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Fumarates promote cytoprotection of central nervous system cells against oxidative stress via the nuclear factor (erythroid-derived 2)-like 2 pathway

The Journal of pharmacology and experimental therapeutics, 2012-04, Vol.341 (1), p.274-284

2012

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Fumaric acid esters exert neuroprotective effects in neuroinflammation via activation of the Nrf2 antioxidant pathway

Brain (London, England : 1878), 2011-03, Vol.134 (3), p.678-692

2011

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Small molecules inhibit the interaction of Nrf2 and the Keap1 Kelch domain through a non-covalent mechanism

Bioorganic & medicinal chemistry, 2013-07, Vol.21 (14), p.4011-4019

2013

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TRAF3 Controls Activation of the Canonical and Alternative NFκB by the Lymphotoxin Beta Receptor

The Journal of biological chemistry, 2010-04, Vol.285 (17), p.12971-12978

2010

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Partial Inhibition of Integrin αvβ6 Prevents Pulmonary Fibrosis without Exacerbating Inflammation

American journal of respiratory and critical care medicine, 2008, Vol.177 (1), p.56-65

2008

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Pharmacodynamics of Dimethyl Fumarate Are Tissue Specific and Involve NRF2-Dependent and -Independent Mechanisms

Antioxidants & redox signaling, 2016-06, Vol.24 (18), p.1058-1071

2016

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Inhibition of Integrin αvβ6, an Activator of Latent Transforming Growth Factor-β, Prevents Radiation-induced Lung Fibrosis

American journal of respiratory and critical care medicine, 2008-01, Vol.177 (1), p.82-90

2008

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ECM signalling: orchestrating cell behaviour and misbehaviour

Trends in Cell Biology, 1998-11, Vol.8 (11), p.437-441

1998

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αvβ6 Integrin Regulates Renal Fibrosis and Inflammation in Alport Mouse

The American journal of pathology, 2007, Vol.170 (1), p.110-125

2007

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Pristane-Accelerated Autoimmune Disease in (SWR X NZB) F1 Mice Leads to Prominent Tubulointerstitial Inflammation and Human Lupus Nephritis-Like Fibrosis

PloS one, 2016-10, Vol.11 (10), p.e0164423-e0164423

2016

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Regulation of Integrin Function by the Urokinase Receptor

Science (American Association for the Advancement of Science), 1996-09, Vol.273 (5281), p.1551-1555

1996

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Dual role for TWEAK in angiogenic regulation

Journal of cell science, 2002-01, Vol.115 (Pt 2), p.267-274

2002

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A Placebo-Controlled Phase I Study of NVG-291 in Healthy Subjects, Targeting CNS Receptor Protein Tyrosine Phosphatase Sigma (PTPσ) (S8.009)

Neurology, 2022-05, Vol.98 (18_supplement)

2022

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Fumaric acid esters exert neuroprotective effects in neuroinflammation via activation of the Nrf2 antioxidant pathway

Brain (London, England : 1878), 2011-03, Vol.134 (Pt 3), p.678-692

2011

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A Placebo‐Controlled Phase I Study in Healthy Subjects Assessing NVG‐291, which Targets CNS Receptor Protein Tyrosine Phosphatase Sigma (PTPσ)

Alzheimer's & dementia, 2022-12, Vol.18 (S10), p.n/a

2022

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Topology of gene expression networks as revealed by data mining and modeling

Bioinformatics, 2003-10, Vol.19 (15), p.1909-1916

2003

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Pristane-Accelerated Autoimmune Disease in

PloS one, 2016-10, Vol.11 (10), p.e0164423

2016

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BG-12 (Dimethyl Fumarate) Pharmacodynamic Responses Have Distinct Temporal Profiles and Are Dose-Dependent (P05.146)

Neurology, 2013-02, Vol.80 (7_supplement)

2013

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Targeting the lymphotoxin-β receptor with agonist antibodies as a potential cancer therapy

Cancer research (Chicago, Ill.), 2006-10, Vol.66 (19), p.9617-9624

2006

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Perturbation of β1-integrin function alters the development of murine mammary gland

The EMBO journal, 1998-04, Vol.17 (8), p.2139-2147

1998

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Disruption of integrin function and induction of tyrosine phosphorylation by the autonomously expressed β1 integrin cytoplasmic domain

The Journal of biological chemistry, 1994-07, Vol.269 (28), p.18311-18314

1994

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Human and Mouse IFN-β Gene Therapy Exhibits Different Anti-tumor Mechanisms in Mouse Models

Molecular therapy, 2001-10, Vol.4 (4), p.356-364

2001

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Inhibition of Integrin ¿vß6, an Activator of Latent Transforming Growth Factor-ß, Prevents Radiation-induced Lung Fibrosis

American journal of respiratory and critical care medicine, 2008-01, Vol.177 (1), p.82

2008

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Partial Inhibition of Integrin ¿vß6 Prevents Pulmonary Fibrosis without Exacerbating Inflammation

American journal of respiratory and critical care medicine, 2008-01, Vol.177 (1), p.56

2008

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Synthesis of heat-shock proteins in cultured fibroblasts from normotensive and spontaneously hypertensive rat embryos

Journal of hypertension, 1991-12, Vol.9 Suppl 6 (6), p.S184-S184

1991

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Fumarates promote cytoprotection of central nervous system cells against oxidative stress via the nuclear factor (erythroid-derived 2)-like 2 pathway

Fumaric acid esters exert neuroprotective effects in neuroinflammation via activation of the Nrf2 antioxidant pathway

Small molecules inhibit the interaction of Nrf2 and the Keap1 Kelch domain through a non-covalent mechanism

TRAF3 Controls Activation of the Canonical and Alternative NFκB by the Lymphotoxin Beta Receptor

Partial Inhibition of Integrin αvβ6 Prevents Pulmonary Fibrosis without Exacerbating Inflammation

Pharmacodynamics of Dimethyl Fumarate Are Tissue Specific and Involve NRF2-Dependent and -Independent Mechanisms

Inhibition of Integrin αvβ6, an Activator of Latent Transforming Growth Factor-β, Prevents Radiation-induced Lung Fibrosis

ECM signalling: orchestrating cell behaviour and misbehaviour

αvβ6 Integrin Regulates Renal Fibrosis and Inflammation in Alport Mouse

Pristane-Accelerated Autoimmune Disease in (SWR X NZB) F1 Mice Leads to Prominent Tubulointerstitial Inflammation and Human Lupus Nephritis-Like Fibrosis

Regulation of Integrin Function by the Urokinase Receptor

Dual role for TWEAK in angiogenic regulation

A Placebo-Controlled Phase I Study of NVG-291 in Healthy Subjects, Targeting CNS Receptor Protein Tyrosine Phosphatase Sigma (PTPσ) (S8.009)

Fumaric acid esters exert neuroprotective effects in neuroinflammation via activation of the Nrf2 antioxidant pathway

A Placebo‐Controlled Phase I Study in Healthy Subjects Assessing NVG‐291, which Targets CNS Receptor Protein Tyrosine Phosphatase Sigma (PTPσ)

Topology of gene expression networks as revealed by data mining and modeling

Pristane-Accelerated Autoimmune Disease in

BG-12 (Dimethyl Fumarate) Pharmacodynamic Responses Have Distinct Temporal Profiles and Are Dose-Dependent (P05.146)

Targeting the lymphotoxin-β receptor with agonist antibodies as a potential cancer therapy

Perturbation of β1-integrin function alters the development of murine mammary gland

Disruption of integrin function and induction of tyrosine phosphorylation by the autonomously expressed β1 integrin cytoplasmic domain

Human and Mouse IFN-β Gene Therapy Exhibits Different Anti-tumor Mechanisms in Mouse Models

Inhibition of Integrin ¿vß6, an Activator of Latent Transforming Growth Factor-ß, Prevents Radiation-induced Lung Fibrosis

Partial Inhibition of Integrin ¿vß6 Prevents Pulmonary Fibrosis without Exacerbating Inflammation

Synthesis of heat-shock proteins in cultured fibroblasts from normotensive and spontaneously hypertensive rat embryos

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