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A Hypothesis on the Origin and Evolution of Tubulin

International Review of Cell and Molecular Biology, 2013, Vol.302, p.41-185

Ludueña, Richard F.

2013

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Possible Roles of Specific Amino Acids in β-Tubulin Isotypes in the Growth and Maintenance of Neurons: Novel Insights From Cephalopod Mollusks

Frontiers in molecular neuroscience, 2022-04, Vol.15, p.838393-838393

Ludueña, Richard F

2022

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The taccalonolides: microtubule stabilizers that circumvent clinically relevant taxane resistance mechanisms

Cancer research (Chicago, Ill.), 2008-11, Vol.68 (21), p.8881-8888

2008

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Interactions of β tubulin isotypes with glutathione in differentiated neuroblastoma cells subject to oxidative stress

Cytoskeleton (Hoboken, N.J.), 2018-07, Vol.75 (7), p.283-289

2018

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Designing and Testing of Novel Taxanes to Probe the Highly Complex Mechanisms by Which Taxanes Bind to Microtubules and Cause Cytotoxicity to Cancer Cells

PloS one, 2015-06, Vol.10 (6), p.e0129168-e0129168

2015

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Identification and Characterization of an Intermediate Taxol Binding Site Within Microtubule Nanopores and a Mechanism for Tubulin Isotype Binding Selectivity

Journal of Chemical Information and Modeling, 2009-02, Vol.49 (2), p.424-436

2009

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The distribution of β-tubulin isotypes in cultured neurons from embryonic, newborn, and adult mouse brains

Brain research, 2011-10, Vol.1420, p.8-18

2011

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The β isotypes of tubulin in neuronal differentiation

Cytoskeleton (Hoboken, N.J.), 2010-07, Vol.67 (7), p.431-441

2010

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Nuclear βII-Tubulin and its Possible Utility in Cancer Diagnosis, Prognosis and Treatment

Frontiers in cell and developmental biology, 2022-05, Vol.10, p.870088-870088

2022

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Effect of CH-35, a novel anti-tumor colchicine analogue, on breast cancer cells overexpressing the βIII isotype of tubulin

Investigational new drugs, 2016-02, Vol.34 (1), p.129-137

2016

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Novel mutations involving βI-, βIIA-, or βIVB-tubulin isotypes with functional resemblance to βIII-tubulin in breast cancer

Protoplasma, 2017-05, Vol.254 (3), p.1163-1173

2017

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The G protein-coupled oestrogen receptor 1 agonist G-1 disrupts endothelial cell microtubule structure in a receptor-independent manner

Molecular and cellular biochemistry, 2012-07, Vol.366 (1-2), p.239-249

2012

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Microtubule Assembly of Isotypically Purified Tubulin and Its Mixtures

Biophysical journal, 2008-08, Vol.95 (4), p.1993-2008

2008

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Intracellular Activation and Deactivation of Tasidotin, an Analog of Dolastatin 15: Correlation with Cytotoxicity

Molecular pharmacology, 2009-01, Vol.75 (1), p.218-226

2009

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Structure of tubulin at 6.5 Å and location of the taxol-binding site

Nature (London), 1995-06, Vol.375 (6530), p.424-427

1995

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Direct involvement of the isotype-specific C-terminus of beta tubulin in ciliary beating

Journal of cell science, 2005-10, Vol.118 (Pt 19), p.4333-4341

2005

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Homology modeling of tubulin: influence predictions for microtubule's biophysical properties

European biophysics journal, 2006-12, Vol.36 (1), p.35-43

2006

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Differential expression of β tubulin isotypes in the adult gerbil cochlea

Hearing research, 2000-10, Vol.148 (1), p.161-172

2000

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Different effects of vinblastine on the polymerization of isotypically purified tubulins from bovine brain

Investigational new drugs, 2003-02, Vol.21 (1), p.3-13

2003

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Comparative modelling of human β tubulin isotypes and implications for drug binding

Nanotechnology, 2006-02, Vol.17 (4), p.S90-S100

2006

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Roles of β-Tubulin Residues Ala428 and Thr429 in Microtubule Formation in Vivo

The Journal of biological chemistry, 2009-02, Vol.284 (7), p.4283-4291

2009

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Microtubule Dynamics in vitro are Regulated by the Tubulin Isotype Composition

Proceedings of the National Academy of Sciences - PNAS, 1994-11, Vol.91 (24), p.11358-11362

1994

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Quantitative analysis of the effect of tubulin isotype expression on sensitivity of cancer cell lines to a set of novel colchicine derivatives

Molecular cancer, 2010-05, Vol.9 (1), p.131-131, Article 131

2010

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Taxol Differentially Modulates the Dynamics of Microtubules Assembled from Unfractionated and Purified β-Tubulin Isotypes

Biochemistry (Easton), 1997-03, Vol.36 (12), p.3554-3562

1997

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The evolution of the structure of tubulin and its potential consequences for the role and function of microtubules in cells and embryos

The International journal of developmental biology, 2006, Vol.50 (2-3), p.341

2006

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A Hypothesis on the Origin and Evolution of Tubulin

Possible Roles of Specific Amino Acids in β-Tubulin Isotypes in the Growth and Maintenance of Neurons: Novel Insights From Cephalopod Mollusks

The taccalonolides: microtubule stabilizers that circumvent clinically relevant taxane resistance mechanisms

Interactions of β tubulin isotypes with glutathione in differentiated neuroblastoma cells subject to oxidative stress

Designing and Testing of Novel Taxanes to Probe the Highly Complex Mechanisms by Which Taxanes Bind to Microtubules and Cause Cytotoxicity to Cancer Cells

Identification and Characterization of an Intermediate Taxol Binding Site Within Microtubule Nanopores and a Mechanism for Tubulin Isotype Binding Selectivity

The distribution of β-tubulin isotypes in cultured neurons from embryonic, newborn, and adult mouse brains

The β isotypes of tubulin in neuronal differentiation

Nuclear βII-Tubulin and its Possible Utility in Cancer Diagnosis, Prognosis and Treatment

Effect of CH-35, a novel anti-tumor colchicine analogue, on breast cancer cells overexpressing the βIII isotype of tubulin

Novel mutations involving βI-, βIIA-, or βIVB-tubulin isotypes with functional resemblance to βIII-tubulin in breast cancer

The G protein-coupled oestrogen receptor 1 agonist G-1 disrupts endothelial cell microtubule structure in a receptor-independent manner

Microtubule Assembly of Isotypically Purified Tubulin and Its Mixtures

Intracellular Activation and Deactivation of Tasidotin, an Analog of Dolastatin 15: Correlation with Cytotoxicity

Structure of tubulin at 6.5 Å and location of the taxol-binding site

Direct involvement of the isotype-specific C-terminus of beta tubulin in ciliary beating

Homology modeling of tubulin: influence predictions for microtubule's biophysical properties

Differential expression of β tubulin isotypes in the adult gerbil cochlea

Different effects of vinblastine on the polymerization of isotypically purified tubulins from bovine brain

Comparative modelling of human β tubulin isotypes and implications for drug binding

Roles of β-Tubulin Residues Ala428 and Thr429 in Microtubule Formation in Vivo

Microtubule Dynamics in vitro are Regulated by the Tubulin Isotype Composition

Quantitative analysis of the effect of tubulin isotype expression on sensitivity of cancer cell lines to a set of novel colchicine derivatives

Taxol Differentially Modulates the Dynamics of Microtubules Assembled from Unfractionated and Purified β-Tubulin Isotypes

The evolution of the structure of tubulin and its potential consequences for the role and function of microtubules in cells and embryos

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