1 receptor antagonists: approaches toward peripheral CB1R blockers without crossing the blood-brain barrier

General Approach to 2,3-Dibenzyl-γ-butyrolactone Lignans: Application to the Total Synthesis of (±)-5′-Methoxyyatein, (±)-5′-Methoxyclusin, and (±)-4′-Hydroxycubebinone

Murine bone marrow-derived mast cells express chemoattractant receptor-homologous molecule expressed on T-helper class 2 cells (CRTh2)

Antagonism of CRTH2 ameliorates chronic epicutaneous sensitization-induced inflammation by multiple mechanisms

MAP3K19 Is a Novel Regulator of TGF-β Signaling That Impacts Bleomycin-Induced Lung Injury and Pulmonary Fibrosis

Targeting MAP3K19 prevents human lung myofibroblast activation both in vitro and in a humanized SCID model of idiopathic pulmonary fibrosis

MAP3K19 Is Overexpressed in COPD and Is a Central Mediator of Cigarette Smoke-Induced Pulmonary Inflammation and Lower Airway Destruction

Application of the Barton photochemical reaction in the synthesis of 1-dethia-3-aza-1-carba-2-oxacephem: a novel agent against resistant pathogenic microorganisms

The first total synthesis of xenitorins B and C: assignment of absolute configuration

Design, synthesis, and anticancer activity of phosphonic acid diphosphate derivative of adenine-containing butenolide and its water-soluble derivatives of paclitaxel with high antitumor activity

P3.01-054 Antagonism of a Novel Kinase, MAP3K19, By Specific Small Molecule Inhibitors Blocks Human Primary NSCLC Tumor Growth in Murine Xenograft Models

P3.01-054 Antagonism of a Novel Kinase, MAP3K19, By Specific Small Molecule Inhibitors Blocks Human Primary NSCLC Tumor Growth in Murine Xenograft Models: Topic: Models of Lung Cancer

Reductive Alkylation of γ-Cyano-α,β-unsaturated Ketones. A Modified Robinson Annulation Process to α,α-Disubstituted β,γ-unsaturated Cyclohexanone System

Design, Synthesis, and Biological Evaluation of Novel Nucleoside and Nucleotide Analogues as Agents against DNA Viruses and/or Retroviruses

Design and synthesis of a cephalosporin-retinoic acid prodrug activated by a monoclonal antibody–β-lactamase conjugate

CRTH2 antagonism significantly ameliorates airway hyperreactivity and downregulates inflammation-induced genes in a mouse model of airway inflammation

α-Activated Cross Conjugated Cycloalkenone Systems in Organic Synthesis

Polyene Cyclization Promoted by the Cross-Conjugated α-Carbalkoxy Enone System. Observation on a Putative 1,5-Hydride/1,3-Alkyl Shift under Lewis Acid Catalysis

A concise total synthesis of (+/-)-acutifolone A

Self-Sensitized Photooxygenation of 3,4-Dialkoxyfurans to Vitamin C or Its Derivatives

Polyene Cyclization Promoted by the Cross-Conjugated α-Carbalkoxy Cyclohexenone System. An Unusual 1,2-Hydride Shift under Lewis Acid Catalysis

Small-molecule CRTH2 antagonists for the treatment of allergic inflammation: an overview

CRTH2 antagonism significantly ameliorates airway hyperreactivity and downregulates inflammation-induced genes in a mouse model of airway inflammation

A modified Robinson annulation process to α,α-disubstituted-β,γ-unsaturated cyclohexanone system. Application to the total synthesis of nanaimoal

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