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Good manufacturing practice production of adenoviral vectors for clinical trials

Human gene therapy, 2005-03, Vol.16 (3), p.281-291

LUSKY, Monika

2005

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PHOCUS: A Phase 3, Randomized, Open-Label Study of Sequential Treatment with Pexa-Vec (JX-594) and Sorafenib in Patients with Advanced Hepatocellular Carcinoma

Liver cancer (Basel ), 2024-06, Vol.13 (3), p.256-272

2024

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TG1042 (Adenovirus-interferon-γ) in primary cutaneous B-cell lymphomas: a phase II clinical trial

PloS one, 2014-02, Vol.9 (2), p.e83670-e83670

2014

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Modulation of the inflammatory properties and hepatotoxicity of recombinant adenovirus vectors by the viral E4 gene products

Human gene therapy, 2000-02, Vol.11 (3), p.415-427

2000

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Neoadjuvant Intravenous Oncolytic Vaccinia Virus Therapy Promotes Anticancer Immunity in Patients

Cancer immunology research, 2022-06, Vol.10 (6), p.745-756

2022

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Immunogenicity of oncolytic vaccinia viruses JX-GFP and TG6002 in a human melanoma in vitro model: studying immunogenic cell death, dendritic cell maturation and interaction with cytotoxic T lymphocytes

OncoTargets and therapy, 2017-01, Vol.10, p.2389-2401

2017

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Vaccinia Virus Shuffling: deVV5, a Novel Chimeric Poxvirus with Improved Oncolytic Potency

Cancers, 2018-07, Vol.10 (7), p.231

2018

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Intravenous Oncolytic Vaccinia Virus Therapy Results in a Differential Immune Response between Cancer Patients

Cancers, 2022-04, Vol.14 (9), p.2181

2022

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Inhibition of SV40 replication in simian cells by specific pBR322 DNA sequences

Nature (London), 1981-09, Vol.293 (5827), p.79-81

1981

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PHOCUS: A phase 3 randomized, open-label study comparing the oncolytic immunotherapy Pexa-Vec followed by sorafenib (SOR) vs SOR in patients with advanced hepatocellular carcinoma (HCC) without prior systemic therapy

Journal of clinical oncology, 2016-05, Vol.34 (15_suppl), p.TPS4146-TPS4146

2016

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Phase II Clinical Trial of Intratumoral Application of TG1042 (Adenovirus-interferon-γ) in Patients With Advanced Cutaneous T-cell Lymphomas and Multilesional Cutaneous B-cell Lymphomas

Molecular therapy, 2010-06, Vol.18 (6), p.1244-1247

2010

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Targeted Chemotherapy for Head and Neck Cancer with a Chimeric Oncolytic Adenovirus Coding for Bifunctional Suicide Protein FCU1

Clinical cancer research, 2010-05, Vol.16 (9), p.2540-2549

2010

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TG1042

PloS one, 2014-02, Vol.9 (2), p.e83670

2014

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Oncolytic vaccinia virus: a silver bullet?

Expert review of vaccines, 2010-12, Vol.9 (12), p.1353-1356

2010

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Phase IIb randomized trial of JX-594, a targeted multimechanistic oncolytic vaccinia virus, plus best supportive care (BSC) versus BSC alone in patients with advanced hepatocellular carcinoma who have failed sorafenib treatment (TRAVERSE)

Journal of clinical oncology, 2012-05, Vol.30 (15_suppl), p.TPS4152-TPS4152

2012

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Phase IIb randomized trial of Pexa-Vec (pexastimogene devacirepvec; JX-594), a targeted oncolytic vaccinia virus, plus best supportive care (BSC) versus BSC alone in patients with advanced hepatocellular carcinoma who have failed sorafenib treatment (TRAVERSE)

Journal of clinical oncology, 2013-05, Vol.31 (15_suppl), p.TPS4161-TPS4161

2013

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Cellular Localization and Activity of Ad-Delivered GFP-CFTR in Airway Epithelial and Tracheal Cells

American journal of respiratory cell and molecular biology, 2007-12, Vol.37 (6), p.631-639

2007

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Identification of the Glycosylation Site of the Adenovirus Type 5 Fiber Protein

Biochemistry (Easton), 2005-04, Vol.44 (14), p.5453-5460

2005

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TG1042 (Adenovirus-interferon- gamma ) in Primary Cutaneous B-cell Lymphomas: A Phase II Clinical Trial: e83670

PloS one, 2014-02, Vol.9 (2)

2014

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Bovine papilloma virus (BPV)-encoded E1 protein contains multiple activities required for BPV DNA replication

Proceedings of the National Academy of Sciences - PNAS, 1993-01, Vol.90 (2), p.702-706

1993

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Gene therapy with recombinant adenovirus vectors: evaluation of the host immune response

Immunology letters, 1997-06, Vol.57 (1), p.19-25

1997

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Bovine Papilloma Virus (BPV)-Encoded E2 Protein Enhances Binding of E1 Protein to the BPV Replication Origin

Proceedings of the National Academy of Sciences - PNAS, 1993-04, Vol.90 (7), p.2865-2869

1993

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119. Studies on the Targeting of Adenoviral Vectors Carrying a Tumor-Cell Specific Peptide

Molecular therapy, 2004-05, Vol.9 (S1), p.S46-S46

2004

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Transductional targeting with recombinant adenovirus vectors

Current gene therapy, 2002-09, Vol.2 (3), p.323-339

2002

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The bovine papillomavirus E2 protein modulates the assembly of but is not stably maintained in a replication-competent multimeric E1-replication origin complex

Proceedings of the National Academy of Sciences - PNAS, 1994-09, Vol.91 (19), p.8895-8899

1994

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Good manufacturing practice production of adenoviral vectors for clinical trials

PHOCUS: A Phase 3, Randomized, Open-Label Study of Sequential Treatment with Pexa-Vec (JX-594) and Sorafenib in Patients with Advanced Hepatocellular Carcinoma

TG1042 (Adenovirus-interferon-γ) in primary cutaneous B-cell lymphomas: a phase II clinical trial

Modulation of the inflammatory properties and hepatotoxicity of recombinant adenovirus vectors by the viral E4 gene products

Neoadjuvant Intravenous Oncolytic Vaccinia Virus Therapy Promotes Anticancer Immunity in Patients

Immunogenicity of oncolytic vaccinia viruses JX-GFP and TG6002 in a human melanoma in vitro model: studying immunogenic cell death, dendritic cell maturation and interaction with cytotoxic T lymphocytes

Vaccinia Virus Shuffling: deVV5, a Novel Chimeric Poxvirus with Improved Oncolytic Potency

Intravenous Oncolytic Vaccinia Virus Therapy Results in a Differential Immune Response between Cancer Patients

Inhibition of SV40 replication in simian cells by specific pBR322 DNA sequences

PHOCUS: A phase 3 randomized, open-label study comparing the oncolytic immunotherapy Pexa-Vec followed by sorafenib (SOR) vs SOR in patients with advanced hepatocellular carcinoma (HCC) without prior systemic therapy

Phase II Clinical Trial of Intratumoral Application of TG1042 (Adenovirus-interferon-γ) in Patients With Advanced Cutaneous T-cell Lymphomas and Multilesional Cutaneous B-cell Lymphomas

Targeted Chemotherapy for Head and Neck Cancer with a Chimeric Oncolytic Adenovirus Coding for Bifunctional Suicide Protein FCU1

TG1042

Oncolytic vaccinia virus: a silver bullet?

Phase IIb randomized trial of JX-594, a targeted multimechanistic oncolytic vaccinia virus, plus best supportive care (BSC) versus BSC alone in patients with advanced hepatocellular carcinoma who have failed sorafenib treatment (TRAVERSE)

Phase IIb randomized trial of Pexa-Vec (pexastimogene devacirepvec; JX-594), a targeted oncolytic vaccinia virus, plus best supportive care (BSC) versus BSC alone in patients with advanced hepatocellular carcinoma who have failed sorafenib treatment (TRAVERSE)

Cellular Localization and Activity of Ad-Delivered GFP-CFTR in Airway Epithelial and Tracheal Cells

Identification of the Glycosylation Site of the Adenovirus Type 5 Fiber Protein

TG1042 (Adenovirus-interferon- gamma ) in Primary Cutaneous B-cell Lymphomas: A Phase II Clinical Trial: e83670

Bovine papilloma virus (BPV)-encoded E1 protein contains multiple activities required for BPV DNA replication

Gene therapy with recombinant adenovirus vectors: evaluation of the host immune response

Bovine Papilloma Virus (BPV)-Encoded E2 Protein Enhances Binding of E1 Protein to the BPV Replication Origin

119. Studies on the Targeting of Adenoviral Vectors Carrying a Tumor-Cell Specific Peptide

Transductional targeting with recombinant adenovirus vectors

The bovine papillomavirus E2 protein modulates the assembly of but is not stably maintained in a replication-competent multimeric E1-replication origin complex

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