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A hidden gene in astroviruses encodes a viroporin

Nature communications, 2020-08, Vol.11 (1), p.4070-4070, Article 4070

2020

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The astrovirus N-terminal nonstructural protein anchors replication complexes to the perinuclear ER membranes

PLoS pathogens, 2024-07, Vol.20 (7), p.e1011959

2024

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Attenuation hotspots in neurotropic human astroviruses

PLoS biology, 2023-07, Vol.21 (7), p.e3001815

2023

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Novel Attenuated Chikungunya Vaccine Candidates Elicit Protective Immunity in C57BL/6 mice

Journal of Virology, 2014-03, Vol.88 (5), p.2858-2866

2014

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Mutations conferring a noncytotoxic phenotype on chikungunya virus replicons compromise enzymatic properties of nonstructural protein 2

Journal of virology, 2015-03, Vol.89 (6), p.3145-3162

2015

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Safe and Effective Treatment of Experimental Neuroblastoma and Glioblastoma Using Systemically Delivered Triple MicroRNA-Detargeted Oncolytic Semliki Forest Virus

Clinical cancer research, 2017-03, Vol.23 (6), p.1519-1530

2017

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Macromolecular Assembly-Driven Processing of the 2/3 Cleavage Site in the Alphavirus Replicase Polyprotein

Journal of Virology, 2012-01, Vol.86 (1), p.553-565

2012

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Prime-boost immunization strategies against Chikungunya virus

Journal of virology, 2014-11, Vol.88 (22), p.13333-13343

2014

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An upstream protein-coding region in enteroviruses modulates virus infection in gut epithelial cells

Nature microbiology, 2019-02, Vol.4 (2), p.280-292

2019

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RIG-I and MDA-5 detection of viral RNA-dependent RNA polymerase activity restricts positive-strand RNA virus replication

PLoS pathogens, 2013-09, Vol.9 (9), p.e1003610-e1003610

2013

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Zika viruses encode 5′ upstream open reading frames affecting infection of human brain cells

Nature communications, 2024-10, Vol.15 (1), p.8822-19, Article 8822

2024

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Mutation of CD2AP and SH3KBP1 Binding Motif in Alphavirus nsP3 Hypervariable Domain Results in Attenuated Virus

Viruses, 2018-04, Vol.10 (5), p.226

2018

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Understanding neurotropic enteric viruses: routes of infection and mechanisms of attenuation

Cellular and molecular life sciences : CMLS, 2024-12, Vol.81 (1), p.413, Article 413

2024

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Presentation Overrides Specificity: Probing the Plasticity of Alphaviral Proteolytic Activity through Mutational Analysis

Journal of Virology, 2013-09, Vol.87 (18), p.10207-10220

2013

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The Amino-Terminal Domain of Alphavirus Capsid Protein Is Dispensable for Viral Particle Assembly but Regulates RNA Encapsidation through Cooperative Functions of Its Subdomains

Journal of Virology, 2013-11, Vol.87 (22), p.12003-12019

2013

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Loss of TLR3 aggravates CHIKV replication and pathology due to an altered virus‐specific neutralizing antibody response

EMBO molecular medicine, 2015-01, Vol.7 (1), p.24-41

2015

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Enterovirus Competition Assay to Assess Replication Fitness

Bio-protocol, 2019-06, Vol.9 (10)

2019

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Virus replicon particle based Chikungunya virus neutralization assay using Gaussia luciferase as readout

Virology journal, 2013-07, Vol.10 (1), p.235-235, Article 235

2013

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Molecular Determinants of Substrate Specificity for Semliki Forest Virus Nonstructural Protease

Journal of Virology, 2006-06, Vol.80 (11), p.5413-5422

2006

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The SARS-CoV-2 protein ORF3c is a mitochondrial modulator of innate immunity

iScience, 2023-11, Vol.26 (11), p.108080, Article 108080

2023

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Molecular Defects Caused by Temperature-Sensitive Mutations in Semliki Forest Virus nsP1

Journal of Virology, 2008-09, Vol.82 (18), p.9236-9244

2008

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IFN-α/β Detection Assay Using Sensor Cell Lines

Bio-protocol, 2014-05, Vol.4 (10)

2014

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Timeliness of Proteolytic Events Is Prerequisite for Efficient Functioning of the Alphaviral Replicase

Journal of virology, 2018-07, Vol.92 (14)

2018

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Semliki Forest Virus Chimeras with Functional Replicase Modules from Related Alphaviruses Survive by Adaptive Mutations in Functionally Important Hot Spots

Journal of virology, 2021-09, Vol.95 (20), p.e0097321

2021

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A pathogenic role for CD4+ T cells during Chikungunya virus infection in mice

The Journal of immunology (1950), 2013-01, Vol.190 (1), p.259-269

2013

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A hidden gene in astroviruses encodes a viroporin

The astrovirus N-terminal nonstructural protein anchors replication complexes to the perinuclear ER membranes

Attenuation hotspots in neurotropic human astroviruses

Novel Attenuated Chikungunya Vaccine Candidates Elicit Protective Immunity in C57BL/6 mice

Mutations conferring a noncytotoxic phenotype on chikungunya virus replicons compromise enzymatic properties of nonstructural protein 2

Safe and Effective Treatment of Experimental Neuroblastoma and Glioblastoma Using Systemically Delivered Triple MicroRNA-Detargeted Oncolytic Semliki Forest Virus

Macromolecular Assembly-Driven Processing of the 2/3 Cleavage Site in the Alphavirus Replicase Polyprotein

Prime-boost immunization strategies against Chikungunya virus

An upstream protein-coding region in enteroviruses modulates virus infection in gut epithelial cells

RIG-I and MDA-5 detection of viral RNA-dependent RNA polymerase activity restricts positive-strand RNA virus replication

Zika viruses encode 5′ upstream open reading frames affecting infection of human brain cells

Mutation of CD2AP and SH3KBP1 Binding Motif in Alphavirus nsP3 Hypervariable Domain Results in Attenuated Virus

Understanding neurotropic enteric viruses: routes of infection and mechanisms of attenuation

Presentation Overrides Specificity: Probing the Plasticity of Alphaviral Proteolytic Activity through Mutational Analysis

The Amino-Terminal Domain of Alphavirus Capsid Protein Is Dispensable for Viral Particle Assembly but Regulates RNA Encapsidation through Cooperative Functions of Its Subdomains

Loss of TLR3 aggravates CHIKV replication and pathology due to an altered virus‐specific neutralizing antibody response

Enterovirus Competition Assay to Assess Replication Fitness

Virus replicon particle based Chikungunya virus neutralization assay using Gaussia luciferase as readout

Molecular Determinants of Substrate Specificity for Semliki Forest Virus Nonstructural Protease

The SARS-CoV-2 protein ORF3c is a mitochondrial modulator of innate immunity

Molecular Defects Caused by Temperature-Sensitive Mutations in Semliki Forest Virus nsP1

IFN-α/β Detection Assay Using Sensor Cell Lines

Timeliness of Proteolytic Events Is Prerequisite for Efficient Functioning of the Alphaviral Replicase

Semliki Forest Virus Chimeras with Functional Replicase Modules from Related Alphaviruses Survive by Adaptive Mutations in Functionally Important Hot Spots

A pathogenic role for CD4+ T cells during Chikungunya virus infection in mice

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