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Topological data analysis for discovery in preclinical spinal cord injury and traumatic brain injury

Nature communications, 2015-10, Vol.6 (1), p.8581-8581, Article 8581

2015

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Innate and adaptive T cells in asthmatic patients: Relationship to severity and disease mechanisms

Journal of allergy and clinical immunology, 2015-08, Vol.136 (2), p.323-333

2015

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Integrative analysis of a cross-loci regulation network identifies App as a gene regulating insulin secretion from pancreatic islets

PLoS genetics, 2012-12, Vol.8 (12), p.e1003107-e1003107

2012

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Increasing the power to detect causal associations by combining genotypic and expression data in segregating populations

PLoS computational biology, 2007-04, Vol.3 (4), p.e69-e69

2007

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Topological data analysis of Escherichia coli O157:H7 and non-O157 survival in soils

Frontiers in cellular and infection microbiology, 2014-09, Vol.4, p.122

2014

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A Single Glycine Mutation in the Equilibrative Nucleoside Transporter Gene, hENT1, Alters Nucleoside Transport Activity and Sensitivity to Nitrobenzylthioinosine

Biochemistry (Easton), 2002-02, Vol.41 (5), p.1512-1519

2002

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Acridine Derivatives as Inhibitors of the IRE1α-XBP1 Pathway Are Cytotoxic to Human Multiple Myeloma

Molecular cancer therapeutics, 2016-09, Vol.15 (9), p.2055-2065

2016

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Common body mass index-associated variants confer risk of extreme obesity

Human molecular genetics, 2009-09, Vol.18 (18), p.3502-3507

2009

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Thematic review series: Systems Biology Approaches to Metabolic and Cardiovascular Disorders. Reverse engineering gene networks to identify key drivers of complex disease phenotypes

Journal of lipid research, 2006-12, Vol.47 (12), p.2601-2613

2006

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Integrative genomics and drug development

Pharmacogenomics, 2009-02, Vol.10 (2), p.203-212

2009

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Development of an Approach for Ab Initio Estimation of Compound-Induced Liver Injury Based on Global Gene Transcriptional Profiles

Genome Informatics, 2006, Vol.17(2), pp.77-88

2006

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Common body mass index-associated variants confer risk of extreme obesity

Human molecular genetics, 2010-09, Vol.19 (18), p.3690-3691

2010

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Increasing the Power to Detect Causal Associations among Genes and between Genes and Complex Traits by Combining Genotypic and Gene Expression Data in Segregating Populations

PLoS computational biology, 2005, Vol.preprint (2007), p.e69

2005

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Integrating genotypic and expression data in a segregating mouse population to identify 5-lipoxygenase as a susceptibility gene for obesity and bone traits

Nature genetics, 2005-11, Vol.37 (11), p.1224-1233

2005

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An integrative genomics approach to infer causal associations between gene expression and disease

Nature genetics, 2005-07, Vol.37 (7), p.710-717

2005

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Integrating QTL and high-density SNP analyses in mice to identify Insig2 as a susceptibility gene for plasma cholesterol levels

Genomics (San Diego, Calif.), 2005-11, Vol.86 (5), p.505-517

2005

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Discovering Modes of Action for Therapeutic Compounds Using a Genome-Wide Screen of Yeast Heterozygotes

Cell, 2004-01, Vol.116 (1), p.121-137

2004

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Clustering of Hepatotoxins Based on Mechanism of Toxicity Using Gene Expression Profiles

Toxicology and applied pharmacology, 2001-08, Vol.175 (1), p.28-42

2001

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A gene expression signature that classifies human atherosclerotic plaque by relative inflammation status

Circulation. Cardiovascular genetics, 2011-12, Vol.4 (6), p.595

2011

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Elucidating the murine brain transcriptional network in a segregating mouse population to identify core functional modules for obesity and diabetes

Journal of neurochemistry, 2006-04, Vol.97 (s1), p.50-62

2006

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Gene expression profiling of rat liver reveals a mechanistic basis for ritonavir-induced hyperlipidemia

Genomics (San Diego, Calif.), 2007-10, Vol.90 (4), p.464-473

2007

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From drug to protein: using yeast genetics for high-throughput target discovery

Current opinion in chemical biology, 2005-02, Vol.9 (1), p.20-24

2005

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Parallel analysis of tagged deletion mutants efficiently identifies genes involved in endoplasmic reticulum biogenesis

Yeast (Chichester, England), 2003-07, Vol.20 (10), p.881-892

2003

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Topological data analysis for discovery in preclinical spinal cord injury and traumatic brain injury

Innate and adaptive T cells in asthmatic patients: Relationship to severity and disease mechanisms

Integrative analysis of a cross-loci regulation network identifies App as a gene regulating insulin secretion from pancreatic islets

Increasing the power to detect causal associations by combining genotypic and expression data in segregating populations

Mapping the genetic architecture of gene expression in human liver

Topological data analysis of Escherichia coli O157:H7 and non-O157 survival in soils

A Single Glycine Mutation in the Equilibrative Nucleoside Transporter Gene, hENT1, Alters Nucleoside Transport Activity and Sensitivity to Nitrobenzylthioinosine

Acridine Derivatives as Inhibitors of the IRE1α-XBP1 Pathway Are Cytotoxic to Human Multiple Myeloma

Common body mass index-associated variants confer risk of extreme obesity

Thematic review series: Systems Biology Approaches to Metabolic and Cardiovascular Disorders. Reverse engineering gene networks to identify key drivers of complex disease phenotypes

Integrative genomics and drug development

Development of an Approach for Ab Initio Estimation of Compound-Induced Liver Injury Based on Global Gene Transcriptional Profiles

Common body mass index-associated variants confer risk of extreme obesity

Validation of Candidate Causal Genes for Abdominal Obesity Which Affect Shared Metabolic Pathways and Networks

Increasing the Power to Detect Causal Associations among Genes and between Genes and Complex Traits by Combining Genotypic and Gene Expression Data in Segregating Populations

Integrating genotypic and expression data in a segregating mouse population to identify 5-lipoxygenase as a susceptibility gene for obesity and bone traits

An integrative genomics approach to infer causal associations between gene expression and disease

Integrating QTL and high-density SNP analyses in mice to identify Insig2 as a susceptibility gene for plasma cholesterol levels

Discovering Modes of Action for Therapeutic Compounds Using a Genome-Wide Screen of Yeast Heterozygotes

Clustering of Hepatotoxins Based on Mechanism of Toxicity Using Gene Expression Profiles

A gene expression signature that classifies human atherosclerotic plaque by relative inflammation status

Elucidating the murine brain transcriptional network in a segregating mouse population to identify core functional modules for obesity and diabetes

Gene expression profiling of rat liver reveals a mechanistic basis for ritonavir-induced hyperlipidemia

From drug to protein: using yeast genetics for high-throughput target discovery

Parallel analysis of tagged deletion mutants efficiently identifies genes involved in endoplasmic reticulum biogenesis

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