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Late-Stage Diversification of Natural Products

ACS central science, 2020-05, Vol.6 (5), p.622-635

2020

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Elimination of senescent cells by β-galactosidase-targeted prodrug attenuates inflammation and restores physical function in aged mice

Cell research, 2020-07, Vol.30 (7), p.574-589

2020

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Strategic innovation in the total synthesis of complex natural products using gold catalysis

Natural product reports, 2014-01, Vol.31 (4), p.489-53

2014

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Enantioselective Total Synthesis of (+)-Wortmannin

Journal of the American Chemical Society, 2017-05, Vol.139 (20), p.6815-6818

2017

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Structural insights into the inhibition mechanism of human sterol O-acyltransferase 1 by a competitive inhibitor

Nature communications, 2020-05, Vol.11 (1), p.2478-2478, Article 2478

2020

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Total Synthesis of (−)-Oridonin: An Interrupted Nazarov Approach

Journal of the American Chemical Society, 2019-12, Vol.141 (51), p.20048-20052

2019

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Chemoproteomics reveals baicalin activates hepatic CPT1 to ameliorate diet-induced obesity and hepatic steatosis

Proceedings of the National Academy of Sciences - PNAS, 2018-06, Vol.115 (26), p.E5896-E5905

2018

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Total Syntheses of (−)-Hibiscone C and Lysergine: A Cyclization/Fragmentation Strategy

Organic letters, 2017-02, Vol.19 (3), p.620-623

2017

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Divergent syntheses of complex Veratrum alkaloids

Nature communications, 2024-09, Vol.15 (1), p.7639-7, Article 7639

2024

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Total Synthesis of Maoecrystal P: Application of a Strained Bicyclic Synthon

Angewandte Chemie International Edition, 2018-01, Vol.57 (3), p.760-764

International ed. in English, 2018

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Enantioselective synthesis of Iboga alkaloids and vinblastine via rearrangements of quaternary ammoniums

Chemical science (Cambridge), 2016-01, Vol.7 (8), p.5530-5536

2016

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Total Synthesis of (−)-Batrachotoxinin A: A Local-Desymmetrization Approach

Journal of the American Chemical Society, 2020-02, Vol.142 (8), p.3675-3679

2020

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Gold(I)-Catalyzed Coupling Reactions for the Synthesis of Diverse Small Molecules Using the Build/Couple/Pair Strategy

Journal of the American Chemical Society, 2009-04, Vol.131 (15), p.5667-5674

2009

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Total Syntheses of Drimane-Type Sesquiterpenoids Enabled by a Gold-Catalyzed Tandem Reaction

Journal of the American Chemical Society, 2011-09, Vol.133 (38), p.14944-14947

2011

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Collective Synthesis of Cladiellins Based on the Gold-Catalyzed Cascade Reaction of 1,7-Diynes

Angewandte Chemie International Edition, 2014-02, Vol.53 (7), p.1837-1840

International ed. in English, 2014

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Synthetic Progress toward Azadirachtins. 1. Enantio- and Diastereoselective Synthesis of the Left-Wing Fragment of 11-epi-Azadirachtin I

Organic letters, 2015-05, Vol.17 (10), p.2342-2345

2015

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Synthetic Progress toward Azadirachtins. 2. Enantio- and Diastereoselective Synthesis of the Right-Wing Fragment of 11-epi-Azadirachtin I

Organic letters, 2015-05, Vol.17 (10), p.2338-2341

2015

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Effective treatment of SARS-CoV-2-infected rhesus macaques by attenuating inflammation

Cell research, 2021-02, Vol.31 (2), p.229-232

2021

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Discovery of histone deacetylase 8 selective inhibitors

Bioorganic & medicinal chemistry letters, 2011-05, Vol.21 (9), p.2601-2605

2011

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Simple β-lactones are potent irreversible antagonists for strigolactone receptors

Cell research, 2017-12, Vol.27 (12), p.1525-1528

2017

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A small-molecule approach towards the Fountain of Youth: chemically induced pluripotent stem cells

National science review, 2022-11, Vol.9 (11), p.nwac181-nwac181

Luo, Tuoping

2022

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Gold-Catalyzed Enantio- and Diastereoselective Syntheses of Left Fragments of Azadirachtin/Meliacarpin-Type Limonoids

Journal of organic chemistry, 2016-02, Vol.81 (3), p.751-771

2016

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STK33 kinase inhibitor BRD-8899 has no effect on KRAS-dependent cancer cell viability

Proceedings of the National Academy of Sciences - PNAS, 2012-02, Vol.109 (8), p.2860-2865

2012

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Enantioselective Biomimetic Total Syntheses of Katsumadain and Katsumadain C

Organic letters, 2012-01, Vol.14 (1), p.162-165

2012

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Gold-catalyzed cyclization and cycloaddition in natural product synthesis

Natural product reports, 2024-07, Vol.41 (7), p.191-1112

2024

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Late-Stage Diversification of Natural Products

Elimination of senescent cells by β-galactosidase-targeted prodrug attenuates inflammation and restores physical function in aged mice

Strategic innovation in the total synthesis of complex natural products using gold catalysis

Enantioselective Total Synthesis of (+)-Wortmannin

Structural insights into the inhibition mechanism of human sterol O-acyltransferase 1 by a competitive inhibitor

Total Synthesis of (−)-Oridonin: An Interrupted Nazarov Approach

Chemoproteomics reveals baicalin activates hepatic CPT1 to ameliorate diet-induced obesity and hepatic steatosis

Total Syntheses of (−)-Hibiscone C and Lysergine: A Cyclization/Fragmentation Strategy

Divergent syntheses of complex Veratrum alkaloids

Total Synthesis of Maoecrystal P: Application of a Strained Bicyclic Synthon

Enantioselective synthesis of Iboga alkaloids and vinblastine via rearrangements of quaternary ammoniums

Total Synthesis of (−)-Batrachotoxinin A: A Local-Desymmetrization Approach

Gold(I)-Catalyzed Coupling Reactions for the Synthesis of Diverse Small Molecules Using the Build/Couple/Pair Strategy

Total Syntheses of Drimane-Type Sesquiterpenoids Enabled by a Gold-Catalyzed Tandem Reaction

Collective Synthesis of Cladiellins Based on the Gold-Catalyzed Cascade Reaction of 1,7-Diynes

Synthetic Progress toward Azadirachtins. 1. Enantio- and Diastereoselective Synthesis of the Left-Wing Fragment of 11-epi-Azadirachtin I

Synthetic Progress toward Azadirachtins. 2. Enantio- and Diastereoselective Synthesis of the Right-Wing Fragment of 11-epi-Azadirachtin I

Effective treatment of SARS-CoV-2-infected rhesus macaques by attenuating inflammation

Discovery of histone deacetylase 8 selective inhibitors

Simple β-lactones are potent irreversible antagonists for strigolactone receptors

A small-molecule approach towards the Fountain of Youth: chemically induced pluripotent stem cells

Gold-Catalyzed Enantio- and Diastereoselective Syntheses of Left Fragments of Azadirachtin/Meliacarpin-Type Limonoids

STK33 kinase inhibitor BRD-8899 has no effect on KRAS-dependent cancer cell viability

Enantioselective Biomimetic Total Syntheses of Katsumadain and Katsumadain C

Gold-catalyzed cyclization and cycloaddition in natural product synthesis

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