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Targeting Mitochondrial Oxidative Phosphorylation in Glioblastoma Therapy

Neuromolecular medicine, 2022-03, Vol.24 (1), p.18-22

2022

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Pan-cancer adaptive immune resistance as defined by the Tumor Inflammation Signature (TIS): results from The Cancer Genome Atlas (TCGA)

Journal for immunotherapy of cancer, 2018-06, Vol.6 (1), p.63-63, Article 63

2018

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Pantothenate kinase 2 interacts with PINK1 to regulate mitochondrial quality control via acetyl-CoA metabolism

Nature communications, 2022-05, Vol.13 (1), p.2412-2412, Article 2412

2022

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Interplay of RAP2 GTPase and the cytoskeleton in Hippo pathway regulation

The Journal of biological chemistry, 2024-05, Vol.300 (5), p.107257-107257, Article 107257

2024

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Pharmacologic inhibition of protein phosphatase-2A achieves durable immune-mediated antitumor activity when combined with PD-1 blockade

Nature communications, 2018-05, Vol.9 (1), p.2126-15, Article 2126

2018

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CEACAM1 negatively regulates IL-1β production in LPS activated neutrophils by recruiting SHP-1 to a SYK-TLR4-CEACAM1 complex

PLoS pathogens, 2012-04, Vol.8 (4), p.e1002597-e1002597

2012

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Glioma-Immune Cell Crosstalk in Tumor Progression

Cancers, 2024-01, Vol.16 (2), p.308

2024

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1460 PP2Ac deficiency enhances tumor immunogenicity by activating STING-Type I interferon signaling in glioblastoma

Journal for immunotherapy of cancer, 2023-11, Vol.11 (Suppl 1), p.A1623-A1623

2023

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Inhibition of protein phosphatase-2A with LB-100 enhances antitumor immunity against glioblastoma

Journal of neuro-oncology, 2020-06, Vol.148 (2), p.231-244

2020

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LB-100, a novel Protein Phosphatase 2A (PP2A) inhibitor, sensitizes malignant meningioma cells to the therapeutic effects of radiation

Cancer letters, 2018-02, Vol.415, p.217-226

2018

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Neoadjuvant Chemotherapy with Laser Interstitial Thermal Therapy in Central Nervous System Neuroblastoma: Illustrative Case and Literature Review

Brain sciences, 2023-10, Vol.13 (11), p.1515

2023

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G-protein-coupled Receptor Agonist BV8/Prokineticin-2 and STAT3 Protein Form a Feed-forward Loop in Both Normal and Malignant Myeloid Cells

The Journal of biological chemistry, 2013-05, Vol.288 (19), p.13842-13849

2013

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Tumor Angiogenesis Mediated by Myeloid Cells Is Negatively Regulated by CEACAM1

Cancer research (Chicago, Ill.), 2012-05, Vol.72 (9), p.2239-2250

2012

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Immune oncology, immune responsiveness and the theory of everything

Journal for immunotherapy of cancer, 2018-06, Vol.6 (1), p.50-50, Article 50

2018

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Mitochondrial Dysfunction, Macrophage, and Microglia in Brain Cancer

Frontiers in cell and developmental biology, 2021-01, Vol.8, p.620788-620788

2021

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PP2Ac/STRN4 negatively regulates STING-type I IFN signaling in tumor-associated macrophages

The Journal of clinical investigation, 2023-03, Vol.133 (6), p.1-17

2023

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Acoustofluidic assembly of primary tumor-derived organotypic cell clusters for rapid evaluation of cancer immunotherapy

Journal of nanobiotechnology, 2023-02, Vol.21 (1), p.40-40, Article 40

2023

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A combination of protein phosphatase 2A inhibition and checkpoint immunotherapy: a perfect storm

Molecular oncology, 2024-10, Vol.18 (10), p.2333-2337

2024

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CCRG-06. PP2A DEFICIENCY INDUCES CELLULAR SENESCENCE AND SENSITIZES P53 MUTANT TUMORS TO SENOLYTIC THERAPY

Neuro-oncology (Charlottesville, Va.), 2023-11, Vol.25 (Supplement_5), p.v39-v39

2023

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IMMU-42. PP2A-INHIBITION INDUCES STING-TYPE I-MEDIATED IMMUNOLOGIC CELL DEATH IN GBM

Neuro-oncology (Charlottesville, Va.), 2023-11, Vol.25 (Supplement_5), p.v151-v152

2023

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IMMU-47. PROTEIN PHOSPHATASE 2A INHIBITION IN NK CELL THERAPY FOR TREATMENT OF MEDULLOBLASTOMA

Neuro-oncology (Charlottesville, Va.), 2020-11, Vol.22 (Supplement_2), p.ii115-ii115

2020

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NK92 Cells Active Against Human Medulloblastoma and Sensitized by Protein Phosphatase 2A Inhibition In Vitro

Neurosurgery, 2020-12, Vol.67 (Supplement_1)

2020

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Protein Phosphatase 2A Inhibition in Macrophages Enhanced Type I Interferon Production and M1 Polarization

Neurosurgery, 2020-12, Vol.67 (Supplement_1)

2020

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TMIC-65. PP2A/STRN4 NEGATIVELY REGULATES STING-TYPE I IFN SIGNALING IN GLIOMA ASSOCIATED MACROPHAGES THROUGH YAP/TAZ

Neuro-oncology (Charlottesville, Va.), 2023-11, Vol.25 (Supplement_5), p.v293-v293

2023

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494 Enhanced Senescence Phenotype In Human Medulloblastoma via Protein Phosphatase 2A Inhibition and Radiation Therapy

Neurosurgery, 2022-04, Vol.68 (Supplement_1), p.123-124

2022

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Targeting Mitochondrial Oxidative Phosphorylation in Glioblastoma Therapy

Pan-cancer adaptive immune resistance as defined by the Tumor Inflammation Signature (TIS): results from The Cancer Genome Atlas (TCGA)

Pantothenate kinase 2 interacts with PINK1 to regulate mitochondrial quality control via acetyl-CoA metabolism

Interplay of RAP2 GTPase and the cytoskeleton in Hippo pathway regulation

Pharmacologic inhibition of protein phosphatase-2A achieves durable immune-mediated antitumor activity when combined with PD-1 blockade

CEACAM1 negatively regulates IL-1β production in LPS activated neutrophils by recruiting SHP-1 to a SYK-TLR4-CEACAM1 complex

Glioma-Immune Cell Crosstalk in Tumor Progression

1460 PP2Ac deficiency enhances tumor immunogenicity by activating STING-Type I interferon signaling in glioblastoma

Inhibition of protein phosphatase-2A with LB-100 enhances antitumor immunity against glioblastoma

LB-100, a novel Protein Phosphatase 2A (PP2A) inhibitor, sensitizes malignant meningioma cells to the therapeutic effects of radiation

Neoadjuvant Chemotherapy with Laser Interstitial Thermal Therapy in Central Nervous System Neuroblastoma: Illustrative Case and Literature Review

G-protein-coupled Receptor Agonist BV8/Prokineticin-2 and STAT3 Protein Form a Feed-forward Loop in Both Normal and Malignant Myeloid Cells

Tumor Angiogenesis Mediated by Myeloid Cells Is Negatively Regulated by CEACAM1

Immune oncology, immune responsiveness and the theory of everything

Mitochondrial Dysfunction, Macrophage, and Microglia in Brain Cancer

PP2Ac/STRN4 negatively regulates STING-type I IFN signaling in tumor-associated macrophages

Acoustofluidic assembly of primary tumor-derived organotypic cell clusters for rapid evaluation of cancer immunotherapy

A combination of protein phosphatase 2A inhibition and checkpoint immunotherapy: a perfect storm

CCRG-06. PP2A DEFICIENCY INDUCES CELLULAR SENESCENCE AND SENSITIZES P53 MUTANT TUMORS TO SENOLYTIC THERAPY

IMMU-42. PP2A-INHIBITION INDUCES STING-TYPE I-MEDIATED IMMUNOLOGIC CELL DEATH IN GBM

IMMU-47. PROTEIN PHOSPHATASE 2A INHIBITION IN NK CELL THERAPY FOR TREATMENT OF MEDULLOBLASTOMA

NK92 Cells Active Against Human Medulloblastoma and Sensitized by Protein Phosphatase 2A Inhibition In Vitro

Protein Phosphatase 2A Inhibition in Macrophages Enhanced Type I Interferon Production and M1 Polarization

TMIC-65. PP2A/STRN4 NEGATIVELY REGULATES STING-TYPE I IFN SIGNALING IN GLIOMA ASSOCIATED MACROPHAGES THROUGH YAP/TAZ

494 Enhanced Senescence Phenotype In Human Medulloblastoma via Protein Phosphatase 2A Inhibition and Radiation Therapy

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