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Targeting Pyrimidine Metabolism in the Era of Precision Cancer Medicine

Frontiers in oncology, 2021-05, Vol.11, p.684961-684961

2021

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Target identification among known drugs by deep learning from heterogeneous networks

Chemical science (Cambridge), 2020-01, Vol.11 (7), p.1775-1797

2020

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Prediction of drug-target interactions and drug repositioning via network-based inference

PLoS computational biology, 2012-05, Vol.8 (5), p.e1002503

2012

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A genome-wide positioning systems network algorithm for in silico drug repurposing

Nature communications, 2019-08, Vol.10 (1), p.3476-14, Article 3476

2019

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Research on rotor fault diagnosis technology of three-phase asynchronous motor based on NA-MEMD mutual information and SVM

Measurement and control (London), 2024-05

2024

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Suppression of KRas-mutant cancer through the combined inhibition of KRAS with PLK1 and ROCK

Nature communications, 2016-05, Vol.7 (1), p.11363-13, Article 11363

2016

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METTL3 promotes non-small cell lung cancer (NSCLC) cell proliferation and colony formation in a m6A-YTHDF1 dependent way

BMC pulmonary medicine, 2022-08, Vol.22 (1), p.1-324, Article 324

2022

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Individualized genetic network analysis reveals new therapeutic vulnerabilities in 6,700 cancer genomes

PLoS computational biology, 2020-02, Vol.16 (2), p.e1007701

2020

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Pharmacological inhibition of dihydroorotate dehydrogenase induces apoptosis and differentiation in acute myeloid leukemia cells

Haematologica (Roma), 2018-09, Vol.103 (9), p.1472-1483

2018

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Shape Characteristic Analysis of Chaotic Attractors for Leakage Current Signal of Ice-Covered Insulator

IEEE access, 2021, Vol.9, p.125768-125777

2021

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Highly CO2/N2‑Switchable Zwitterionic Surfactant for Pickering Emulsions at Ambient Temperature

Langmuir, 2014-09, Vol.30 (34), p.10248-10255

2014

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Reprogramming immunosuppressive myeloid cells facilitates immunotherapy for colorectal cancer

EMBO molecular medicine, 2021-01, Vol.13 (1), p.e12798-n/a

2021

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PPIA dictates NRF2 stability to promote lung cancer progression

Nature communications, 2024-06, Vol.15 (1), p.4703-20

2024

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Discovery and Characterization of 1H‑1,2,3-Triazole Derivatives as Novel Prostanoid EP4 Receptor Antagonists for Cancer Immunotherapy

Journal of medicinal chemistry, 2020-01, Vol.63 (2), p.569-590

2020

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Correction: METTL3 promotes non-small cell lung cancer (NSCLC) cell proliferation and colony formation in a m6A-YTHDF1 dependent way

BMC pulmonary medicine, 2022-11, Vol.22 (1), p.1-450, Article 450

2022

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A Novel Small Molecular Prostaglandin Receptor EP4 Antagonist, L001, Suppresses Pancreatic Cancer Metastasis

Molecules (Basel, Switzerland), 2022-02, Vol.27 (4), p.1209

2022

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PGE2 activates EP4 in subchondral bone osteoclasts to regulate osteoarthritis

Bone Research, 2022-03, Vol.10 (1), p.27-27, Article 27

2022

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Moracin C, A Phenolic Compound Isolated from Artocarpus heterophyllus, Suppresses Lipopolysaccharide-Activated Inflammatory Responses in Murine Raw264.7 Macrophages

International journal of molecular sciences, 2016-07, Vol.17 (8), p.1199-1199

2016

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Research on Intelligent Crack Detection in a Deep-Cut Canal Slope in the Chinese South–North Water Transfer Project

Remote sensing (Basel, Switzerland), 2022-11, Vol.14 (21), p.5384

2022

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Structure-Based Discovery of a Subtype-Selective Inhibitor Targeting a Transient Receptor Potential Vanilloid Channel

Journal of medicinal chemistry, 2019-02, Vol.62 (3), p.1373-1384

2019

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Coptisine, a natural alkaloid from Coptidis Rhizoma, inhibits plasmodium falciparum dihydroorotate dehydrogenase

Chemical biology & drug design, 2018-07, Vol.92 (1), p.1324-1332

2018

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Activation of orphan receptor GPR132 induces cell differentiation in acute myeloid leukemia

Cell death & disease, 2022-11, Vol.13 (11), p.1004-1004, Article 1004

2022

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Inhibiting cytoplasmic accumulation of HuR synergizes genotoxic agents in urothelial carcinoma of the bladder

Oncotarget, 2016-07, Vol.7 (29), p.45249-45262

2016

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Selective activation of TWIK-related acid-sensitive K + 3 subunit–containing channels is analgesic in rodent models

Science translational medicine, 2019-11, Vol.11 (519)

2019

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Research on Soil Moisture Inversion Method for Canal Slope of the Middle Route Project of the South to North Water Transfer Based on GNSS-R and Deep Learning

Remote sensing (Basel, Switzerland), 2023-09, Vol.15 (17), p.4340

2023

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Targeting Pyrimidine Metabolism in the Era of Precision Cancer Medicine

Target identification among known drugs by deep learning from heterogeneous networks

Prediction of drug-target interactions and drug repositioning via network-based inference

A genome-wide positioning systems network algorithm for in silico drug repurposing

Research on rotor fault diagnosis technology of three-phase asynchronous motor based on NA-MEMD mutual information and SVM

Suppression of KRas-mutant cancer through the combined inhibition of KRAS with PLK1 and ROCK

METTL3 promotes non-small cell lung cancer (NSCLC) cell proliferation and colony formation in a m6A-YTHDF1 dependent way

Individualized genetic network analysis reveals new therapeutic vulnerabilities in 6,700 cancer genomes

Pharmacological inhibition of dihydroorotate dehydrogenase induces apoptosis and differentiation in acute myeloid leukemia cells

Shape Characteristic Analysis of Chaotic Attractors for Leakage Current Signal of Ice-Covered Insulator

Highly CO2/N2‑Switchable Zwitterionic Surfactant for Pickering Emulsions at Ambient Temperature

Reprogramming immunosuppressive myeloid cells facilitates immunotherapy for colorectal cancer

PPIA dictates NRF2 stability to promote lung cancer progression

Discovery and Characterization of 1H‑1,2,3-Triazole Derivatives as Novel Prostanoid EP4 Receptor Antagonists for Cancer Immunotherapy

Correction: METTL3 promotes non-small cell lung cancer (NSCLC) cell proliferation and colony formation in a m6A-YTHDF1 dependent way

A Novel Small Molecular Prostaglandin Receptor EP4 Antagonist, L001, Suppresses Pancreatic Cancer Metastasis

PGE2 activates EP4 in subchondral bone osteoclasts to regulate osteoarthritis

Moracin C, A Phenolic Compound Isolated from Artocarpus heterophyllus, Suppresses Lipopolysaccharide-Activated Inflammatory Responses in Murine Raw264.7 Macrophages

Research on Intelligent Crack Detection in a Deep-Cut Canal Slope in the Chinese South–North Water Transfer Project

Structure-Based Discovery of a Subtype-Selective Inhibitor Targeting a Transient Receptor Potential Vanilloid Channel

Coptisine, a natural alkaloid from Coptidis Rhizoma, inhibits plasmodium falciparum dihydroorotate dehydrogenase

Activation of orphan receptor GPR132 induces cell differentiation in acute myeloid leukemia

Inhibiting cytoplasmic accumulation of HuR synergizes genotoxic agents in urothelial carcinoma of the bladder

Selective activation of TWIK-related acid-sensitive K + 3 subunit–containing channels is analgesic in rodent models

Research on Soil Moisture Inversion Method for Canal Slope of the Middle Route Project of the South to North Water Transfer Based on GNSS-R and Deep Learning

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