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Intracellular routing of plasmid DNA during non-viral gene transfer

Advanced drug delivery reviews, 2005-04, Vol.57 (5), p.755-767

2005

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Metabolic instability of plasmid DNA in the cytosol : a potential barrier to gene transfer

Gene therapy, 1999-04, Vol.6 (4), p.482-497

1999

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Nucleocytoplasmic transport of plasmid DNA: a perilous journey from the cytoplasm to the nucleus

Human gene therapy, 2006-09, Vol.17 (9), p.882-889

2006

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C-terminal truncations destabilize the cystic fibrosis transmembrane conductance regulator without impairing its biogenesis. A novel class of mutation

The Journal of biological chemistry, 1999-07, Vol.274 (31), p.21873-21877

1999

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The delta F508 mutation decreases the stability of cystic fibrosis transmembrane conductance regulator in the plasma membrane. Determination of functional half-lives on transfected cells

The Journal of biological chemistry, 1993-10, Vol.268 (29), p.21592-21598

1993

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Curcumin, a Major Constituent of Turmeric, Corrects Cystic Fibrosis Defects

Science (American Association for the Advancement of Science), 2004-04, Vol.304 (5670), p.600-602

2004

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Intracellular barriers to non-viral gene transfer

Current gene therapy, 2002-05, Vol.2 (2), p.183-194

2002

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Size-dependent DNA Mobility in Cytoplasm and Nucleus

The Journal of biological chemistry, 2000-01, Vol.275 (3), p.1625-1629

2000

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Determinants of the Nuclear Localization of the Heterodimeric DNA Fragmentation Factor (ICAD/CAD)

The Journal of cell biology, 2000-07, Vol.150 (2), p.321-334

2000

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Multiple endocytic signals in the C-terminal tail of the cystic fibrosis transmembrane conductance regulator

Biochemical journal, 2001-03, Vol.354 (Pt 3), p.561-572

2001

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Phagosomal acidification is mediated by a vacuolar-type H(+)-ATPase in murine macrophages

The Journal of biological chemistry, 1990-12, Vol.265 (34), p.21099-21107

1990

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Conformational and Temperature-sensitive Stability Defects of the ΔF508 Cystic Fibrosis Transmembrane Conductance Regulator in Post-endoplasmic Reticulum Compartments

The Journal of biological chemistry, 2001-03, Vol.276 (12), p.8942-8950

2001

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Ubiquitin-dependent sorting in endocytosis

Cold Spring Harbor perspectives in biology, 2014-01, Vol.6 (1), p.a016808-a016808

2014

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Proton conductance of the plasma membrane: properties, regulation, and functional role

American Journal of Physiology: Cell Physiology, 1993-07, Vol.265 (1), p.C3-C14

1993

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The cystic fibrosis transmembrane regulator is present and functional in endosomes. Role as a determinant of endosomal pH

The Journal of biological chemistry, 1992-07, Vol.267 (21), p.14568-14572

1992

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Limited proteolysis as a probe for arrested conformational maturation of ΔF508 CFTR

Nature structural biology, 1998-03, Vol.5 (3), p.180-183

1998

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COOH-Terminal Truncations Promote Proteasome-Dependent Degradation of Mature Cystic Fibrosis Transmembrane Conductance Regulator from Post-Golgi Compartments

The Journal of cell biology, 2001-05, Vol.153 (5), p.957-970

2001

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Oligomerization State of the DNA Fragmentation Factor in Normal and Apoptotic Cells

The Journal of biological chemistry, 2005-12, Vol.280 (48), p.40216-40225

2005

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Constitutive internalization of cystic fibrosis transmembrane conductance regulator occurs via clathrin-dependent endocytosis and is regulated by protein phosphorylation

Biochemical journal, 1997-12, Vol.328 ( Pt 2) (2), p.353-361

1997

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Conformational maturation of CFTR but not its mutant counterpart (delta F508) occurs in the endoplasmic reticulum and requires ATP

The EMBO journal, 1994-12, Vol.13 (24), p.6076-6086

1994

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Contrasting Nuclear Dynamics of the Caspase-Activated DNase (CAD) in Dividing and Apoptotic Cells

The Journal of cell biology, 2004-12, Vol.167 (5), p.851-862

2004

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Destabilization of the Transmembrane Domain Induces Misfolding in a Phenotypic Mutant of Cystic Fibrosis Transmembrane Conductance Regulator

The Journal of biological chemistry, 2005-02, Vol.280 (6), p.4968-4974

2005

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A human epithelium-specific vector optimized in rat pneumocytes for lung gene therapy

Pediatric research, 2000-08, Vol.48 (2), p.184-190

2000

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The [Delta]F508 cystic fibrosis mutation impairs domain-domain interactions and arrests post-translational folding of CFTR

Nature structural & molecular biology, 2005-01, Vol.12 (1), p.17

2005

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Pharmacological and biochemical properties of saxiphilin, a soluble saxitoxin-binding protein from the bullfrog ( Rana catesbeiana)

Toxicon (Oxford), 1991, Vol.29 (1), p.53-71

1991

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Intracellular routing of plasmid DNA during non-viral gene transfer

Metabolic instability of plasmid DNA in the cytosol : a potential barrier to gene transfer

Nucleocytoplasmic transport of plasmid DNA: a perilous journey from the cytoplasm to the nucleus

C-terminal truncations destabilize the cystic fibrosis transmembrane conductance regulator without impairing its biogenesis. A novel class of mutation

The delta F508 mutation decreases the stability of cystic fibrosis transmembrane conductance regulator in the plasma membrane. Determination of functional half-lives on transfected cells

Curcumin, a Major Constituent of Turmeric, Corrects Cystic Fibrosis Defects

Intracellular barriers to non-viral gene transfer

Size-dependent DNA Mobility in Cytoplasm and Nucleus

Determinants of the Nuclear Localization of the Heterodimeric DNA Fragmentation Factor (ICAD/CAD)

Multiple endocytic signals in the C-terminal tail of the cystic fibrosis transmembrane conductance regulator

Phagosomal acidification is mediated by a vacuolar-type H(+)-ATPase in murine macrophages

Conformational and Temperature-sensitive Stability Defects of the ΔF508 Cystic Fibrosis Transmembrane Conductance Regulator in Post-endoplasmic Reticulum Compartments

Ubiquitin-dependent sorting in endocytosis

Proton conductance of the plasma membrane: properties, regulation, and functional role

The cystic fibrosis transmembrane regulator is present and functional in endosomes. Role as a determinant of endosomal pH

Limited proteolysis as a probe for arrested conformational maturation of ΔF508 CFTR

COOH-Terminal Truncations Promote Proteasome-Dependent Degradation of Mature Cystic Fibrosis Transmembrane Conductance Regulator from Post-Golgi Compartments

Oligomerization State of the DNA Fragmentation Factor in Normal and Apoptotic Cells

Constitutive internalization of cystic fibrosis transmembrane conductance regulator occurs via clathrin-dependent endocytosis and is regulated by protein phosphorylation

Conformational maturation of CFTR but not its mutant counterpart (delta F508) occurs in the endoplasmic reticulum and requires ATP

Contrasting Nuclear Dynamics of the Caspase-Activated DNase (CAD) in Dividing and Apoptotic Cells

Destabilization of the Transmembrane Domain Induces Misfolding in a Phenotypic Mutant of Cystic Fibrosis Transmembrane Conductance Regulator

A human epithelium-specific vector optimized in rat pneumocytes for lung gene therapy

The [Delta]F508 cystic fibrosis mutation impairs domain-domain interactions and arrests post-translational folding of CFTR

Pharmacological and biochemical properties of saxiphilin, a soluble saxitoxin-binding protein from the bullfrog ( Rana catesbeiana)

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