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A pipeline for multidimensional confocal analysis of mitochondrial morphology, function, and dynamics in pancreatic β-cells

American journal of physiology: endocrinology and metabolism, 2020-02, Vol.318 (2), p.E87-E101

2020

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Alloantigen-specific regulatory T cells generated with a chimeric antigen receptor

The Journal of clinical investigation, 2016-04, Vol.126 (4), p.1413-1424

2016

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Complex Patterns of Metabolic and Ca2+ Entrainment in Pancreatic Islets by Oscillatory Glucose

Biophysical journal, 2013-07, Vol.105 (1), p.29-39

2013

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41-OR: Roles of Transcription Factor EB (TFEB) in ß-Cell Function and Survival Under Stress

Diabetes (New York, N.Y.), 2021-06, Vol.70 (Supplement_1), p.287

2021

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Transcriptional coactivator MED15 is required for beta cell maturation

Nature communications, 2024-10, Vol.15 (1), p.8711-15, Article 8711

2024

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Methylation of histone H3 lysine 4 is required for maintenance of beta cell function in adult mice

Diabetologia, 2023-06, Vol.66 (6), p.1097-1115

2023

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123-OR: Deletion of Both Pcsk1 And Pcsk2 in Beta Cells: Lack of Mature Insulin Drives Beta-Cell Expansion and Dysfunction, but Not Severe Diabetes in Mice

Diabetes (New York, N.Y.), 2021-06, Vol.70 (Supplement_1)

2021

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Cellular metabolism constrains innate immune responses in early human ontogeny

Nature communications, 2018-11, Vol.9 (1), p.4822-12, Article 4822

2018

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The role of mitochondrial apoptotic pathway in islet amyloid-induced β-cell death

Molecular and cellular endocrinology, 2021-11, Vol.537, p.111424, Article 111424

2021

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Cardiomyocyte ATP Production, Metabolic Flexibility, and Survival Require Calcium Flux through Cardiac Ryanodine Receptors in Vivo

The Journal of biological chemistry, 2013-06, Vol.288 (26), p.18975-18986

2013

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The p300 and CBP Transcriptional Coactivators Are Required for β-Cell and α-Cell Proliferation

Diabetes (New York, N.Y.), 2018-03, Vol.67 (3), p.412-422

2018

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Roles of IP3R and RyR Ca2+ Channels in Endoplasmic Reticulum Stress and β-Cell Death

Diabetes (New York, N.Y.), 2009-02, Vol.58 (2), p.422-432

2009

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Bax and Bak jointly control survival and dampen the early unfolded protein response in pancreatic β-cells under glucolipotoxic stress

Scientific reports, 2020-07, Vol.10 (1), p.10986, Article 10986

2020

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Bcl-2 Regulates Reactive Oxygen Species Signaling and a Redox-Sensitive Mitochondrial Proton Leak in Mouse Pancreatic β-Cells

Endocrinology (Philadelphia), 2016-06, Vol.157 (6), p.2270-2281

2016

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Carboxypeptidase E mediates palmitate-induced β-cell ER stress and apoptosis

Proceedings of the National Academy of Sciences - PNAS, 2008-06, Vol.105 (24), p.8452-8457

2008

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A simplified model for mitochondrial ATP production

Journal of theoretical biology, 2006-12, Vol.243 (4), p.575-586

2006

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Increased islet apoptosis in Pdx1+/- mice

The Journal of clinical investigation, 2003-04, Vol.111 (8), p.1147-1160

2003

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Type 2 diabetes susceptibility gene GRK5 regulates physiological pancreatic β-cell proliferation via phosphorylation of HDAC5

iScience, 2023-08, Vol.26 (8), p.107311-107311, Article 107311

2023

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Ca2+ controls slow NAD(P)H oscillations in glucose-stimulated mouse pancreatic islets

The Journal of physiology, 2006-04, Vol.572 (2), p.379-392

2006

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Maturation of Adult β-Cells Revealed Using a Pdx1/Insulin Dual-Reporter Lentivirus

Endocrinology (Philadelphia), 2009-04, Vol.150 (4), p.1627-1635

2009

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Interaction of Glycolysis and Mitochondrial Respiration in Metabolic Oscillations of Pancreatic Islets

Biophysical journal, 2007-03, Vol.92 (5), p.1544-1555

2007

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MISC-1/OGC links mitochondrial metabolism, apoptosis and insulin secretion

PloS one, 2011-03, Vol.6 (3), p.e17827-e17827

2011

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Bcl-2 and Bcl-xL Suppress Glucose Signaling in Pancreatic β-Cells

Diabetes (New York, N.Y.), 2013-01, Vol.62 (1), p.170-182

2013

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Control of Insulin Secretion by Cytochrome c and Calcium Signaling in Islets with Impaired Metabolism

The Journal of biological chemistry, 2014-07, Vol.289 (27), p.19110-19119

2014

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AMP-activated protein kinase confers protection against TNF-α-induced cardiac cell death

Cardiovascular research, 2009-10, Vol.84 (1), p.42-53

2009

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A pipeline for multidimensional confocal analysis of mitochondrial morphology, function, and dynamics in pancreatic β-cells

Alloantigen-specific regulatory T cells generated with a chimeric antigen receptor

Complex Patterns of Metabolic and Ca2+ Entrainment in Pancreatic Islets by Oscillatory Glucose

41-OR: Roles of Transcription Factor EB (TFEB) in ß-Cell Function and Survival Under Stress

Transcriptional coactivator MED15 is required for beta cell maturation

Methylation of histone H3 lysine 4 is required for maintenance of beta cell function in adult mice

123-OR: Deletion of Both Pcsk1 And Pcsk2 in Beta Cells: Lack of Mature Insulin Drives Beta-Cell Expansion and Dysfunction, but Not Severe Diabetes in Mice

Cellular metabolism constrains innate immune responses in early human ontogeny

The role of mitochondrial apoptotic pathway in islet amyloid-induced β-cell death

Cardiomyocyte ATP Production, Metabolic Flexibility, and Survival Require Calcium Flux through Cardiac Ryanodine Receptors in Vivo

The p300 and CBP Transcriptional Coactivators Are Required for β-Cell and α-Cell Proliferation

Roles of IP3R and RyR Ca2+ Channels in Endoplasmic Reticulum Stress and β-Cell Death

Bax and Bak jointly control survival and dampen the early unfolded protein response in pancreatic β-cells under glucolipotoxic stress

Bcl-2 Regulates Reactive Oxygen Species Signaling and a Redox-Sensitive Mitochondrial Proton Leak in Mouse Pancreatic β-Cells

Carboxypeptidase E mediates palmitate-induced β-cell ER stress and apoptosis

A simplified model for mitochondrial ATP production

Increased islet apoptosis in Pdx1+/- mice

Type 2 diabetes susceptibility gene GRK5 regulates physiological pancreatic β-cell proliferation via phosphorylation of HDAC5

Ca2+ controls slow NAD(P)H oscillations in glucose-stimulated mouse pancreatic islets

Maturation of Adult β-Cells Revealed Using a Pdx1/Insulin Dual-Reporter Lentivirus

Interaction of Glycolysis and Mitochondrial Respiration in Metabolic Oscillations of Pancreatic Islets

MISC-1/OGC links mitochondrial metabolism, apoptosis and insulin secretion

Bcl-2 and Bcl-xL Suppress Glucose Signaling in Pancreatic β-Cells

Control of Insulin Secretion by Cytochrome c and Calcium Signaling in Islets with Impaired Metabolism

AMP-activated protein kinase confers protection against TNF-α-induced cardiac cell death

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