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p53 tetramerization: at the center of the dominant-negative effect of mutant p53

Genes & development, 2020-09, Vol.34 (17-18), p.1128-1146

2020

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Limiting the power of p53 through the ubiquitin proteasome pathway

Genes & development, 2014-08, Vol.28 (16), p.1739-1751

2014

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Molecular Pathways: Targeting Mdm2 and Mdm4 in Cancer Therapy

Clinical cancer research, 2013-01, Vol.19 (1), p.34-41

2013

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Attenuating the p53 Pathway in Human Cancers: Many Means to the Same End

Cold Spring Harbor perspectives in medicine, 2016-08, Vol.6 (8), p.a026211

2016

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The Mdm Network and Its Regulation of p53 Activities: A Rheostat of Cancer Risk

Human mutation, 2014-06, Vol.35 (6), p.728-737

2014

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The p53 pathway in hematopoiesis: lessons from mouse models, implications for humans

Blood, 2012-12, Vol.120 (26), p.5118-5127

2012

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Mutant p53: Multiple Mechanisms Define Biologic Activity in Cancer

Frontiers in oncology, 2015-11, Vol.5, p.249-249

2015

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Mammary-specific expression of Trim24 establishes a mouse model of human metaplastic breast cancer

Nature communications, 2021-09, Vol.12 (1), p.5389-15, Article 5389

2021

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Identification of cancer sex-disparity in the functional integrity of p53 and its X chromosome network

Nature communications, 2019-11, Vol.10 (1), p.5385-12, Article 5385

2019

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p53-Mediated Senescence Impairs the Apoptotic Response to Chemotherapy and Clinical Outcome in Breast Cancer

Cancer cell, 2012-06, Vol.21 (6), p.793-806

2012

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MDM2, An Introduction

Molecular cancer research, 2003-12, Vol.1 (14), p.993-1000

2003

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Oncogenic KRAS Recruits an Expansive Transcriptional Network through Mutant p53 to Drive Pancreatic Cancer Metastasis

Cancer discovery, 2021-08, Vol.11 (8), p.2094-2111

2021

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Wnt/ß-catenin-mediated p53 suppression is indispensable for osteogenesis of mesenchymal progenitor cells

Cell death & disease, 2021-05, Vol.12 (6), p.521-521, Article 521

2021

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A spontaneous model of spondyloarthropathies that develops bone loss and pathological bone formation: A process regulated by IL27RA-/- and mutant-p53

PloS one, 2018-03, Vol.13 (3), p.e0193485-e0193485

2018

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Differential Gain-of-Function Activity of Three p53 Hotspot Mutants In Vivo

Cancer research (Chicago, Ill.), 2022-05, Vol.82 (10), p.1926-1936

2022

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A Pin1/Mutant p53 Axis Promotes Aggressiveness in Breast Cancer

Cancer cell, 2011-07, Vol.20 (1), p.79-91

2011

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Heterodimerization of Mdm2 and Mdm4 is critical for regulating p53 activity during embryogenesis but dispensable for p53 and Mdm2 stability

Proceedings of the National Academy of Sciences - PNAS, 2011-07, Vol.108 (29), p.11995-12000

2011

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Somatic Trp53 mutations differentially drive breast cancer and evolution of metastases

Nature communications, 2018-09, Vol.9 (1), p.3953-10, Article 3953

2018

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The histone chaperone function of Daxx is dispensable for embryonic development

Cell death & disease, 2023-08, Vol.14 (8), p.565-9, Article 565

2023

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The Regulation of Cellular Functions by the p53 Protein: Cellular Senescence

Cold Spring Harbor perspectives in medicine, 2017-02, Vol.7 (2), p.a026112

2017

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Transient enhancement of p53 activity protects from radiation-induced gastrointestinal toxicity

Proceedings of the National Academy of Sciences - PNAS, 2019-08, Vol.116 (35), p.17429-17437

2019

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Inhibition of Endothelial p53 Improves Metabolic Abnormalities Related to Dietary Obesity

Cell reports (Cambridge), 2014-06, Vol.7 (5), p.1691-1703

2014

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A Single Nucleotide Polymorphism in the MDM2 Promoter Attenuates the p53 Tumor Suppressor Pathway and Accelerates Tumor Formation in Humans

Cell, 2004-11, Vol.119 (5), p.591-602

2004

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p53 Status in Stromal Fibroblasts Modulates Tumor Growth in an SDF1-Dependent Manner

Cancer research (Chicago, Ill.), 2010-12, Vol.70 (23), p.9650-9658

2010

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Context matters – Daxx and Atrx are not robust tumor suppressors in the murine endocrine pancreas

Disease models & mechanisms, 2022-08, Vol.15 (8)

2022

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p53 tetramerization: at the center of the dominant-negative effect of mutant p53

Limiting the power of p53 through the ubiquitin proteasome pathway

Molecular Pathways: Targeting Mdm2 and Mdm4 in Cancer Therapy

Attenuating the p53 Pathway in Human Cancers: Many Means to the Same End

The Mdm Network and Its Regulation of p53 Activities: A Rheostat of Cancer Risk

The p53 pathway in hematopoiesis: lessons from mouse models, implications for humans

Mutant p53: Multiple Mechanisms Define Biologic Activity in Cancer

Mammary-specific expression of Trim24 establishes a mouse model of human metaplastic breast cancer

Identification of cancer sex-disparity in the functional integrity of p53 and its X chromosome network

p53-Mediated Senescence Impairs the Apoptotic Response to Chemotherapy and Clinical Outcome in Breast Cancer

MDM2, An Introduction

Oncogenic KRAS Recruits an Expansive Transcriptional Network through Mutant p53 to Drive Pancreatic Cancer Metastasis

Wnt/ß-catenin-mediated p53 suppression is indispensable for osteogenesis of mesenchymal progenitor cells

A spontaneous model of spondyloarthropathies that develops bone loss and pathological bone formation: A process regulated by IL27RA-/- and mutant-p53

Differential Gain-of-Function Activity of Three p53 Hotspot Mutants In Vivo

A Pin1/Mutant p53 Axis Promotes Aggressiveness in Breast Cancer

Heterodimerization of Mdm2 and Mdm4 is critical for regulating p53 activity during embryogenesis but dispensable for p53 and Mdm2 stability

Somatic Trp53 mutations differentially drive breast cancer and evolution of metastases

The histone chaperone function of Daxx is dispensable for embryonic development

The Regulation of Cellular Functions by the p53 Protein: Cellular Senescence

Transient enhancement of p53 activity protects from radiation-induced gastrointestinal toxicity

Inhibition of Endothelial p53 Improves Metabolic Abnormalities Related to Dietary Obesity

A Single Nucleotide Polymorphism in the MDM2 Promoter Attenuates the p53 Tumor Suppressor Pathway and Accelerates Tumor Formation in Humans

p53 Status in Stromal Fibroblasts Modulates Tumor Growth in an SDF1-Dependent Manner

Context matters – Daxx and Atrx are not robust tumor suppressors in the murine endocrine pancreas

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