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Short-term exposure of human ovarian follicles to cyclophosphamide metabolites seems to promote follicular activation in vitro

Reproductive biomedicine online, 2017-01, Vol.34 (1), p.104-114

2017

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Pharmacodynamic and pharmacokinetic study of chronic low-dose metronomic cyclophosphamide therapy in mice

Molecular cancer therapeutics, 2007-08, Vol.6 (8), p.2280-2289

2007

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Pharmacogenetic studies related to cyclophosphamide-based therapy

Pharmacogenomics, 2009-12, Vol.10 (12), p.1897

2009

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Evaluation of an elastin-like polypeptide–doxorubicin conjugate for cancer therapy

Journal of controlled release, 2003-08, Vol.91 (1), p.31-43

2003

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Isolation of Primitive Human Hematopoietic Progenitors on the Basis of Aldehyde Dehydrogenase Activity

Proceedings of the National Academy of Sciences - PNAS, 1999-08, Vol.96 (16), p.9118-9123

1999

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Synthesis of 13C-labeled derivatives of cysteine for magnetic resonance imaging studies of drug uptake and conversion to glutathione in rat brain

Journal of labelled compounds & radiopharmaceuticals, 2011-07, Vol.54 (9), p.607-612

2011

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Labeled oxazaphosphorines for applications in mass spectrometry studies. 2. Synthesis of deuterium-labeled 2-dechloroethylcyclophosphamides and 2- and 3-dechloroethylifosfamides

Journal of labelled compounds & radiopharmaceuticals, 2014-02, Vol.57 (2), p.110-114

2014

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Drug Focus: Pharmacogenetic studies related to cyclophosphamide-based therapy

Pharmacogenomics, 2009-12, Vol.10 (12), p.1897-1903

2009

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Role of MGMT in protecting against cyclophosphamide-induced toxicity in cells and animals

DNA repair, 2007-08, Vol.6 (8), p.1145-1154

2007

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Non-invasive Monitoring of L-2-Oxothiazolidine-4-Carboxylate Metabolism in the Rat Brain by In vivo 13C Magnetic Resonance Spectroscopy

Neurochemical research, 2011-03, Vol.36 (3), p.443-451

2011

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Labeled oxazaphosphorines for applications in MS studies. Synthesis of deuterium labeled cyclophosphamides and ifosfamides

Journal of labelled compounds & radiopharmaceuticals, 2007-02, Vol.50 (2), p.115-122

2007

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Synthesis of [3H,33P]-phosphoramide and -isophosphoramide mustards and metabolites [3H]-chloroethylaziridine and -aziridine for studies of DNA alkylation

Journal of labelled compounds & radiopharmaceuticals, 2007-02, Vol.50 (2), p.79-84

2007

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The chemistry of the metabolites of cyclophosphamide

Current pharmaceutical design, 1999-08, Vol.5 (8), p.627

Ludeman, S M

1999

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1,3- vs 1,5-Intramolecular Alkylation Reactions in Isophosphoramide and Phosphoramide Mustards

Chemical research in toxicology, 2004-09, Vol.17 (9), p.1217-1226

2004

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Integrating Cell-Based and Clinical Genome-Wide Studies to Identify Genetic Variants Contributing to Treatment Failure in Neuroblastoma Patients

Clinical pharmacology and therapeutics, 2014-06, Vol.95 (6), p.644-652

2014

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Isophosphoramide Mustard and Its Mechanism of Bisalkylation

Journal of organic chemistry, 1998-10, Vol.63 (21), p.7218-7222

1998

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A Structural Basis for a Phosphoramide Mustard-Induced DNA Interstrand Cross-Link at 5'-d(GAC)

Proceedings of the National Academy of Sciences - PNAS, 1995-12, Vol.92 (26), p.12170-12174

1995

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Modified guanines representing O(6)-alkylation by the cyclophosphamide metabolites acrolein and chloroacetaldehyde: synthesis, stability, and ab initio studies

Chemical research in toxicology, 2002-03, Vol.15 (3), p.380

2002

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Selective enhancement of ifosfamide-induced toxicity in Chinese hamster ovary cells

Cancer chemotherapy and pharmacology, 2003-10, Vol.52 (4), p.291-302

2003

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The Partitioning of Phosphoramide Mustard and Its Aziridinium Ions among Alkylation and P−N Bond Hydrolysis Reactions

Journal of medicinal chemistry, 1998-02, Vol.41 (4), p.515-529

1998

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Exposure to a Deuterated Analogue of Phenylbutyrate Retards S-Phase Progression in HT-29 Colon Cancer Cells

Journal of pharmaceutical sciences, 2002-04, Vol.91 (4), p.1054-1064

2002

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Mechanisms of resistance against cyclophosphamide and ifosfamide: can they be overcome without sacrificing selectivity?

Cancer treatment and research, 2002, Vol.112, p.177

2002

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Abstract 4766: The use of deuterium isotope effects to shift the partitioning of cyclophosphamide and ifosfamide among competing, P450-dependent, oxidative pathways

Cancer research (Chicago, Ill.), 2012-04, Vol.72 (8_Supplement), p.4766-4766

2012

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Modified Guanines Representing O 6-Alkylation by the Cyclophosphamide Metabolites Acrolein and Chloroacetaldehyde: Synthesis, Stability, and ab Initio Studies

Chemical research in toxicology, 2002-03, Vol.15 (3), p.380-387

2002

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Experimental chemotherapy of human medulloblastoma cell lines and transplantable xenografts with bifunctional alkylating agents

Cancer research (Chicago, Ill.), 1988-08, Vol.48 (15), p.4189-4195

1988

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Short-term exposure of human ovarian follicles to cyclophosphamide metabolites seems to promote follicular activation in vitro

Pharmacodynamic and pharmacokinetic study of chronic low-dose metronomic cyclophosphamide therapy in mice

Pharmacogenetic studies related to cyclophosphamide-based therapy

Evaluation of an elastin-like polypeptide–doxorubicin conjugate for cancer therapy

Isolation of Primitive Human Hematopoietic Progenitors on the Basis of Aldehyde Dehydrogenase Activity

Synthesis of 13C-labeled derivatives of cysteine for magnetic resonance imaging studies of drug uptake and conversion to glutathione in rat brain

Labeled oxazaphosphorines for applications in mass spectrometry studies. 2. Synthesis of deuterium-labeled 2-dechloroethylcyclophosphamides and 2- and 3-dechloroethylifosfamides

Drug Focus: Pharmacogenetic studies related to cyclophosphamide-based therapy

Role of MGMT in protecting against cyclophosphamide-induced toxicity in cells and animals

Non-invasive Monitoring of L-2-Oxothiazolidine-4-Carboxylate Metabolism in the Rat Brain by In vivo 13C Magnetic Resonance Spectroscopy

Labeled oxazaphosphorines for applications in MS studies. Synthesis of deuterium labeled cyclophosphamides and ifosfamides

Synthesis of [3H,33P]-phosphoramide and -isophosphoramide mustards and metabolites [3H]-chloroethylaziridine and -aziridine for studies of DNA alkylation

The chemistry of the metabolites of cyclophosphamide

1,3- vs 1,5-Intramolecular Alkylation Reactions in Isophosphoramide and Phosphoramide Mustards

Integrating Cell-Based and Clinical Genome-Wide Studies to Identify Genetic Variants Contributing to Treatment Failure in Neuroblastoma Patients

Isophosphoramide Mustard and Its Mechanism of Bisalkylation

A Structural Basis for a Phosphoramide Mustard-Induced DNA Interstrand Cross-Link at 5'-d(GAC)

Modified guanines representing O(6)-alkylation by the cyclophosphamide metabolites acrolein and chloroacetaldehyde: synthesis, stability, and ab initio studies

Selective enhancement of ifosfamide-induced toxicity in Chinese hamster ovary cells

The Partitioning of Phosphoramide Mustard and Its Aziridinium Ions among Alkylation and P−N Bond Hydrolysis Reactions

Exposure to a Deuterated Analogue of Phenylbutyrate Retards S-Phase Progression in HT-29 Colon Cancer Cells

Mechanisms of resistance against cyclophosphamide and ifosfamide: can they be overcome without sacrificing selectivity?

Abstract 4766: The use of deuterium isotope effects to shift the partitioning of cyclophosphamide and ifosfamide among competing, P450-dependent, oxidative pathways

Modified Guanines Representing O 6-Alkylation by the Cyclophosphamide Metabolites Acrolein and Chloroacetaldehyde: Synthesis, Stability, and ab Initio Studies

Experimental chemotherapy of human medulloblastoma cell lines and transplantable xenografts with bifunctional alkylating agents

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