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Crystal Structure of Human DNA Methyltransferase 1

Journal of molecular biology, 2015-07, Vol.427 (15), p.2520-2531

2015

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Design, synthesis, and antibacterial evaluation of novel derivatives of NPS-2143 for the treatment of methicillin-resistant S. aureus (MRSA) infection

Journal of antibiotics, 2019-07, Vol.72 (7), p.545-554

2019

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Design, synthesis and evaluation of scutellarein-O-alkylamines as multifunctional agents for the treatment of Alzheimer's disease

European journal of medicinal chemistry, 2015-04, Vol.94, p.348-366

2015

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Biophysical and biochemical properties of PHGDH revealed by studies on PHGDH inhibitors

Cellular and molecular life sciences : CMLS, 2022, Vol.79 (1), p.27, Article 27

2022

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Mycobacterium tuberculosis : Pathogenesis and therapeutic targets

MedComm (2020), 2023-10, Vol.4 (5), p.e353-n/a

2023

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Pseudomonas aeruginosa regulator PvrA binds simultaneously to multiple pseudo-palindromic sites for efficient transcription activation

Science China. Life sciences, 2024-05, Vol.67 (5), p.900-912

2024

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Design and synthesis of novel spirooxindole–indenoquinoxaline derivatives as novel tryptophanyl-tRNA synthetase inhibitors

Molecular diversity, 2020-11, Vol.24 (4), p.1043-1063

2020

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Structure–activity relationship study of DEL-22379: ERK dimerization inhibitors with increased safety

Molecular diversity, 2021-05, Vol.25 (2), p.1051-1075

2021

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A Novel Small Molecule, LCG-N25, Inhibits Oral Streptococcal Biofilm

Frontiers in microbiology, 2021-03, Vol.12, p.654692-654692

2021

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Discovery of hybrids of indolin-2-one and nitroimidazole as potent inhibitors against drug-resistant bacteria

Journal of antibiotics, 2018-10, Vol.71 (10), p.887-897

2018

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Targeting human caseinolytic protease P (ClpP) as a novel therapeutic strategy in ovarian cancer

MedComm - Oncology, 2022-06, Vol.1 (1), p.n/a

2022

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Synthesis of N-Substituted Benzamide Derivatives and their Evaluation as Antitumor Agents

Medicinal chemistry (Shp-sariqah, United Arab Emirates), 2020-01, Vol.16 (4), p.555-562

2020

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Synthesis and biological evaluation of innovative thiourea derivatives as PHGDH inhibitors

Chemical papers, 2020-11, Vol.74 (11), p.3873-3886

2020

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Design, synthesis and biological evaluation of novel pyrrole derivatives as potential ClpP1P2 inhibitor against Mycobacterium tuberculosis

Bioorganic chemistry, 2018-10, Vol.80, p.422-432

2018

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Antimicrobial activities of a small molecule compound II-6s against oral streptococci

Journal of oral microbiology, 2021-01, Vol.13 (1), p.1909917-1909917

2021

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Study on Typical Diarylurea Drugs or Derivatives in Cocrystallizing with Strong H‑Bond Acceptor DMSO

ACS omega, 2021-03, Vol.6 (8), p.5532-5547

2021

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A novel series of human dihydroorotate dehydrogenase inhibitors discovered by in vitro screening: inhibition activity and crystallographic binding mode

FEBS open bio, 2019-08, Vol.9 (8), p.1348-1354

2019

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A small molecule II-6s inhibits Enterococcus faecalis biofilms

Journal of oral microbiology, 2021-01, Vol.13 (1), p.1978756-1978756

2021

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Mitochondrial quality control proteases and their modulation for cancer therapy

Medicinal research reviews, 2023-03, Vol.43 (2), p.399-436

2023

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A novel and potent dihydroorotate dehydrogenase inhibitor suppresses the proliferation of colorectal cancer by inducing mitochondrial dysfunction and DNA damage

MedComm - Oncology, 2022-06, Vol.1 (1), p.n/a

2022

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Discovery of (Z)-5-(4-Methoxybenzylidene)thiazolidine-2,4-dione, a Readily Available and Orally Active Glitazone for the Treatment of Concanavalin A-Induced Acute Liver Injury of BALB/c Mice

Journal of medicinal chemistry, 2010-01, Vol.53 (1), p.273-281

2010

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Preparative isolation and purification of three rotenoids and one isoflavone from the seeds of Millettia pachycarpa Benth by high-speed counter-current chromatography

Journal of Chromatography A, 2008-01, Vol.1178 (1), p.101-107

2008

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Application of covalent modality in proximity-induced drug pharmacology: Early development, current strategy, and feature directions

European journal of medicinal chemistry, 2024-05, Vol.271, p.116394-116394, Article 116394

2024

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Dihydrofolate reductase inhibitors for use as antimicrobial agents

European journal of medicinal chemistry, 2020-06, Vol.195, p.112268-112268, Article 112268

2020

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STATs, promising targets for the treatment of autoimmune and inflammatory diseases

European journal of medicinal chemistry, 2024-11, Vol.277, p.116783, Article 116783

2024

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Crystal Structure of Human DNA Methyltransferase 1

Design, synthesis, and antibacterial evaluation of novel derivatives of NPS-2143 for the treatment of methicillin-resistant S. aureus (MRSA) infection

Design, synthesis and evaluation of scutellarein-O-alkylamines as multifunctional agents for the treatment of Alzheimer's disease

Biophysical and biochemical properties of PHGDH revealed by studies on PHGDH inhibitors

Mycobacterium tuberculosis : Pathogenesis and therapeutic targets

Pseudomonas aeruginosa regulator PvrA binds simultaneously to multiple pseudo-palindromic sites for efficient transcription activation

Design and synthesis of novel spirooxindole–indenoquinoxaline derivatives as novel tryptophanyl-tRNA synthetase inhibitors

Structure–activity relationship study of DEL-22379: ERK dimerization inhibitors with increased safety

A Novel Small Molecule, LCG-N25, Inhibits Oral Streptococcal Biofilm

Discovery of hybrids of indolin-2-one and nitroimidazole as potent inhibitors against drug-resistant bacteria

Targeting human caseinolytic protease P (ClpP) as a novel therapeutic strategy in ovarian cancer

Synthesis of N-Substituted Benzamide Derivatives and their Evaluation as Antitumor Agents

Synthesis and biological evaluation of innovative thiourea derivatives as PHGDH inhibitors

Design, synthesis and biological evaluation of novel pyrrole derivatives as potential ClpP1P2 inhibitor against Mycobacterium tuberculosis

Antimicrobial activities of a small molecule compound II-6s against oral streptococci

Study on Typical Diarylurea Drugs or Derivatives in Cocrystallizing with Strong H‑Bond Acceptor DMSO

A novel series of human dihydroorotate dehydrogenase inhibitors discovered by in vitro screening: inhibition activity and crystallographic binding mode

A small molecule II-6s inhibits Enterococcus faecalis biofilms

Mitochondrial quality control proteases and their modulation for cancer therapy

A novel and potent dihydroorotate dehydrogenase inhibitor suppresses the proliferation of colorectal cancer by inducing mitochondrial dysfunction and DNA damage

Discovery of (Z)-5-(4-Methoxybenzylidene)thiazolidine-2,4-dione, a Readily Available and Orally Active Glitazone for the Treatment of Concanavalin A-Induced Acute Liver Injury of BALB/c Mice

Preparative isolation and purification of three rotenoids and one isoflavone from the seeds of Millettia pachycarpa Benth by high-speed counter-current chromatography

Application of covalent modality in proximity-induced drug pharmacology: Early development, current strategy, and feature directions

Dihydrofolate reductase inhibitors for use as antimicrobial agents

STATs, promising targets for the treatment of autoimmune and inflammatory diseases

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