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Role of Dopamine Receptors in the Anticancer Activity of ONC201

Neoplasia (New York, N.Y.), 2018-01, Vol.20 (1), p.80-91

2018

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miR-6883 Family miRNAs Target CDK4/6 to Induce G1 Phase Cell-Cycle Arrest in Colon Cancer Cells

Cancer research (Chicago, Ill.), 2017-12, Vol.77 (24), p.6902-6913

2017

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Cancer stem cell-related gene expression as a potential biomarker of response for first-in-class imipridone ONC201 in solid tumors

PloS one, 2017-08, Vol.12 (8), p.e0180541

2017

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Small-Molecule Prodigiosin Restores p53 Tumor Suppressor Activity in Chemoresistant Colorectal Cancer Stem Cells via c-Jun-Mediated ΔNp73 Inhibition and p73 Activation

Cancer research (Chicago, Ill.), 2016-04, Vol.76 (7), p.1989-1999

2016

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Neutrophil Elastase Remodels Mammary Tumors to Facilitate Lung Metastasis

Molecular cancer therapeutics, 2024-04, Vol.23 (4), p.492

2024

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P53-independent partial restoration of the p53 pathway in tumors with mutated p53 through ATF4 transcriptional modulation by ERK1/2 and CDK9

Neoplasia (New York, N.Y.), 2021-03, Vol.23 (3), p.304-325

2021

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Anti-pancreatic cancer activity of ONC212 involves the unfolded protein response (UPR) and is reduced by IGF1-R and GRP78/BIP

Oncotarget, 2017-10, Vol.8 (47), p.81776-81793

2017

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Preclinical rationale for combination of crizotinib with mitomycin C for the treatment of advanced colorectal cancer

Cancer biology & therapy, 2017-09, Vol.18 (9), p.694-704

2017

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Preclinical evaluation of the imipridone family, analogs of clinical stage anti-cancer small molecule ONC201, reveals potent anti-cancer effects of ONC212

Cell cycle (Georgetown, Tex.), 2017-10, Vol.16 (19), p.1790-1799

2017

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ONC201 Targets AR and AR-V7 Signaling, Reduces PSA, and Synergizes with Everolimus in Prostate Cancer

Molecular cancer research, 2018-05, Vol.16 (5), p.754-766

2018

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Single agent and synergistic combinatorial efficacy of first-in-class small molecule imipridone ONC201 in hematological malignancies

Cell cycle (Georgetown, Tex.), 2018-01, Vol.17 (4), p.468-478

2018

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ONC201: a new treatment option being tested clinically for recurrent glioblastoma

Translational cancer research, 2017-10, Vol.6 (S7), p.S1239-S1243

2017

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Bcl-2 Protein Targeting by the p53/p21 Complex-Letter

Cancer research (Chicago, Ill.), 2018-05, Vol.78 (10), p.2770-2771

2018

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MMR-deficiency and BRCA2/EGFR/NTRK mutations

Aging (Albany, NY.), 2017-08, Vol.9 (8), p.1849-1850

2017

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Current treatment of early breast cancer: adjuvant and neoadjuvant therapy [version 1; peer review: 2 approved]

F1000 research, 2014, Vol.3, p.198-198

2014

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LMW cyclin E and its novel catalytic partner CDK5 are therapeutic targets and prognostic biomarkers in salivary gland cancers

Oncogenesis (New York, NY), 2021-05, Vol.10 (5), p.40-40, Article 40

2021

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miR-3132 upregulates surface TRAIL to induce apoptotic cell death in cancer cells

American journal of cancer research, 2022-01, Vol.12 (1), p.315-326

2022

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Abstract 2497: ONC201 targets cancer stem cells in colorectal, prostate and glioblastoma multiforme tumors via modulation of stem cell-related gene expression

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.2497-2497

2016

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Abstract 2154: P53 pathway restoring compound P306 inhibits colorectal cancer growth

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.2154-2154

2017

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Abstract P3-10-02: Neutrophil elastase as a therapeutic target to inhibit metastasis in breast cancer

Cancer research (Chicago, Ill.), 2020-02, Vol.80 (4_Supplement), p.P3-P3-10-02

2020

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Abstract 4289: Involvement of the miR-6883 family and the circadian rhythm gene PER1 in the DNA damage response (DDR) and chemosensitivity

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.4289-4289

2018

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Abstract 5455: Novel miRNA-based therapeutic approach to selectively target mutant p53 in cancer

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.5455-5455

2017

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Abstract 2102: ONC201 targets AR and AR-V7 signaling pathways, reduces PSA and synergizes with everolimus in castration resistant prostate cancer

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.2102-2102

2017

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Abstract 1067: Anti-cancer efficacy of imipridones in pancreatic cancer: single agent ONC212 or combination of ONC201 with IGF1-R inhibition

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.1067-1067

2017

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Role of Dopamine Receptors in the Anticancer Activity of ONC201

miR-6883 Family miRNAs Target CDK4/6 to Induce G1 Phase Cell-Cycle Arrest in Colon Cancer Cells

Cancer stem cell-related gene expression as a potential biomarker of response for first-in-class imipridone ONC201 in solid tumors

Small-Molecule Prodigiosin Restores p53 Tumor Suppressor Activity in Chemoresistant Colorectal Cancer Stem Cells via c-Jun-Mediated ΔNp73 Inhibition and p73 Activation

Neutrophil Elastase Remodels Mammary Tumors to Facilitate Lung Metastasis

P53-independent partial restoration of the p53 pathway in tumors with mutated p53 through ATF4 transcriptional modulation by ERK1/2 and CDK9

Anti-pancreatic cancer activity of ONC212 involves the unfolded protein response (UPR) and is reduced by IGF1-R and GRP78/BIP

Preclinical rationale for combination of crizotinib with mitomycin C for the treatment of advanced colorectal cancer

Discovery and clinical introduction of first-in-class imipridone ONC201

Preclinical evaluation of the imipridone family, analogs of clinical stage anti-cancer small molecule ONC201, reveals potent anti-cancer effects of ONC212

ONC201 Targets AR and AR-V7 Signaling, Reduces PSA, and Synergizes with Everolimus in Prostate Cancer

Single agent and synergistic combinatorial efficacy of first-in-class small molecule imipridone ONC201 in hematological malignancies

ONC201: a new treatment option being tested clinically for recurrent glioblastoma

Bcl-2 Protein Targeting by the p53/p21 Complex-Letter

MMR-deficiency and BRCA2/EGFR/NTRK mutations

Current treatment of early breast cancer: adjuvant and neoadjuvant therapy [version 1; peer review: 2 approved]

LMW cyclin E and its novel catalytic partner CDK5 are therapeutic targets and prognostic biomarkers in salivary gland cancers

miR-3132 upregulates surface TRAIL to induce apoptotic cell death in cancer cells

Abstract 2497: ONC201 targets cancer stem cells in colorectal, prostate and glioblastoma multiforme tumors via modulation of stem cell-related gene expression

Abstract 2154: P53 pathway restoring compound P306 inhibits colorectal cancer growth

Abstract P3-10-02: Neutrophil elastase as a therapeutic target to inhibit metastasis in breast cancer

Abstract 4289: Involvement of the miR-6883 family and the circadian rhythm gene PER1 in the DNA damage response (DDR) and chemosensitivity

Abstract 5455: Novel miRNA-based therapeutic approach to selectively target mutant p53 in cancer

Abstract 2102: ONC201 targets AR and AR-V7 signaling pathways, reduces PSA and synergizes with everolimus in castration resistant prostate cancer

Abstract 1067: Anti-cancer efficacy of imipridones in pancreatic cancer: single agent ONC212 or combination of ONC201 with IGF1-R inhibition

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