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Early-onset Amyloid Deposition and Cognitive Deficits in Transgenic Mice Expressing a Double Mutant Form of Amyloid Precursor Protein 695

The Journal of biological chemistry, 2001-06, Vol.276 (24), p.21562-21570

2001

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Interleukin-10 modulates neuronal threshold of vulnerability to ischaemic damage

The European journal of neuroscience, 2000-07, Vol.12 (7), p.2265-2272

2000

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Discovery of Orally Efficacious Tetracyclic Metabotropic Glutamate Receptor 1 (mGluR1) Antagonists for the Treatment of Chronic Pain

Journal of medicinal chemistry, 2007-11, Vol.50 (23), p.5550-5553

2007

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Evaluation of Cannabinoid Receptor 2 and Metabotropic Glutamate Receptor 1 Functional Responses Using a Cell Impedance–Based Technology

Journal of biomolecular screening, 2010-12, Vol.15 (10), p.1238-1247

2010

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Fused tricyclic mGluR1 antagonists for the treatment of neuropathic pain

Bioorganic & medicinal chemistry letters, 2012-02, Vol.22 (4), p.1575-1578

2012

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Age-progressing cognitive impairments and neuropathology in transgenic CRND8 mice

Behavioural brain research, 2005-05, Vol.160 (2), p.344-355

2005

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Tricyclic thienopyridine–pyrimidones/thienopyrimidine–pyrimidones as orally efficacious mGluR1 antagonists for neuropathic pain

Bioorganic & medicinal chemistry letters, 2009-06, Vol.19 (12), p.3199-3203

2009

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Synthesis and SAR development of novel mGluR1 antagonists for the treatment of chronic pain

Bioorganic & medicinal chemistry letters, 2012-12, Vol.22 (23), p.7223-7226

2012

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A-ring modifications on the triazafluorenone core structure and their mGluR1 antagonist properties

Bioorganic & medicinal chemistry letters, 2010-04, Vol.20 (8), p.2474-2477

2010

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Identification of single nucleotide polymorphisms of the human metabotropic glutamate receptor 1 gene and pharmacological characterization of a P993S variant

Biochemical pharmacology, 2009-04, Vol.77 (7), p.1246-1253

2009

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Lack of tolerance to motor stimulant effects of a selective adenosine A(2A) receptor antagonist

European journal of pharmacology, 2000-10, Vol.406 (3), p.345-354

2000

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Long-lasting induction of Notch2 in the hippocampus of kainate-treated adult mice

Neuroreport, 2003-05, Vol.14 (7), p.917-921

2003

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Rapamycin, but not FK506 and GPI-1046, increases neurite outgrowth in PC12 cells by inhibiting cell cycle progression

Neuropharmacology, 2000-09, Vol.39 (10), p.1913-1919

2000

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Long-lasting induction of Notch2 in the hippocampus of kainate-treated adult mice

Neuroreport, 2003-05, Vol.14 (7), p.917-921

2003

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Erratum to “Age-progressing cognitive impairments and neuropathology in transgenic CRND8 mice” [Behav. Brain Res. 160 (2005) 344–355]

Behavioural brain research, 2005-09, Vol.163 (2), p.277-277

2005

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Nonsteroidal Anti‐Inflammatory Drugs Increase Tumor Necrosis Factor Production in the Periphery but Not in the Central Nervous System in Mice and Rats

Journal of neurochemistry, 1998-11, Vol.71 (5), p.2063-2070

1998

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Ecdysone-Based System for Controlled Inducible Expression of Metabotropic Glutamate Receptor Subtypes 2, 5, and 8

Journal of biomolecular screening, 2005-12, Vol.10 (8), p.841-848

2005

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Lack of tolerance to motor stimulant effects of a selective adenosine A2A receptor antagonist

European journal of pharmacology, 2000-10, Vol.406 (3), p.345-354

2000

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Lack of tolerance to motor stimulant effects of a selective adenosine A 2A receptor antagonist

European journal of pharmacology, 2000, Vol.406 (3), p.345-354

2000

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PROLONGED EXPOSURE TO 5′-N-ETHYLCARBOXAMIDOADENOSINE (NECA) DOES NOT AFFECT THE ADENOSINE A2A-MEDIATED VASODILATION IN PORCINE CORONARY ARTERIES

Pharmacological research, 1997-02, Vol.35 (2), p.123-128

1997

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CARDIOPROTECTIVE EFFECTS OF ADENOSINE A1AND A2ARECEPTOR AGONISTS IN THE ISOLATED RAT HEART

Pharmacological research, 1997-01, Vol.35 (1), p.57-64

1997

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HEMODYNAMIC CHANGES DO NOT MEDIATE THE CARDIOPROTECTION INDUCED BY THE A1, ADENOSINE RECEPTOR AGONIST CCPA IN THE RABBIT

Pharmacological research, 1997-01, Vol.35 (1), p.51-55

1997

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Blockade of adenosine A2A receptors by SCH 58261 results in neuroprotective effects in cerebral ischaemia in rats

Neuroreport, 1998-12, Vol.9 (17), p.3955-3958

1998

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PROLONGED EXPOSURE TO 5′-N-ETHYLCARBOXAMIDOADENOSINE (NECA) DOES NOT AFFECT THE ADENOSINE A2A-MEDIATED VASODILATION IN PORCINE CORONARY ARTERIES

Pharmacological research, 1997-02, Vol.35 (2), p.123-128

1997

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Cardiovascular pharmacology of the A2A adenosine receptor antagonist, SCH 58261, in the rat

The Journal of pharmacology and experimental therapeutics, 1998-04, Vol.285 (1), p.9

1998

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Early-onset Amyloid Deposition and Cognitive Deficits in Transgenic Mice Expressing a Double Mutant Form of Amyloid Precursor Protein 695

Interleukin-10 modulates neuronal threshold of vulnerability to ischaemic damage

Discovery of Orally Efficacious Tetracyclic Metabotropic Glutamate Receptor 1 (mGluR1) Antagonists for the Treatment of Chronic Pain

Evaluation of Cannabinoid Receptor 2 and Metabotropic Glutamate Receptor 1 Functional Responses Using a Cell Impedance–Based Technology

Fused tricyclic mGluR1 antagonists for the treatment of neuropathic pain

Age-progressing cognitive impairments and neuropathology in transgenic CRND8 mice

Tricyclic thienopyridine–pyrimidones/thienopyrimidine–pyrimidones as orally efficacious mGluR1 antagonists for neuropathic pain

Synthesis and SAR development of novel mGluR1 antagonists for the treatment of chronic pain

A-ring modifications on the triazafluorenone core structure and their mGluR1 antagonist properties

Identification of single nucleotide polymorphisms of the human metabotropic glutamate receptor 1 gene and pharmacological characterization of a P993S variant

Lack of tolerance to motor stimulant effects of a selective adenosine A(2A) receptor antagonist

Long-lasting induction of Notch2 in the hippocampus of kainate-treated adult mice

Rapamycin, but not FK506 and GPI-1046, increases neurite outgrowth in PC12 cells by inhibiting cell cycle progression

Long-lasting induction of Notch2 in the hippocampus of kainate-treated adult mice

Erratum to “Age-progressing cognitive impairments and neuropathology in transgenic CRND8 mice” [Behav. Brain Res. 160 (2005) 344–355]

Nonsteroidal Anti‐Inflammatory Drugs Increase Tumor Necrosis Factor Production in the Periphery but Not in the Central Nervous System in Mice and Rats

Ecdysone-Based System for Controlled Inducible Expression of Metabotropic Glutamate Receptor Subtypes 2, 5, and 8

Lack of tolerance to motor stimulant effects of a selective adenosine A2A receptor antagonist

Lack of tolerance to motor stimulant effects of a selective adenosine A 2A receptor antagonist

PROLONGED EXPOSURE TO 5′-N-ETHYLCARBOXAMIDOADENOSINE (NECA) DOES NOT AFFECT THE ADENOSINE A2A-MEDIATED VASODILATION IN PORCINE CORONARY ARTERIES

CARDIOPROTECTIVE EFFECTS OF ADENOSINE A1AND A2ARECEPTOR AGONISTS IN THE ISOLATED RAT HEART

HEMODYNAMIC CHANGES DO NOT MEDIATE THE CARDIOPROTECTION INDUCED BY THE A1, ADENOSINE RECEPTOR AGONIST CCPA IN THE RABBIT

Blockade of adenosine A2A receptors by SCH 58261 results in neuroprotective effects in cerebral ischaemia in rats

PROLONGED EXPOSURE TO 5′-N-ETHYLCARBOXAMIDOADENOSINE (NECA) DOES NOT AFFECT THE ADENOSINE A2A-MEDIATED VASODILATION IN PORCINE CORONARY ARTERIES

Cardiovascular pharmacology of the A2A adenosine receptor antagonist, SCH 58261, in the rat

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