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FOXO1: a potential target for human diseases

Current drug targets, 2011-08, Vol.12 (9), p.1235-1244

2011

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The Nuclear Protein UHRF2 Is a Direct Target of the Transcription Factor E2F1 in the Induction of Apoptosis

The Journal of biological chemistry, 2013-08, Vol.288 (33), p.23833-23843

2013

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Retinoblastoma tumor cell proliferation is negatively associated with an immune gene expression signature and increased immune cells

Laboratory investigation, 2021-06, Vol.101 (6), p.701-718

2021

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Sensitivity to TOP2 targeting chemotherapeutics is regulated by Oct1 and FILIP1L

PloS one, 2012-08, Vol.7 (8), p.e42921

2012

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Inhibition of Cyclin-Dependent Kinase Phosphorylation of FOXO1 and Prostate Cancer Cell Growth by a Peptide Derived from FOXO1

Neoplasia (New York, N.Y.), 2011-09, Vol.13 (9), p.854-863

2011

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Rb1 and Pten Co-Deletion in Osteoblast Precursor Cells Causes Rapid Lipoma Formation in Mice

PloS one, 2015-08, Vol.10 (8), p.e0136729-e0136729

2015

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Inhibition of ovarian cancer by RGD‐P125A‐endostatin‐Fc fusion proteins

International journal of cancer, 2011-08, Vol.129 (3), p.751-761

2011

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Jab1/CSN5 mediates E2F dependent expression of mitotic and apoptotic but not DNA replication targets

Cell cycle (Georgetown, Tex.), 2011-10, Vol.10 (19), p.3317-3326

2011

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UHRF2 accumulates in early G1-phase after serum stimulation or mitotic exit to extend G1 and total cell cycle length

Cell cycle (Georgetown, Tex.), 2024-03, Vol.23 (5), p.613-627

2024

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UHRF2 accumulates in early G 1 -phase after serum stimulation or mitotic exit to extend G 1 and total cell cycle length

Cell cycle (Georgetown, Tex.), 2024-03, Vol.23 (5), p.613-627

2024

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UHRF2 regulates cell cycle, epigenetics and gene expression to control the timing of retinal progenitor and ganglion cell differentiation

Development (Cambridge), 2022-03, Vol.149 (6)

2022

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Abstract 920: Harnessing multiple mechanisms of action to target Nectin-4 as anti-tumor therapeutics

Cancer research (Chicago, Ill.), 2021-07, Vol.81 (13_Supplement), p.920-920

2021

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Abstract 1869: Novel TNFR2 antibodies to overcome T cell exhaustion and suppressive tumor microenvironment

Cancer research (Chicago, Ill.), 2021-07, Vol.81 (13_Supplement), p.1869-1869

2021

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Abstract A59: Life and death decision by E2F1 depends on Jab1-mediated expression of E2F apoptotic target genes and is counteracted by PI3K activation

Cancer research (Chicago, Ill.), 2011-09, Vol.71 (18_Supplement), p.A59-A59

2011

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Co-deleting Pten with Rb in retinal progenitor cells in mice results in fully penetrant bilateral retinoblastomas

Molecular cancer, 2015-04, Vol.14 (1), p.93-93, Article 93

2015

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Retinoblastoma cells activate the AKT pathway and are vulnerable to the PI3K/mTOR inhibitor NVP-BEZ235

Oncotarget, 2017-06, Vol.8 (24), p.38084-38098

2017

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Abstract 3432: A novel anti-CLDN6-CD137 bispecific antibody (NBL-028) for treating Claudin 6 positive solid tumors

Cancer research (Chicago, Ill.), 2022-06, Vol.82 (12_Supplement), p.3432-3432

2022

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Loss of UHRF2 expression is associated with human neoplasia, promoter hypermethylation, decreased 5-hydroxymethylcytosine, and high proliferative activity

Oncotarget, 2016-11, Vol.7 (46), p.76047-76061

2016

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Retinoblastoma tumor cell proliferation is negatively associated with an immune gene expression signature and increased immune cells

Laboratory investigation, 2021-06, Vol.101 (6), p.701

2021

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Inhibition of Cyclin-Dependent Kinase Phosphorylation of FOXO1 and Prostate Cancer Cell Growth by a Peptide Derived from FOXO11

Neoplasia (New York, N.Y.), 2011-09, Vol.13 (9), p.854-863

2011

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Abstract 1385: Fusion protein containing RGD-endostatin and human Fc of IgG4improves anti-angiogenic and anti-tumor activity

Cancer research (Chicago, Ill.), 2010-04, Vol.70 (8_Supplement), p.1385-1385

2010

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Rb1 and Pten Co-Deletion in Osteoblast Precursor Cells Causes Rapid Lipoma Formation in Mice: e0136729

PloS one, 2015-08, Vol.10 (8)

2015

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Advances in the discovery of exosome inhibitors in cancer

Journal of enzyme inhibition and medicinal chemistry, 2020-01, Vol.35 (1), p.1322-1330

2020

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Targeting loop3 of sclerostin preserves its cardiovascular protective action and promotes bone formation

Nature communications, 2022-07, Vol.13 (1), p.4241-4241, Article 4241

2022

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HIF1α inhibition facilitates Leflunomide-AHR-CRP signaling to attenuate bone erosion in CRP-aberrant rheumatoid arthritis

Nature communications, 2019-10, Vol.10 (1), p.4579-4579, Article 4579

2019

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FOXO1: a potential target for human diseases

The Nuclear Protein UHRF2 Is a Direct Target of the Transcription Factor E2F1 in the Induction of Apoptosis

Retinoblastoma tumor cell proliferation is negatively associated with an immune gene expression signature and increased immune cells

Sensitivity to TOP2 targeting chemotherapeutics is regulated by Oct1 and FILIP1L

Inhibition of Cyclin-Dependent Kinase Phosphorylation of FOXO1 and Prostate Cancer Cell Growth by a Peptide Derived from FOXO1

Rb1 and Pten Co-Deletion in Osteoblast Precursor Cells Causes Rapid Lipoma Formation in Mice

Inhibition of ovarian cancer by RGD‐P125A‐endostatin‐Fc fusion proteins

Jab1/CSN5 mediates E2F dependent expression of mitotic and apoptotic but not DNA replication targets

UHRF2 accumulates in early G1-phase after serum stimulation or mitotic exit to extend G1 and total cell cycle length

UHRF2 accumulates in early G 1 -phase after serum stimulation or mitotic exit to extend G 1 and total cell cycle length

UHRF2 regulates cell cycle, epigenetics and gene expression to control the timing of retinal progenitor and ganglion cell differentiation

Abstract 920: Harnessing multiple mechanisms of action to target Nectin-4 as anti-tumor therapeutics

Abstract 1869: Novel TNFR2 antibodies to overcome T cell exhaustion and suppressive tumor microenvironment

Abstract A59: Life and death decision by E2F1 depends on Jab1-mediated expression of E2F apoptotic target genes and is counteracted by PI3K activation

Co-deleting Pten with Rb in retinal progenitor cells in mice results in fully penetrant bilateral retinoblastomas

Retinoblastoma cells activate the AKT pathway and are vulnerable to the PI3K/mTOR inhibitor NVP-BEZ235

Abstract 3432: A novel anti-CLDN6-CD137 bispecific antibody (NBL-028) for treating Claudin 6 positive solid tumors

Loss of UHRF2 expression is associated with human neoplasia, promoter hypermethylation, decreased 5-hydroxymethylcytosine, and high proliferative activity

Retinoblastoma tumor cell proliferation is negatively associated with an immune gene expression signature and increased immune cells

Inhibition of Cyclin-Dependent Kinase Phosphorylation of FOXO1 and Prostate Cancer Cell Growth by a Peptide Derived from FOXO11

Abstract 1385: Fusion protein containing RGD-endostatin and human Fc of IgG4improves anti-angiogenic and anti-tumor activity

Rb1 and Pten Co-Deletion in Osteoblast Precursor Cells Causes Rapid Lipoma Formation in Mice: e0136729

Advances in the discovery of exosome inhibitors in cancer

Targeting loop3 of sclerostin preserves its cardiovascular protective action and promotes bone formation

HIF1α inhibition facilitates Leflunomide-AHR-CRP signaling to attenuate bone erosion in CRP-aberrant rheumatoid arthritis

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