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Estimating human ADME properties, pharmacokinetic parameters and likely clinical dose in drug discovery

Expert opinion on drug discovery, 2019-12, Vol.14 (12), p.1313-1327

2019

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Evaluation of area under the concentration curve adjusted by the terminal‐phase as a metric to reduce the impact of variability in bioequivalence testing

British journal of clinical pharmacology, 2022-02, Vol.88 (2), p.619-627

2022

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The relationship between school ground design and intensity of physical activity

Children's geographies, 2009-08, Vol.7 (3), p.261-276

2009

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Where do children choose to play on the school ground? The influence of green design

Education 3-13, 2010-05, Vol.38 (2), p.177-189

2010

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2′ Biaryl amides as novel and subtype selective M1 agonists. Part II: Further optimization and profiling

Bioorganic & medicinal chemistry letters, 2010-06, Vol.20 (12), p.3545-3549

2010

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The discovery of a series of N-substituted 3-(4-piperidinyl)-1,3-benzoxazolinones and oxindoles as highly brain penetrant, selective muscarinic M1 agonists

Bioorganic & medicinal chemistry letters, 2010-09, Vol.20 (18), p.5434-5438

2010

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The discovery of a series of N-substituted 3-(4-piperidinyl)-1,3-benzoxazolinones and oxindoles as highly brain penetrant, selective muscarinic M 1 agonists

Bioorganic & medicinal chemistry letters, 2010-09, Vol.20 (18), p.5434-5438

2010

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The discovery of an orally efficacious positive allosteric modulator of the calcium sensing receptor containing a dibenzylamine core

Bioorganic & medicinal chemistry letters, 2010-09, Vol.20 (18), p.5544-5547

2010

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The discovery of a series of N-substituted 3-(4-piperidinyl)-1,3-benzoxazolinones and oxindoles as highly brain penetrant, selective muscarinic M sub(1) agonists

Bioorganic & medicinal chemistry letters, 2010-09, Vol.20 (18), p.5434-5438

2010

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A 2.4% DETERMINATION OF THE LOCAL VALUE OF THE HUBBLE CONSTANT

The Astrophysical journal, 2016-07, Vol.826 (1), p.56-56

2016

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Miscarriage matters: the epidemiological, physical, psychological, and economic costs of early pregnancy loss

The Lancet (British edition), 2021-05, Vol.397 (10285), p.1658-1667

2021

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Disentangling Self-Concept Clarity and Self-Esteem in Young Adults

Journal of personality and social psychology, 2023-12, Vol.125 (6), p.1420-1441

2023

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Milky Way Cepheid Standards for Measuring Cosmic Distances and Application to Gaia DR2: Implications for the Hubble Constant

The Astrophysical journal, 2018-07, Vol.861 (2), p.126

2018

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The RSNA Pediatric Bone Age Machine Learning Challenge

Radiology, 2019-02, Vol.290 (2), p.498

2019

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New Parallaxes of Galactic Cepheids from Spatially Scanning the Hubble Space Telescope: Implications for the Hubble Constant

The Astrophysical journal, 2018-03, Vol.855 (2), p.136

2018

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Metagenomic analysis reveals global-scale patterns of ocean nutrient limitation

Science (American Association for the Advancement of Science), 2021-04, Vol.372 (6539), p.287-291

2021

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Culture of primary ciliary dyskinesia epithelial cells at air-liquid interface can alter ciliary phenotype but remains a robust and informative diagnostic aid

PloS one, 2014-02, Vol.9 (2), p.e89675-e89675

2014

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Catching the Killer: Dynamic Disorder Design Rules for Small‐Molecule Organic Semiconductors

Advanced functional materials, 2023-04, Vol.33 (14), p.n/a

2023

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Maternal periconceptional and gestational low protein diet affects mouse offspring growth, cardiovascular and adipose phenotype at 1 year of age

PloS one, 2011-12, Vol.6 (12), p.e28745

2011

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THREE WIDE PLANETARY-MASS COMPANIONS TO FW TAU, ROXs 12, AND ROXs 42B

The Astrophysical journal, 2014-01, Vol.781 (1), p.1-16

2014

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Prediction of protein-ligand binding affinity from sequencing data with interpretable machine learning

Nature biotechnology, 2022-10, Vol.40 (10), p.1520-1527

2022

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Cognitive Vulnerability: An Epistemological Approach

González-Castán, Óscar Lucas

1, 2023

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Combined multidimensional single-cell protein and RNA profiling dissects the cellular and functional heterogeneity of thymic epithelial cells

Nature communications, 2023-07, Vol.14 (1), p.4071-4071, Article 4071

2023

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Safeguarding pollinators and their values to human well-being

Nature (London), 2016-12, Vol.540 (7632), p.220-229

2016

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Estimating human ADME properties, pharmacokinetic parameters and likely clinical dose in drug discovery

Evaluation of area under the concentration curve adjusted by the terminal‐phase as a metric to reduce the impact of variability in bioequivalence testing

The relationship between school ground design and intensity of physical activity

Where do children choose to play on the school ground? The influence of green design

2′ Biaryl amides as novel and subtype selective M1 agonists. Part II: Further optimization and profiling

The discovery of a series of N-substituted 3-(4-piperidinyl)-1,3-benzoxazolinones and oxindoles as highly brain penetrant, selective muscarinic M1 agonists

The discovery of a series of N-substituted 3-(4-piperidinyl)-1,3-benzoxazolinones and oxindoles as highly brain penetrant, selective muscarinic M 1 agonists

The discovery of an orally efficacious positive allosteric modulator of the calcium sensing receptor containing a dibenzylamine core

The discovery of a series of N-substituted 3-(4-piperidinyl)-1,3-benzoxazolinones and oxindoles as highly brain penetrant, selective muscarinic M sub(1) agonists

A 2.4% DETERMINATION OF THE LOCAL VALUE OF THE HUBBLE CONSTANT

Miscarriage matters: the epidemiological, physical, psychological, and economic costs of early pregnancy loss

A Single-Dose Intranasal ChAd Vaccine Protects Upper and Lower Respiratory Tracts against SARS-CoV-2

Disentangling Self-Concept Clarity and Self-Esteem in Young Adults

Milky Way Cepheid Standards for Measuring Cosmic Distances and Application to Gaia DR2: Implications for the Hubble Constant

The RSNA Pediatric Bone Age Machine Learning Challenge

New Parallaxes of Galactic Cepheids from Spatially Scanning the Hubble Space Telescope: Implications for the Hubble Constant

Metagenomic analysis reveals global-scale patterns of ocean nutrient limitation

Culture of primary ciliary dyskinesia epithelial cells at air-liquid interface can alter ciliary phenotype but remains a robust and informative diagnostic aid

Catching the Killer: Dynamic Disorder Design Rules for Small‐Molecule Organic Semiconductors

Maternal periconceptional and gestational low protein diet affects mouse offspring growth, cardiovascular and adipose phenotype at 1 year of age

THREE WIDE PLANETARY-MASS COMPANIONS TO FW TAU, ROXs 12, AND ROXs 42B

Prediction of protein-ligand binding affinity from sequencing data with interpretable machine learning

Cognitive Vulnerability: An Epistemological Approach

Combined multidimensional single-cell protein and RNA profiling dissects the cellular and functional heterogeneity of thymic epithelial cells

Safeguarding pollinators and their values to human well-being

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