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Chemical biology of anticancer gold(iii) and gold(i) complexes

Chemical Society reviews, 2015-12, Vol.44 (24), p.8786-881

2015

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Specific inhibitors of the protein tyrosine phosphatase Shp2 identified by high-throughput docking

Proceedings of the National Academy of Sciences - PNAS, 2008-05, Vol.105 (20), p.7275-7280

2008

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Gold(III) Complexes Containing N-Heterocyclic Carbene Ligands: Thiol "Switch-on" Fluorescent Probes and Anti-Cancer Agents

Angewandte Chemie International Edition, 2013-03, Vol.52 (10), p.2930-2933

International ed. in English, 2013

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IFITM1 promotes the metastasis of human colorectal cancer via CAV-1

Cancer letters, 2015-11, Vol.368 (1), p.135-143

2015

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Allograft inflammatory factor-1 (AIF-1) is crucial for the survival and pro-inflammatory activity of macrophages

International immunology, 2005-11, Vol.17 (11), p.1391-1397

2005

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Restoration of XAF1 expression induces apoptosis and inhibits tumor growth in gastric cancer

International journal of cancer, 2009-08, Vol.125 (3), p.688-697

2009

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Potent inhibition of SARS-associated coronavirus (SCOV) infection and replication by type I interferons (IFN-alpha/beta) but not by type II interferon (IFN-gamma)

Journal of interferon & cytokine research, 2004-07, Vol.24 (7), p.388-390

2004

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Suppression of survivin expression inhibits in vivo tumorigenicity and angiogenesis in gastric cancer

Cancer research (Chicago, Ill.), 2003-11, Vol.63 (22), p.7724-7732

2003

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Identification of brain-derived neurotrophic factor as a novel functional protein in hepatocellular carcinoma

Cancer research (Chicago, Ill.), 2005, Vol.65 (1), p.219-225

2005

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Psychometric Evaluation of the PNH Symptom Questionnaire (PNH-SQ) Among Patients with Paroxysmal Nocturnal Hemoglobinuria from Three Phase 2 Clinical Trials with Pozelimab Monotherapy or in Combination with Cemdisiran

Blood, 2023-11, Vol.142 (Supplement 1), p.3752-3752

2023

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Gold(III) compound is a novel chemocytotoxic agent for hepatocellular carcinoma

International journal of cancer, 2006-03, Vol.118 (6), p.1527-1538

2006

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A Binuclear Gold(I) Complex with Mixed Bridging Diphosphine and Bis(N-Heterocyclic Carbene) Ligands Shows Favorable Thiol Reactivity and Inhibits Tumor Growth and Angiogenesis In Vivo

Angewandte Chemie International Edition, 2014-06, Vol.53 (23), p.5810-5814

2014

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PLASMIC Score to Aid Diagnosis of Atypical Hemolytic Uremic Syndrome: A Post Hoc Analysis of Data From C5 Inhibitor Trials: TH-PO501

Journal of the American Society of Nephrology, 2022-11, Vol.33 (11S), p.188-189

2022

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Gold(iii) complexes inhibit growth of cisplatin-resistant ovarian cancer in association with upregulation of proapoptotic PMS2 gene

Chemical science (Cambridge), 2014-01, Vol.5 (4), p.1579

2014

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Use of Plasmic Scores to Aid Diagnosis of aHUS: A Real-World Analysis of Hospitalized Patients from the Premier Healthcare Database

Blood, 2022-11, Vol.140 (Supplement 1), p.2780-2781

2022

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Luminescent Cyclometalated Platinum(II) Complex Forms Emissive Intercalating Adducts with Double-Stranded DNA and RNA: Differential Emissions and Anticancer Activities

Angewandte Chemie International Edition, 2014-09, Vol.53 (38), p.10119-10123

International ed. in English, 2014

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Alkynyl gold(I) phosphane complexes: Evaluation of structure–activity-relationships for the phosphane ligands, effects on key signaling proteins and preliminary in-vivo studies with a nanoformulated complex

Journal of inorganic biochemistry, 2016-07, Vol.160, p.140-148

2016

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A gold(III) porphyrin complex as an anti-cancer candidate to inhibit growth of cancer-stem cells

Chemical communications (Cambridge, England), 2013-05, Vol.49 (39), p.4364-4366

2013

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Shotgun Proteomics and Quantitative Pathway Analysis of the Mechanisms of Action of Dehydroeffusol, a Bioactive Phytochemical with Anticancer Activity from Juncus effusus

Journal of proteome research, 2018-07, Vol.17 (7), p.2470-2479

2018

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A Binuclear Gold(I) Complex with Mixed Bridging Diphosphine and Bis(N-Heterocyclic Carbene) Ligands Shows Favorable Thiol Reactivity and Inhibits Tumor Growth and Angiogenesis InVivo

Angewandte Chemie International Edition, 2014-06, Vol.53 (23), p.5810-5814

International ed. in English, 2014

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A gold(iii) porphyrin complex as an anti-cancer candidate to inhibit growth of cancer-stem cellsThis article is part of the ChemComm 'Emerging Investigators 2013' themed issue.Electronic supplementary information (ESI) available: Synthesis and characterization of gold-1a; detailed biological experimental procedures; supplementary figures/table; references. See DOI: 10.1039/c2cc37366a

2013-04

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The Correction of Product Information in Drug References and Medical Textbooks

Drug information journal, 2012-01, Vol.46 (1), p.94-98

2012

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Gold(III) porphyrin 1a inhibited nasopharyngeal carcinoma metastasis in vivo and inhibited cell migration and invasion in vitro

Cancer letters, 2010-08, Vol.294 (2), p.159-166

2010

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Gold(III) porphyrin 1a prolongs the survival of melanoma-bearing mice and inhibits angiogenesis

Acta oncologica, 2011-06, Vol.50 (5), p.719-726

2011

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A Binuclear Gold(I) Complex with Mixed Bridging Diphosphine and Bis(N-Heterocyclic Carbene) Ligands Shows Favorable Thiol Reactivity and Inhibits Tumor Growth and Angiogenesis InVivo

Angewandte Chemie, 2014-06, Vol.126 (23), p.5920-5924

2014

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Chemical biology of anticancer gold(iii) and gold(i) complexes

Specific inhibitors of the protein tyrosine phosphatase Shp2 identified by high-throughput docking

Gold(III) Complexes Containing N-Heterocyclic Carbene Ligands: Thiol "Switch-on" Fluorescent Probes and Anti-Cancer Agents

IFITM1 promotes the metastasis of human colorectal cancer via CAV-1

Allograft inflammatory factor-1 (AIF-1) is crucial for the survival and pro-inflammatory activity of macrophages

Restoration of XAF1 expression induces apoptosis and inhibits tumor growth in gastric cancer

Potent inhibition of SARS-associated coronavirus (SCOV) infection and replication by type I interferons (IFN-alpha/beta) but not by type II interferon (IFN-gamma)

Suppression of survivin expression inhibits in vivo tumorigenicity and angiogenesis in gastric cancer

Identification of brain-derived neurotrophic factor as a novel functional protein in hepatocellular carcinoma

Psychometric Evaluation of the PNH Symptom Questionnaire (PNH-SQ) Among Patients with Paroxysmal Nocturnal Hemoglobinuria from Three Phase 2 Clinical Trials with Pozelimab Monotherapy or in Combination with Cemdisiran

Gold(III) compound is a novel chemocytotoxic agent for hepatocellular carcinoma

A Binuclear Gold(I) Complex with Mixed Bridging Diphosphine and Bis(N-Heterocyclic Carbene) Ligands Shows Favorable Thiol Reactivity and Inhibits Tumor Growth and Angiogenesis In Vivo

PLASMIC Score to Aid Diagnosis of Atypical Hemolytic Uremic Syndrome: A Post Hoc Analysis of Data From C5 Inhibitor Trials: TH-PO501

Gold(iii) complexes inhibit growth of cisplatin-resistant ovarian cancer in association with upregulation of proapoptotic PMS2 gene

Use of Plasmic Scores to Aid Diagnosis of aHUS: A Real-World Analysis of Hospitalized Patients from the Premier Healthcare Database

Luminescent Cyclometalated Platinum(II) Complex Forms Emissive Intercalating Adducts with Double-Stranded DNA and RNA: Differential Emissions and Anticancer Activities

Alkynyl gold(I) phosphane complexes: Evaluation of structure–activity-relationships for the phosphane ligands, effects on key signaling proteins and preliminary in-vivo studies with a nanoformulated complex

A gold(III) porphyrin complex as an anti-cancer candidate to inhibit growth of cancer-stem cells

Shotgun Proteomics and Quantitative Pathway Analysis of the Mechanisms of Action of Dehydroeffusol, a Bioactive Phytochemical with Anticancer Activity from Juncus effusus

A Binuclear Gold(I) Complex with Mixed Bridging Diphosphine and Bis(N-Heterocyclic Carbene) Ligands Shows Favorable Thiol Reactivity and Inhibits Tumor Growth and Angiogenesis InVivo

The Correction of Product Information in Drug References and Medical Textbooks

Gold(III) porphyrin 1a inhibited nasopharyngeal carcinoma metastasis in vivo and inhibited cell migration and invasion in vitro

Gold(III) porphyrin 1a prolongs the survival of melanoma-bearing mice and inhibits angiogenesis

A Binuclear Gold(I) Complex with Mixed Bridging Diphosphine and Bis(N-Heterocyclic Carbene) Ligands Shows Favorable Thiol Reactivity and Inhibits Tumor Growth and Angiogenesis InVivo

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