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Deficiency of ganglioside GM1 correlates with Parkinson's disease in mice and humans

Journal of neuroscience research, 2012-10, Vol.90 (10), p.1997-2008

2012

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Systemic deficiency of GM1 ganglioside in Parkinson’s disease tissues and its relation to the disease etiology

Glycoconjugate journal, 2022-02, Vol.39 (1), p.75-82

2022

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Functional interplay between ganglioside GM1 and cross‐linking galectin‐1 induces axon‐like neuritogenesis via integrin‐based signaling and TRPC5‐dependent Ca2+ influx

Journal of neurochemistry, 2016-02, Vol.136 (3), p.550-563

2016

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Mice Lacking Major Brain Gangliosides Develop Parkinsonism

Neurochemical research, 2011-09, Vol.36 (9), p.1706-1714

2011

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Age-Related Decline in Gangliosides GM1 and GD1a in Non-CNS Tissues of Normal Mice: Implications for Peripheral Symptoms of Parkinson's Disease

Biomedicines, 2023-01, Vol.11 (1), p.209

2023

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Sodium-calcium exchanger complexed with GM1 ganglioside in nuclear membrane transfers calcium from nucleoplasm to endoplasmic reticulum

Proceedings of the National Academy of Sciences - PNAS, 2009-06, Vol.106 (26), p.10829-10834

2009

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Mice deficient in GM1 manifest both motor and non-motor symptoms of Parkinson's disease; successful treatment with synthetic GM1 ganglioside

Experimental neurology, 2020-07, Vol.329, p.113284-113284, Article 113284

2020

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Sialidase occurs in both membranes of the nuclear envelope and hydrolyzes endogenous GD1a

Journal of neurochemistry, 2009-10, Vol.111 (2), p.547-554

2009

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Cross-Linking of GM1 Ganglioside by Galectin-1 Mediates Regulatory T Cell Activity Involving TRPC5 Channel Activation: Possible Role in Suppressing Experimental Autoimmune Encephalomyelitis

The Journal of immunology (1950), 2009-04, Vol.182 (7), p.4036-4045

2009

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GDNF signaling implemented by GM1 ganglioside; failure in Parkinson's disease and GM1-deficient murine model

Experimental neurology, 2015-01, Vol.263, p.177-189

2015

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Ganglioside GM1 Deficiency in Effector T Cells From NOD Mice Induces Resistance to Regulatory T-Cell Suppression

Diabetes (New York, N.Y.), 2011-09, Vol.60 (9), p.2341-2349

2011

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Induction of Calcium Influx through TRPC5 Channels by Cross-Linking of GM1 Ganglioside Associated with α5β1 Integrin Initiates Neurite Outgrowth

The Journal of neuroscience, 2007-07, Vol.27 (28), p.7447-7458

2007

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Bimodal occurrence of aspartoacylase in myelin and cytosol of brain

Journal of neurochemistry, 2007-04, Vol.101 (2), p.448-457

2007

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The Role of GM1 and Other Gangliosides in Neuronal Differentiation Overview and New Findings

Annals of the New York Academy of Sciences, 1998-06, Vol.845 (1), p.161-175

1998

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Potentiation of a sodium–calcium exchanger in the nuclear envelope by nuclear GM1 ganglioside

Journal of neurochemistry, 2002-06, Vol.81 (6), p.1185-1195

2002

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Cerebellar Neurons Lacking Complex Gangliosides Degenerate in the Presence of Depolarizing Levels of Potassium

Proceedings of the National Academy of Sciences - PNAS, 2001-01, Vol.98 (1), p.307-312

2001

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Presence of sodium-calcium exchanger/GM1 complex in the nuclear envelope of non-neural cells: nature of exchanger-GM1 interaction

Neurochemical research, 2004-11, Vol.29 (11), p.2135-2146

2004

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Enhanced Susceptibility to Kainate-Induced Seizures, Neuronal Apoptosis, and Death in Mice Lacking Gangliotetraose Gangliosides: Protection with LIGA 20, a Membrane-Permeant Analog of GM1

The Journal of neuroscience, 2005-11, Vol.25 (47), p.11014-11022

2005

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N-Acetylaspartate synthase is bimodally expressed in microsomes and mitochondria of brain

Brain research. Molecular brain research., 2004-03, Vol.122 (1), p.71-78

2004

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Mutant NG108‐15 cells (NG‐CR72) deficient in GM1 synthase respond aberrantly to axonogenic stimuli and are vulnerable to calcium‐induced apoptosis: they are rescued with LIGA‐20

Journal of neurochemistry, 2001-02, Vol.76 (3), p.690-702

2001

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GM1 Ganglioside in the Nuclear Membrane Modulates Nuclear Calcium Homeostasis During Neurite Outgrowth

Journal of neurochemistry, 1995-09, Vol.65 (3), p.1419-1422

1995

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Susceptibility of cerebellar granule neurons from GM2/GD2 synthase-null mice to apoptosis induced by glutamate excitotoxicity and elevated KCl: rescue by GM1 and LIGA20

Glycoconjugate journal, 2004-01, Vol.21 (6), p.305-313

2004

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Gangliosides Stimulate Calcium Flux in Neuro‐2A Cells and Require Exogenous Calcium for Neuritogenesis

Journal of neurochemistry, 1990-08, Vol.55 (2), p.484-491

1990

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Physiological Role of N-Acetylaspartate: Contribution to Myelinogenesis

Advances in experimental medicine and biology, 2006, Vol.576, p.131-143

2006

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Functional interplay between ganglioside GM1 and cross-linking galectin-1 induces axon-like neuritogenesis via integrin-based signaling and TRPC5-dependent Ca super(2+) influx

Journal of neurochemistry, 2016-02, Vol.136 (3), p.550-563

2016

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Deficiency of ganglioside GM1 correlates with Parkinson's disease in mice and humans

Systemic deficiency of GM1 ganglioside in Parkinson’s disease tissues and its relation to the disease etiology

Functional interplay between ganglioside GM1 and cross‐linking galectin‐1 induces axon‐like neuritogenesis via integrin‐based signaling and TRPC5‐dependent Ca2+ influx

Mice Lacking Major Brain Gangliosides Develop Parkinsonism

Age-Related Decline in Gangliosides GM1 and GD1a in Non-CNS Tissues of Normal Mice: Implications for Peripheral Symptoms of Parkinson's Disease

Sodium-calcium exchanger complexed with GM1 ganglioside in nuclear membrane transfers calcium from nucleoplasm to endoplasmic reticulum

Mice deficient in GM1 manifest both motor and non-motor symptoms of Parkinson's disease; successful treatment with synthetic GM1 ganglioside

Sialidase occurs in both membranes of the nuclear envelope and hydrolyzes endogenous GD1a

Cross-Linking of GM1 Ganglioside by Galectin-1 Mediates Regulatory T Cell Activity Involving TRPC5 Channel Activation: Possible Role in Suppressing Experimental Autoimmune Encephalomyelitis

GDNF signaling implemented by GM1 ganglioside; failure in Parkinson's disease and GM1-deficient murine model

Ganglioside GM1 Deficiency in Effector T Cells From NOD Mice Induces Resistance to Regulatory T-Cell Suppression

Induction of Calcium Influx through TRPC5 Channels by Cross-Linking of GM1 Ganglioside Associated with α5β1 Integrin Initiates Neurite Outgrowth

Bimodal occurrence of aspartoacylase in myelin and cytosol of brain

The Role of GM1 and Other Gangliosides in Neuronal Differentiation Overview and New Findings

Potentiation of a sodium–calcium exchanger in the nuclear envelope by nuclear GM1 ganglioside

Cerebellar Neurons Lacking Complex Gangliosides Degenerate in the Presence of Depolarizing Levels of Potassium

Presence of sodium-calcium exchanger/GM1 complex in the nuclear envelope of non-neural cells: nature of exchanger-GM1 interaction

Enhanced Susceptibility to Kainate-Induced Seizures, Neuronal Apoptosis, and Death in Mice Lacking Gangliotetraose Gangliosides: Protection with LIGA 20, a Membrane-Permeant Analog of GM1

N-Acetylaspartate synthase is bimodally expressed in microsomes and mitochondria of brain

Mutant NG108‐15 cells (NG‐CR72) deficient in GM1 synthase respond aberrantly to axonogenic stimuli and are vulnerable to calcium‐induced apoptosis: they are rescued with LIGA‐20

GM1 Ganglioside in the Nuclear Membrane Modulates Nuclear Calcium Homeostasis During Neurite Outgrowth

Susceptibility of cerebellar granule neurons from GM2/GD2 synthase-null mice to apoptosis induced by glutamate excitotoxicity and elevated KCl: rescue by GM1 and LIGA20

Gangliosides Stimulate Calcium Flux in Neuro‐2A Cells and Require Exogenous Calcium for Neuritogenesis

Physiological Role of N-Acetylaspartate: Contribution to Myelinogenesis

Functional interplay between ganglioside GM1 and cross-linking galectin-1 induces axon-like neuritogenesis via integrin-based signaling and TRPC5-dependent Ca super(2+) influx

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