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Degradation of lipid droplets by chimeric autophagy-tethering compounds

Cell research, 2021-09, Vol.31 (9), p.965-979

2021

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Allele-selective lowering of mutant HTT protein by HTT-LC3 linker compounds

Nature (London), 2019-11, Vol.575 (7781), p.203-209

2019

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BCL2L11/BIM: A novel molecular link between autophagy and apoptosis

Autophagy, 2013-01, Vol.9 (1), p.104-105

2013

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Accumulation of autophagosomes confers cytotoxicity

The Journal of biological chemistry, 2017-08, Vol.292 (33), p.13599-13614

2017

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Blood biomarker-based classification study for neurodegenerative diseases

Scientific reports, 2023-10, Vol.13 (1), p.17191-17191, Article 17191

2023

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Lowering Mutant Huntingtin Levels and Toxicity: Autophagy-Endolysosome Pathways in Huntington's Disease

Journal of molecular biology, 2020-04, Vol.432 (8), p.2673-2691

2020

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Regulation of mammalian autophagy in physiology and pathophysiology

Physiological reviews, 2010-10, Vol.90 (4), p.1383-1435

2010

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Cytoplasmic DAXX drives SQSTM1/p62 phase condensation to activate Nrf2-mediated stress response

Nature communications, 2019-08, Vol.10 (1), p.3759-18, Article 3759

2019

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Complex Inhibitory Effects of Nitric Oxide on Autophagy

Molecular cell, 2011-07, Vol.43 (1), p.19-32

2011

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The BEACH-containing protein WDR81 coordinates p62 and LC3C to promote aggrephagy

The Journal of cell biology, 2017-05, Vol.216 (5), p.1301-1320

2017

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Exosome release and neuropathology induced by α-synuclein: new insights into protective mechanisms of Drp1 inhibition

Acta neuropathologica communications, 2019-11, Vol.7 (1), p.184-18, Article 184

2019

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Prominin‐1 controls stem cell activation by orchestrating ciliary dynamics

The EMBO journal, 2019-01, Vol.38 (2), p.n/a

2019

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Autophagic activity in neuronal cell death

Neuroscience bulletin, 2015-08, Vol.31 (4), p.382-394

2015

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Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease

Nature genetics, 2004-06, Vol.36 (6), p.585-595

2004

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Discovery of SQSTM1/p62-dependent P-bodies that regulate the NLRP3 inflammasome

Cell reports (Cambridge), 2024-03, Vol.43 (3), p.113935-113935, Article 113935

2024

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A partial Drp1 knockout improves autophagy flux independent of mitochondrial function

Molecular neurodegeneration, 2024-03, Vol.19 (1), p.26-26, Article 26

2024

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Dual PI-3 kinase/mTOR inhibition impairs autophagy flux and induces cell death independent of apoptosis and necroptosis

Oncotarget, 2016-02, Vol.7 (5), p.5157-5175

2016

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Caspase-mediated cleavage of C53/LZAP protein causes abnormal microtubule bundling and rupture of the nuclear envelope

Cell research, 2013-05, Vol.23 (5), p.691-704

2013

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p21-activated kinase 1 promotes soluble mutant huntingtin self-interaction and enhances toxicity

Human molecular genetics, 2008-03, Vol.17 (6), p.895-905

2008

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Cdk5 Activator-binding Protein C53 Regulates Apoptosis Induced by Genotoxic Stress via Modulating the G2/M DNA Damage Checkpoint

The Journal of biological chemistry, 2005-05, Vol.280 (21), p.20651-20659

2005

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Ubiquitin ligase Hrd1 enhances the degradation and suppresses the toxicity of polyglutamine-expanded huntingtin

Experimental cell research, 2007-02, Vol.313 (3), p.538-550

2007

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Mitochondrial integrity in neurodegeneration

CNS neuroscience & therapeutics, 2019-07, Vol.25 (7), p.825-836

2019

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Conformation Polymorphism of Polyglutamine Proteins

Trends in biochemical sciences (Amsterdam. Regular ed.), 2018-06, Vol.43 (6), p.424-435

2018

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Cytoprotective roles for autophagy

Current opinion in cell biology, 2010-04, Vol.22 (2), p.206-211

2010

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α Pix enhances mutant huntingtin aggregation

Journal of the neurological sciences, 2010-03, Vol.290 (1), p.80-85

2010

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Degradation of lipid droplets by chimeric autophagy-tethering compounds

Allele-selective lowering of mutant HTT protein by HTT-LC3 linker compounds

BCL2L11/BIM: A novel molecular link between autophagy and apoptosis

Accumulation of autophagosomes confers cytotoxicity

Blood biomarker-based classification study for neurodegenerative diseases

Lowering Mutant Huntingtin Levels and Toxicity: Autophagy-Endolysosome Pathways in Huntington's Disease

Regulation of mammalian autophagy in physiology and pathophysiology

Cytoplasmic DAXX drives SQSTM1/p62 phase condensation to activate Nrf2-mediated stress response

Complex Inhibitory Effects of Nitric Oxide on Autophagy

The BEACH-containing protein WDR81 coordinates p62 and LC3C to promote aggrephagy

Exosome release and neuropathology induced by α-synuclein: new insights into protective mechanisms of Drp1 inhibition

Prominin‐1 controls stem cell activation by orchestrating ciliary dynamics

Autophagic activity in neuronal cell death

Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease

Discovery of SQSTM1/p62-dependent P-bodies that regulate the NLRP3 inflammasome

A partial Drp1 knockout improves autophagy flux independent of mitochondrial function

Dual PI-3 kinase/mTOR inhibition impairs autophagy flux and induces cell death independent of apoptosis and necroptosis

Caspase-mediated cleavage of C53/LZAP protein causes abnormal microtubule bundling and rupture of the nuclear envelope

p21-activated kinase 1 promotes soluble mutant huntingtin self-interaction and enhances toxicity

Cdk5 Activator-binding Protein C53 Regulates Apoptosis Induced by Genotoxic Stress via Modulating the G2/M DNA Damage Checkpoint

Ubiquitin ligase Hrd1 enhances the degradation and suppresses the toxicity of polyglutamine-expanded huntingtin

Mitochondrial integrity in neurodegeneration

Conformation Polymorphism of Polyglutamine Proteins

Cytoprotective roles for autophagy

α Pix enhances mutant huntingtin aggregation

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