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Crystal Structure of the Carbohydrate Recognition Domain of the Human Macrophage Galactose C‑Type Lectin Bound to GalNAc and the Tumor-Associated Tn Antigen

Biochemistry (Easton), 2021-05, Vol.60 (17), p.1327-1336

2021

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Structural context of disease-associated mutations and putative mechanism of autoinhibition revealed by X-ray crystallographic analysis of the EZH2-SET domain

PloS one, 2013-12, Vol.8 (12), p.e84147-e84147

2013

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The structural basis for monoclonal antibody 5D2 binding to the tryptophan-rich loop of lipoprotein lipase

Journal of lipid research, 2020-10, Vol.61 (10), p.1347-1359

2020

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Observation of Covalent Intermediates in an Enzyme Mechanism at Atomic Resolution

Science (American Association for the Advancement of Science), 2001-10, Vol.294 (5541), p.369-374

2001

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Structure-based, multi-targeted drug discovery approach to eicosanoid inhibition: Dual inhibitors of mPGES-1 and 5-lipoxygenase activating protein (FLAP)

Biochimica et biophysica acta. General subjects, 2021-02, Vol.1865 (2), p.129800-129800, Article 129800

2021

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Discovery and Characterization of 2‑Acylaminoimidazole Microsomal Prostaglandin E Synthase‑1 Inhibitors

Journal of medicinal chemistry, 2016-01, Vol.59 (1), p.194-205

2016

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Indole Glucocorticoid Receptor Antagonists Active in a Model of Dyslipidemia Act via a Unique Association with an Agonist Binding Site

Journal of medicinal chemistry, 2015-08, Vol.58 (16), p.6607-6618

2015

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2‑Chloro-4-[[(1R,2R)‑2-hydroxy-2-methyl-cyclopentyl]amino]-3-methyl-benzonitrile: A Transdermal Selective Androgen Receptor Modulator (SARM) for Muscle Atrophy

Journal of medicinal chemistry, 2016-01, Vol.59 (2), p.750-755

2016

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Glucocorticoid Receptor Modulators Informed by Crystallography Lead to a New Rationale for Receptor Selectivity, Function, and Implications for Structure-Based Design

Journal of medicinal chemistry, 2014-02, Vol.57 (3), p.849-860

2014

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The 2.5 Å Crystal Structure of the SIRT1 Catalytic Domain Bound to Nicotinamide Adenine Dinucleotide (NAD+) and an Indole (EX527 Analogue) Reveals a Novel Mechanism of Histone Deacetylase Inhibition

Journal of medicinal chemistry, 2013-02, Vol.56 (3), p.963-969

2013

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Discovery and characterization of [(cyclopentyl)ethyl]benzoic acid inhibitors of microsomal prostaglandin E synthase-1

Bioorganic & medicinal chemistry letters, 2017-03, Vol.27 (6), p.1478-1483

2017

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Characterization of 3,3-dimethyl substituted N-aryl piperidines as potent microsomal prostaglandin E synthase-1 inhibitors

Bioorganic & medicinal chemistry letters, 2016-10, Vol.26 (19), p.4824-4828

2016

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Analysis of the Class I Aldolase Binding Site Architecture Based on the Crystal Structure of 2-Deoxyribose-5-phosphate Aldolase at 0.99 Å Resolution

Journal of molecular biology, 2004-10, Vol.343 (4), p.1019-1034

2004

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UM PERNAMBUCO QUE SE QUER EUROPEU: REPRESENTAÇÕES DA CULTURA FRANCESA NO RECIFE OITOCENTISTA E SUAS APLICAÇÕES

Revista rural & urbano : revista científica, 2019-05, Vol.4 (1)

Ferreira da Luz, John Kennedy

2019

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Structures of PHR Domains from Mus musculus Phr1 (Mycbp2) Explain the Loss-of-Function Mutation (Gly1092 → Glu) of the C. elegans Ortholog RPM-1

Journal of molecular biology, 2010-04, Vol.397 (4), p.883-892

2010

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Supine Orientation of a Murine MHC Class I Molecule on the Membrane Bilayer

Current biology, 2004-04, Vol.14 (8), p.718-724

2004

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Crystal structure of viral macrophage inflammatory protein I encoded by Kaposi's sarcoma-associated herpesvirus at 1.7A

Journal of molecular biology, 2005-10, Vol.352 (5), p.1019-1028

2005

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Crystal Structures of mPGES‑1 Inhibitor Complexes Form a Basis for the Rational Design of Potent Analgesic and Anti-Inflammatory Therapeutics

Journal of medicinal chemistry, 2015-06, Vol.58 (11), p.4727-4737

2015

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A Peptide That Antagonizes TCR-Mediated Reactions with Both Syngeneic and Allogeneic Agonists: Functional and Structural Aspects

The Journal of immunology (1950), 2004-03, Vol.172 (5), p.2994-3002

2004

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ENTRE O ENGENHO E A FERROVIA: UMA HISTÓRIA DO CENTRO DO CABO DE SANTO AGOSTINHO, DO SURGIMENTO À CONSOLIDAÇÃO

Revista rural & urbano : revista científica, 2017-09, Vol.2 (2)

2017

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Correction to The 2.5 Å Crystal Structure of the SIRT1 Catalytic Domain Bound to Nicotinamide Adenine Dinucleotide (NAD+) and an Indole (EX527 Analogue) Reveals a Novel Mechanism of Histone Deacetylase Inhibition

Journal of medicinal chemistry, 2016-03, Vol.59 (5), p.2267-2267

2016

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Discovery and characterization of [(cyclopentyl)ethyl]benzoic acid inhibitors of microsomal prostaglandin E synthase-1

Bioorganic & medicinal chemistry letters, 2017-03, Vol.27 (6)

2017

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Discovery and Characterization of 2-Acylaminoimidazole Microsomal Prostaglandin E Synthase-1 Inhibitors

Journal of medicinal chemistry, 2015-12, Vol.59 (1)

2015

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Substrate specificity and kinetic mechanism of the insect sulfotransferase, retinol dehydratase

The Journal of biological chemistry, 1998-12, Vol.273 (52), p.35381-35387

1998

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Characterization of 3,3-dimethyl substituted N-aryl piperidines as potent microsomal prostaglandin E synthase-1 inhibitors

Bioorganic & medicinal chemistry letters, 2016-10, Vol.26 (19)

2016

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Crystal Structure of the Carbohydrate Recognition Domain of the Human Macrophage Galactose C‑Type Lectin Bound to GalNAc and the Tumor-Associated Tn Antigen

Structural context of disease-associated mutations and putative mechanism of autoinhibition revealed by X-ray crystallographic analysis of the EZH2-SET domain

The structural basis for monoclonal antibody 5D2 binding to the tryptophan-rich loop of lipoprotein lipase

Observation of Covalent Intermediates in an Enzyme Mechanism at Atomic Resolution

Structure-based, multi-targeted drug discovery approach to eicosanoid inhibition: Dual inhibitors of mPGES-1 and 5-lipoxygenase activating protein (FLAP)

Discovery and Characterization of 2‑Acylaminoimidazole Microsomal Prostaglandin E Synthase‑1 Inhibitors

Indole Glucocorticoid Receptor Antagonists Active in a Model of Dyslipidemia Act via a Unique Association with an Agonist Binding Site

2‑Chloro-4-[[(1R,2R)‑2-hydroxy-2-methyl-cyclopentyl]amino]-3-methyl-benzonitrile: A Transdermal Selective Androgen Receptor Modulator (SARM) for Muscle Atrophy

Glucocorticoid Receptor Modulators Informed by Crystallography Lead to a New Rationale for Receptor Selectivity, Function, and Implications for Structure-Based Design

The 2.5 Å Crystal Structure of the SIRT1 Catalytic Domain Bound to Nicotinamide Adenine Dinucleotide (NAD+) and an Indole (EX527 Analogue) Reveals a Novel Mechanism of Histone Deacetylase Inhibition

Discovery and characterization of [(cyclopentyl)ethyl]benzoic acid inhibitors of microsomal prostaglandin E synthase-1

Characterization of 3,3-dimethyl substituted N-aryl piperidines as potent microsomal prostaglandin E synthase-1 inhibitors

Analysis of the Class I Aldolase Binding Site Architecture Based on the Crystal Structure of 2-Deoxyribose-5-phosphate Aldolase at 0.99 Å Resolution

UM PERNAMBUCO QUE SE QUER EUROPEU: REPRESENTAÇÕES DA CULTURA FRANCESA NO RECIFE OITOCENTISTA E SUAS APLICAÇÕES

Structures of PHR Domains from Mus musculus Phr1 (Mycbp2) Explain the Loss-of-Function Mutation (Gly1092 → Glu) of the C. elegans Ortholog RPM-1

Supine Orientation of a Murine MHC Class I Molecule on the Membrane Bilayer

Crystal structure of viral macrophage inflammatory protein I encoded by Kaposi's sarcoma-associated herpesvirus at 1.7A

Crystal Structures of mPGES‑1 Inhibitor Complexes Form a Basis for the Rational Design of Potent Analgesic and Anti-Inflammatory Therapeutics

A Peptide That Antagonizes TCR-Mediated Reactions with Both Syngeneic and Allogeneic Agonists: Functional and Structural Aspects

ENTRE O ENGENHO E A FERROVIA: UMA HISTÓRIA DO CENTRO DO CABO DE SANTO AGOSTINHO, DO SURGIMENTO À CONSOLIDAÇÃO

Correction to The 2.5 Å Crystal Structure of the SIRT1 Catalytic Domain Bound to Nicotinamide Adenine Dinucleotide (NAD+) and an Indole (EX527 Analogue) Reveals a Novel Mechanism of Histone Deacetylase Inhibition

Discovery and characterization of [(cyclopentyl)ethyl]benzoic acid inhibitors of microsomal prostaglandin E synthase-1

Discovery and Characterization of 2-Acylaminoimidazole Microsomal Prostaglandin E Synthase-1 Inhibitors

Substrate specificity and kinetic mechanism of the insect sulfotransferase, retinol dehydratase

Characterization of 3,3-dimethyl substituted N-aryl piperidines as potent microsomal prostaglandin E synthase-1 inhibitors

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