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A state-of-the-art review and feasibility analysis of high altitude wind power in Northern Ireland

Renewable & sustainable energy reviews, 2017-02, Vol.68, p.899-911

2017

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4-Hydroxy-5,6-dihydropyrones as Inhibitors of HIV Protease: The Effect of Heterocyclic Substituents at C-6 on Antiviral Potency and Pharmacokinetic Parameters

Journal of medicinal chemistry, 2001-07, Vol.44 (14), p.2319-2332

2001

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An Alpha-Mercaptoacrylic Acid Derivative is a Selective Nonpeptide Cell-Permeable Calpain Inhibitor and is Neuroprotective

Proceedings of the National Academy of Sciences - PNAS, 1996-06, Vol.93 (13), p.6687-6692

1996

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Design, Synthesis, and Cocrystal Structure of a Nonpeptide Src SH2 Domain Ligand

Journal of medicinal chemistry, 1997-11, Vol.40 (23), p.3719-3725

1997

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4-Hydroxy-5,6-dihydropyrones. 2. Potent Non-Peptide Inhibitors of HIV Protease

Journal of medicinal chemistry, 1997-11, Vol.40 (23), p.3781-3792

1997

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5,6-Dihydropyran-2-ones Possessing Various Sulfonyl Functionalities: Potent Nonpeptidic Inhibitors of HIV Protease

Journal of medicinal chemistry, 2000-03, Vol.43 (5), p.843-858

2000

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A Novel Nonpeptide HIV-1 Protease Inhibitor: Elucidation of the Binding Mode and Its Application in the Design of Related Analogs

Journal of medicinal chemistry, 1994-08, Vol.37 (17), p.2664-2677

1994

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Synthesis of 5,6-Dihydro-4-hydroxy-2- pyrones as HIV-1 Protease Inhibitors: The Profound Effect of Polarity on Antiviral Activity

Journal of medicinal chemistry, 1997-11, Vol.40 (23), p.3707-3711

1997

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Statistical elements of predicting the impact of a variety of odour sources

Water science and technology, 2001-01, Vol.44 (9), p.157-164

2001

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Novel Series of Achiral, Low Molecular Weight, and Potent HIV-1 Protease Inhibitors

Journal of the American Chemical Society, 1994-07, Vol.116 (15), p.6989-6990

1994

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Analysis of the Binding of Hydroxamic Acid and Carboxylic Acid Inhibitors to the Stromelysin-1 (Matrix Metalloproteinase-3) Catalytic Domain by Isothermal Titration Calorimetry

Biochemistry (Easton), 1999-10, Vol.38 (41), p.13592-13601

1999

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Renin inhibitors containing isosteric replacements of the amide bond connecting the P3 and P2 sites

Journal of medicinal chemistry, 1990-02, Vol.33 (2), p.838-845

1990

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Computing in drug discovery: the design phase

Computing in science & engineering, 2001-09, Vol.3 (5), p.105-108

Lunney, E.A.

2001

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Memories of metallothionein

Biochimica et Biophysica Acta (BBA)/Protein Structure and Molecular Enzymology, 1994-04, Vol.1205 (2), p.151-161

1994

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Nonpeptidic HIV protease inhibitors possessing excellent antiviral activities and therapeutic indices. PD 178390 : A lead HIV protease inhibitor

Bioorganic & medicinal chemistry, 1999-12, Vol.7 (12), p.2775-2800

1999

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Structure-based design of caspase-1 inhibitor containing a diphenyl ether sulfonamide

Bioorganic & medicinal chemistry letters, 2001-10, Vol.11 (20), p.2779-2782

2001

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Nonpeptidic HIV protease inhibitors: 6-alkyl-5,6-dihydropyran-2-ones possessing a novel and achiral 3-(2- t-butyl-5-methyl-4-sulfamate)phenylthio moiety

Bioorganic & medicinal chemistry letters, 1999-08, Vol.9 (15), p.2217-2222

1999

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X-ray crystallographic analysis of inhibition of endothiapepsin by cyclohexyl renin inhibitors

Biochemistry (Easton), 1992-09, Vol.31 (35), p.8142-8150

1992

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Stereoselective binding of an enantiomeric pair of stromelysin-1 inhibitors caused by conformational entropy factors

Bioorganic & medicinal chemistry letters, 2000-11, Vol.10 (21), p.2427-2430

2000

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The Role of 4-phosphonodifluoromethyl- and 4-phosphono-phenylalanine in the selectivity and cellular uptake of SH2 domain ligands

Bioorganic & medicinal chemistry letters, 1997-07, Vol.7 (14), p.1909-1914

1997

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Specificity in the binding of inhibitors to the active site of human/primate aspartic proteinases: analysis of P2-P1-P1'-P2' variation

Journal of medicinal chemistry, 1993-09, Vol.36 (18), p.2614-2620

1993

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Parameter estimation of random fields with long-range dependence

Mathematical and computer modelling, 1995-05, Vol.21 (9), p.67-77

1995

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Nonpeptidic HIV protease inhibitors: 6-alkyl-5, 6-dihydropyran-2-ones possessing achiral 3-(4-amino/carboxamide-2- t-butyl, 5-methylphenyl thio) moiety: Antiviral activities and pharmacokinetic properties

Bioorganic & medicinal chemistry letters, 1999-06, Vol.9 (11), p.1481-1486

1999

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X-ray structures of five renin inhibitors bound to saccharopepsin: exploration of active-site specificity

Journal of molecular biology, 2000-11, Vol.303 (5), p.745-760

2000

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Analyses of ligand binding in five endothiapepsin crystal complexes and their use in the design and evaluation of novel renin inhibitors

Journal of medicinal chemistry, 1993-11, Vol.36 (24), p.3809-3820

1993

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A state-of-the-art review and feasibility analysis of high altitude wind power in Northern Ireland

4-Hydroxy-5,6-dihydropyrones as Inhibitors of HIV Protease: The Effect of Heterocyclic Substituents at C-6 on Antiviral Potency and Pharmacokinetic Parameters

An Alpha-Mercaptoacrylic Acid Derivative is a Selective Nonpeptide Cell-Permeable Calpain Inhibitor and is Neuroprotective

Design, Synthesis, and Cocrystal Structure of a Nonpeptide Src SH2 Domain Ligand

4-Hydroxy-5,6-dihydropyrones. 2. Potent Non-Peptide Inhibitors of HIV Protease

5,6-Dihydropyran-2-ones Possessing Various Sulfonyl Functionalities: Potent Nonpeptidic Inhibitors of HIV Protease

A Novel Nonpeptide HIV-1 Protease Inhibitor: Elucidation of the Binding Mode and Its Application in the Design of Related Analogs

Synthesis of 5,6-Dihydro-4-hydroxy-2- pyrones as HIV-1 Protease Inhibitors: The Profound Effect of Polarity on Antiviral Activity

Statistical elements of predicting the impact of a variety of odour sources

Novel Series of Achiral, Low Molecular Weight, and Potent HIV-1 Protease Inhibitors

Analysis of the Binding of Hydroxamic Acid and Carboxylic Acid Inhibitors to the Stromelysin-1 (Matrix Metalloproteinase-3) Catalytic Domain by Isothermal Titration Calorimetry

Renin inhibitors containing isosteric replacements of the amide bond connecting the P3 and P2 sites

Computing in drug discovery: the design phase

Memories of metallothionein

Nonpeptidic HIV protease inhibitors possessing excellent antiviral activities and therapeutic indices. PD 178390 : A lead HIV protease inhibitor

Structure-based design of caspase-1 inhibitor containing a diphenyl ether sulfonamide

Nonpeptidic HIV protease inhibitors: 6-alkyl-5,6-dihydropyran-2-ones possessing a novel and achiral 3-(2- t-butyl-5-methyl-4-sulfamate)phenylthio moiety

X-ray crystallographic analysis of inhibition of endothiapepsin by cyclohexyl renin inhibitors

Stereoselective binding of an enantiomeric pair of stromelysin-1 inhibitors caused by conformational entropy factors

The Role of 4-phosphonodifluoromethyl- and 4-phosphono-phenylalanine in the selectivity and cellular uptake of SH2 domain ligands

Specificity in the binding of inhibitors to the active site of human/primate aspartic proteinases: analysis of P2-P1-P1'-P2' variation

Parameter estimation of random fields with long-range dependence

Nonpeptidic HIV protease inhibitors: 6-alkyl-5, 6-dihydropyran-2-ones possessing achiral 3-(4-amino/carboxamide-2- t-butyl, 5-methylphenyl thio) moiety: Antiviral activities and pharmacokinetic properties

X-ray structures of five renin inhibitors bound to saccharopepsin: exploration of active-site specificity

Analyses of ligand binding in five endothiapepsin crystal complexes and their use in the design and evaluation of novel renin inhibitors

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