UB Paderborn / Katalog / Suche / in CDI

Knockout or inhibition of USP30 protects dopaminergic neurons in a Parkinson's disease mouse model

Nature communications, 2023-11, Vol.14 (1), p.7295-7295, Article 7295

2023

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Evaluation of 5‑(Trifluoromethyl)-1,2,4-oxadiazole-Based Class IIa HDAC Inhibitors for Huntington’s Disease

ACS medicinal chemistry letters, 2021-03, Vol.12 (3), p.380-388

2021

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Potent, Selective, and CNS-Penetrant Tetrasubstituted Cyclopropane Class IIa Histone Deacetylase (HDAC) Inhibitors

ACS medicinal chemistry letters, 2016-01, Vol.7 (1), p.34-39

2016

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Identification of a Potent, Selective, and Brain-Penetrant Rho Kinase Inhibitor and its Activity in a Mouse Model of Huntington’s Disease

Journal of medicinal chemistry, 2022-07, Vol.65 (14), p.9819-9845

2022

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Development and characterization of a CNS-penetrant benzhydryl hydroxamic acid class IIa histone deacetylase inhibitor

Bioorganic & medicinal chemistry letters, 2019-01, Vol.29 (1), p.83-88

2019

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Discovery of isoindoline and tetrahydroisoquinoline derivatives as potent, selective PPARδ agonists

Bioorganic & medicinal chemistry letters, 2011-01, Vol.21 (1), p.492-496

2011

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Scaffold-hopping with zwitterionic CCR3 antagonists: Identification and optimisation of a series with good potency and pharmacokinetics leading to the discovery of AZ12436092

Bioorganic & medicinal chemistry letters, 2012-11, Vol.22 (21), p.6694-6699

2012

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Synthesis and biological evaluation of N-alkylated 8-oxybenz[c]azepine derivatives as selective PPARδ agonists

Bioorganic & medicinal chemistry letters, 2011-01, Vol.21 (1), p.531-536

2011

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The discovery of CCR3/H1 dual antagonists with reduced hERG risk

Bioorganic & medicinal chemistry letters, 2012-11, Vol.22 (21), p.6688-6693

2012

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A convenient synthesis of sulfonylureas from carboxylic acids and sulfonamides via an in situ Curtius rearrangement

Tetrahedron letters, 2007-12, Vol.48 (50), p.8878-8882

2007

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Abstract 454: Validation of GPR35 as a novel cancer target in digestive tract cancers and discovery of potent, selective GPR35 inverse agonists

Cancer research (Chicago, Ill.), 2023-04, Vol.83 (7_Supplement), p.454-454

2023

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ChemInform Abstract: A Convenient Synthesis of Sulfonylureas from Carboxylic Acids and Sulfonamides via an in situ Curtius Rearrangement

ChemInform, 2008-04, Vol.39 (15), p.no-no

2008

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Cathepsin C Inhibitors: Property Optimization and Identification of a Clinical Candidate

Journal of medicinal chemistry, 2014-03, Vol.57 (6), p.2357-2367

2014

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Geriatric Otolaryngology

1, 2015

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Renormalisation of general n=2 supersymmetric chern-simons theories in three dimensions

Luckhurst, Christopher

2013

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ProQuest

Discovery and evolution of phenoxypiperidine hydroxyamide dual CCR3/H1 antagonists. Part II: Optimising in vivo clearance

Bioorganic & medicinal chemistry letters, 2012-12, Vol.22 (24), p.7707-7710

2012

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Discovery and evolution of phenoxypiperidine hydroxyamide dual CCR3/H1 antagonists. Part I

Bioorganic & medicinal chemistry letters, 2012-12, Vol.22 (24), p.7702-7706

2012

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A study of the director distribution using deuterium NMR spectroscopy and simultaneous in situ observation of the light transmittance for a nematic subject to magnetic, electric and surface fields

Current applied physics, 2006-09, Vol.6 (5), p.891-896

2006

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A study of the director distribution using deuterium NMR spectroscopy and simultaneous in situ observation of the light transmittance for a nematic subject to magnetic, electric and surface fields

Current Applied Physics, 2006, 6(5), , pp.891-896

2006

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British drama of the 1990s

2002

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Unlocking Synge Today

A Companion to Modern British and Irish Drama 1880–2005, 2006, p.110-124

2006

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Studies towards the total synthesis of the phorboxazoles

Luckhurst, Christopher Andrew

2002

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Knockout or inhibition of USP30 protects dopaminergic neurons in a Parkinson's disease mouse model

Design, Synthesis, and Biological Evaluation of Potent and Selective Class IIa Histone Deacetylase (HDAC) Inhibitors as a Potential Therapy for Huntington’s Disease

Evaluation of 5‑(Trifluoromethyl)-1,2,4-oxadiazole-Based Class IIa HDAC Inhibitors for Huntington’s Disease

Potent, Selective, and CNS-Penetrant Tetrasubstituted Cyclopropane Class IIa Histone Deacetylase (HDAC) Inhibitors

Identification of a Potent, Selective, and Brain-Penetrant Rho Kinase Inhibitor and its Activity in a Mouse Model of Huntington’s Disease

Development and characterization of a CNS-penetrant benzhydryl hydroxamic acid class IIa histone deacetylase inhibitor

Discovery of isoindoline and tetrahydroisoquinoline derivatives as potent, selective PPARδ agonists

Scaffold-hopping with zwitterionic CCR3 antagonists: Identification and optimisation of a series with good potency and pharmacokinetics leading to the discovery of AZ12436092

Synthesis and biological evaluation of N-alkylated 8-oxybenz[c]azepine derivatives as selective PPARδ agonists

The discovery of CCR3/H1 dual antagonists with reduced hERG risk

A convenient synthesis of sulfonylureas from carboxylic acids and sulfonamides via an in situ Curtius rearrangement

Abstract 454: Validation of GPR35 as a novel cancer target in digestive tract cancers and discovery of potent, selective GPR35 inverse agonists

ChemInform Abstract: A Convenient Synthesis of Sulfonylureas from Carboxylic Acids and Sulfonamides via an in situ Curtius Rearrangement

Home and Online Management and Evaluation of Blood Pressure (HOME BP) using a digital intervention in poorly controlled hypertension: randomised controlled trial

Cathepsin C Inhibitors: Property Optimization and Identification of a Clinical Candidate

Geriatric Otolaryngology

Renormalisation of general n=2 supersymmetric chern-simons theories in three dimensions

Discovery and evolution of phenoxypiperidine hydroxyamide dual CCR3/H1 antagonists. Part II: Optimising in vivo clearance

Discovery and evolution of phenoxypiperidine hydroxyamide dual CCR3/H1 antagonists. Part I

Geriatric Otolaryngology

A study of the director distribution using deuterium NMR spectroscopy and simultaneous in situ observation of the light transmittance for a nematic subject to magnetic, electric and surface fields

A study of the director distribution using deuterium NMR spectroscopy and simultaneous in situ observation of the light transmittance for a nematic subject to magnetic, electric and surface fields

British drama of the 1990s

Unlocking Synge Today

Studies towards the total synthesis of the phorboxazoles

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