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Adapting viral safety assurance strategies to continuous processing of biological products

Biotechnology and bioengineering, 2017-01, Vol.114 (1), p.21-32

2017

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Simple NMR methods for evaluating higher order structures of monoclonal antibody therapeutics with quinary structure

Journal of pharmaceutical and biomedical analysis, 2016-09, Vol.128, p.398-407

2016

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Morphologically-Directed Raman Spectroscopy as an Analytical Method for Subvisible Particle Characterization in Therapeutic Protein Product Quality

Scientific reports, 2023-11, Vol.13 (1), p.20473-20473, Article 20473

2023

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The step-wise framework to design a chromatography-based hydrophobicity assay for viral particles

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2017-09, Vol.1061-1062 (C), p.430-437

2017

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A step‐wise approach to define binding mechanisms of surrogate viral particles to multi‐modal anion exchange resin in a single solute system

Biotechnology and bioengineering, 2017-07, Vol.114 (7), p.1487-1494

2017

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Bioreactor Process Parameter Screening Utilizing a Plackett-Burman Design for a Model Monoclonal Antibody

Journal of pharmaceutical sciences, 2015-06, Vol.104 (6), p.1919-1928

2015

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Adapting viral safety assurance strategies to continuous processing of biological products

Biotechnology and bioengineering, 2017-06, Vol.114 (6), p.1362-1362

2017

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Prediction of N-linked Glycoform Profiles of Monoclonal Antibody with Extracellular Metabolites and Two-Step Intracellular Models

Processes, 2019-04, Vol.7 (4), p.227

2019

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Evaluating the effect of in-process material on the binding mechanisms of surrogate viral particles to a multi-modal anion exchange resin

Journal of biotechnology, 2018-02, Vol.267 (C), p.29-35

2018

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Defining the mechanistic binding of viral particles to a multi‐modal anion exchange resin

Biotechnology progress, 2018-07, Vol.34 (4), p.1019-1026

2018

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Fermentanomics informed amino acid supplementation of an antibody producing mammalian cell culture

Biotechnology progress, 2013-05, Vol.29 (3), p.745-753

2013

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Exploring the linkage between cell culture process parameters and downstream processing utilizing a plackett‐burman design for a model monoclonal antibody

Biotechnology progress, 2017-01, Vol.33 (1), p.163-170

2017

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Proceedings of the 2023 Viral Clearance Symposium, Session 4: Continuous Processing

PDA journal of pharmaceutical science and technology, 2024-03, Vol.78 (2), p.169-175

2024

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Trans‐acting oligodeoxythymidine phosphorothioate triester reagents for transient transfection optimized and facilitated by a high‐throughput microbioreactor system

Biotechnology and applied biochemistry, 2018-05, Vol.65 (3), p.467-475

2018

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Proceedings of the 2019 Viral Clearance Symposium, Session 3: Continuous Processing

PDA journal of pharmaceutical science and technology, 2022-07, Vol.76 (4), p.315-322

2022

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An updated analysis of viral clearance unit operations for biotechnology manufacturing

Current research in biotechnology, 2022, Vol.4, p.190-202

2022

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Analysis of viral clearance unit operations for monoclonal antibodies

Biotechnology and bioengineering, 2010-06, Vol.106 (2), p.238-246

2010

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Characterization of Coliphage PR772 and Evaluation of Its Use for Virus Filter Performance Testing

Applied and Environmental Microbiology, 2004-08, Vol.70 (8), p.4864-4871

2004

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Development of small‐scale models to understand the impact of continuous downstream bioprocessing on integrated virus filtration

Biotechnology progress, 2020-05, Vol.36 (3), p.e2962-n/a

2020

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Hybridoma cell-culture and glycan profile dataset at various bioreactor conditions

Data in brief, 2016-12, Vol.9 (C), p.676-678

2016

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Virus filtration: A review of current and future practices in bioprocessing

Biotechnology and bioengineering, 2022-03, Vol.119 (3), p.743-761

2022

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A design space exploration for control of Critical Quality Attributes of mAb

International journal of pharmaceutics, 2016-10, Vol.512 (1), p.242-252

2016

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Automated 2D-HPLC method for characterization of protein aggregation with in-line fraction collection device

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2017-03, Vol.1046 (C), p.122-130

2017

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Mechanistic failure mode investigation and resolution of parvovirus retentive filters

Biotechnology progress, 2016-07, Vol.32 (4), p.959-970

2016

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Validation and optimization of viral clearance in a downstream continuous chromatography setting

Biotechnology and bioengineering, 2019-09, Vol.116 (9), p.2292-2302

2019

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Adapting viral safety assurance strategies to continuous processing of biological products

Simple NMR methods for evaluating higher order structures of monoclonal antibody therapeutics with quinary structure

Morphologically-Directed Raman Spectroscopy as an Analytical Method for Subvisible Particle Characterization in Therapeutic Protein Product Quality

The step-wise framework to design a chromatography-based hydrophobicity assay for viral particles

A step‐wise approach to define binding mechanisms of surrogate viral particles to multi‐modal anion exchange resin in a single solute system

Bioreactor Process Parameter Screening Utilizing a Plackett-Burman Design for a Model Monoclonal Antibody

Adapting viral safety assurance strategies to continuous processing of biological products

Prediction of N-linked Glycoform Profiles of Monoclonal Antibody with Extracellular Metabolites and Two-Step Intracellular Models

Evaluating the effect of in-process material on the binding mechanisms of surrogate viral particles to a multi-modal anion exchange resin

Defining the mechanistic binding of viral particles to a multi‐modal anion exchange resin

Fermentanomics informed amino acid supplementation of an antibody producing mammalian cell culture

Exploring the linkage between cell culture process parameters and downstream processing utilizing a plackett‐burman design for a model monoclonal antibody

Proceedings of the 2023 Viral Clearance Symposium, Session 4: Continuous Processing

Trans‐acting oligodeoxythymidine phosphorothioate triester reagents for transient transfection optimized and facilitated by a high‐throughput microbioreactor system

Proceedings of the 2019 Viral Clearance Symposium, Session 3: Continuous Processing

An updated analysis of viral clearance unit operations for biotechnology manufacturing

Analysis of viral clearance unit operations for monoclonal antibodies

Characterization of Coliphage PR772 and Evaluation of Its Use for Virus Filter Performance Testing

Development of small‐scale models to understand the impact of continuous downstream bioprocessing on integrated virus filtration

Hybridoma cell-culture and glycan profile dataset at various bioreactor conditions

Virus filtration: A review of current and future practices in bioprocessing

A design space exploration for control of Critical Quality Attributes of mAb

Automated 2D-HPLC method for characterization of protein aggregation with in-line fraction collection device

Mechanistic failure mode investigation and resolution of parvovirus retentive filters

Validation and optimization of viral clearance in a downstream continuous chromatography setting

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