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Major Developments in the Design of Inhibitors along the Kynurenine Pathway

Current medicinal chemistry, 2017-01, Vol.24 (23), p.2471

2017

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Novel thiosemicarbazone iron chelators induce up-regulation and phosphorylation of the metastasis suppressor N-myc down-stream regulated gene 1: a new strategy for the treatment of pancreatic cancer

Molecular pharmacology, 2011-10, Vol.80 (4), p.598-609

2011

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Kynurenine pathway metabolomics predicts and provides mechanistic insight into multiple sclerosis progression

Scientific reports, 2017-02, Vol.7 (1), p.41473-41473, Article 41473

2017

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Evolution and phylogeny of the corticotropin-releasing factor (CRF) family of peptides: Expansion and specialization in the vertebrates

Journal of chemical neuroanatomy, 2013-12, Vol.54, p.50-56

2013

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Brain Co‐Delivery of Temozolomide and Cisplatin for Combinatorial Glioblastoma Chemotherapy

Advanced materials (Weinheim), 2022-08, Vol.34 (33), p.e2203958-n/a

2022

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Correlation between plasma and CSF concentrations of kynurenine pathway metabolites in Alzheimer's disease and relationship to amyloid-β and tau

Neurobiology of aging, 2019-08, Vol.80, p.11-20

2019

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Neuroendocrinology: An Integrated Approach

Lovejoy, David

1. Aufl., 2005

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Behavioral effects of neuropeptides in rodent models of depression and anxiety

Peptides (New York, N.Y. : 1980), 2010-04, Vol.31 (4), p.736-756

2010

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Information Processing in Affective Disorders: Did an Ancient Peptide Regulating Intercellular Metabolism Become Co‐Opted for Noxious Stress Sensing?

BioEssays, 2020-09, Vol.42 (9), p.e2000039-n/a

2020

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Differential kynurenine pathway metabolism in highly metastatic aggressive breast cancer subtypes: beyond IDO1-induced immunosuppression

Breast cancer research : BCR, 2020-10, Vol.22 (1), p.113-14, Article 113

2020

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Antitumor Activity of Metal-Chelating Compound Dp44mT Is Mediated by Formation of a Redox-Active Copper Complex That Accumulates in Lysosomes

Cancer research (Chicago, Ill.), 2011-09, Vol.71 (17), p.5871-5880

2011

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MOLECULAR EVOLUTION OF GPCRS: CRH/CRH receptors

Journal of molecular endocrinology, 2014-06, Vol.52 (3), p.T43-T60

2014

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Role of Teneurin C-Terminal Associated Peptides (TCAP) on Intercellular Adhesion and Communication

Frontiers in neuroscience, 2022-05, Vol.16, p.868541-868541

2022

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Understanding the role of the kynurenine pathway in human breast cancer immunobiology

Oncotarget, 2016-02, Vol.7 (6), p.6506-6520

2016

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The potential for transition metal-mediated neurodegeneration in amyotrophic lateral sclerosis

Frontiers in aging neuroscience, 2014-07, Vol.6, p.173

2014

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Inhibiting the kynurenine pathway in spinal cord injury: Multiple therapeutic potentials?

Neural regeneration research, 2018-12, Vol.13 (12), p.2073-2076

2018

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Biomimetic Dp44mT-nanoparticles selectively induce apoptosis in Cu-loaded glioblastoma resulting in potent growth inhibition

Biomaterials, 2022-10, Vol.289, p.121760-121760, Article 121760

2022

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Stress and reproduction: Controversies and challenges

General and comparative endocrinology, 2011-05, Vol.171 (3), p.253-257

2011

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Brain co‐delivery of first‐line chemotherapy drug and epigenetic bromodomain inhibitor for multidimensional enhanced synergistic glioblastoma therapy

Exploration (Beijing, China), 2022-08, Vol.2 (4), p.20210274-n/a

2022

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Teneurin C-Terminal Associated Peptide (TCAP)-1 and Latrophilin Interaction in HEK293 Cells: Evidence for Modulation of Intercellular Adhesion

Frontiers in endocrinology (Lausanne), 2019-02, Vol.10, p.22-22

2019

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DNA nanoclew templated spherical nucleic acids for siRNA delivery

Chemical communications (Cambridge, England), 2018, Vol.54 (29), p.3609-3612

2018

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Teneurin C-terminal associated peptide (TCAP)-1 attenuates the development and expression of naloxone-precipitated morphine withdrawal in male Swiss Webster mice

Psychopharmacology, 2024-08, Vol.241 (8), p.1565-1575

2024

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The iron chelator, deferasirox, as a novel strategy for cancer treatment: oral activity against human lung tumor xenografts and molecular mechanism of action

Molecular pharmacology, 2013-01, Vol.83 (1), p.179-190

2013

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Plasma neurofilament light chain and amyloid-β are associated with the kynurenine pathway metabolites in preclinical Alzheimer's disease

Journal of neuroinflammation, 2019-10, Vol.16 (1), p.186-186, Article 186

2019

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Novel Second-Generation Di-2-Pyridylketone Thiosemicarbazones Show Synergism with Standard Chemotherapeutics and Demonstrate Potent Activity against Lung Cancer Xenografts after Oral and Intravenous Administration in Vivo

Journal of medicinal chemistry, 2012-08, Vol.55 (16), p.7230-7244

2012

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Major Developments in the Design of Inhibitors along the Kynurenine Pathway

Novel thiosemicarbazone iron chelators induce up-regulation and phosphorylation of the metastasis suppressor N-myc down-stream regulated gene 1: a new strategy for the treatment of pancreatic cancer

Kynurenine pathway metabolomics predicts and provides mechanistic insight into multiple sclerosis progression

Evolution and phylogeny of the corticotropin-releasing factor (CRF) family of peptides: Expansion and specialization in the vertebrates

Brain Co‐Delivery of Temozolomide and Cisplatin for Combinatorial Glioblastoma Chemotherapy

Correlation between plasma and CSF concentrations of kynurenine pathway metabolites in Alzheimer's disease and relationship to amyloid-β and tau

Neuroendocrinology: An Integrated Approach

Behavioral effects of neuropeptides in rodent models of depression and anxiety

Information Processing in Affective Disorders: Did an Ancient Peptide Regulating Intercellular Metabolism Become Co‐Opted for Noxious Stress Sensing?

Differential kynurenine pathway metabolism in highly metastatic aggressive breast cancer subtypes: beyond IDO1-induced immunosuppression

Antitumor Activity of Metal-Chelating Compound Dp44mT Is Mediated by Formation of a Redox-Active Copper Complex That Accumulates in Lysosomes

MOLECULAR EVOLUTION OF GPCRS: CRH/CRH receptors

Role of Teneurin C-Terminal Associated Peptides (TCAP) on Intercellular Adhesion and Communication

Understanding the role of the kynurenine pathway in human breast cancer immunobiology

The potential for transition metal-mediated neurodegeneration in amyotrophic lateral sclerosis

Inhibiting the kynurenine pathway in spinal cord injury: Multiple therapeutic potentials?

Biomimetic Dp44mT-nanoparticles selectively induce apoptosis in Cu-loaded glioblastoma resulting in potent growth inhibition

Stress and reproduction: Controversies and challenges

Brain co‐delivery of first‐line chemotherapy drug and epigenetic bromodomain inhibitor for multidimensional enhanced synergistic glioblastoma therapy

Teneurin C-Terminal Associated Peptide (TCAP)-1 and Latrophilin Interaction in HEK293 Cells: Evidence for Modulation of Intercellular Adhesion

DNA nanoclew templated spherical nucleic acids for siRNA delivery

Teneurin C-terminal associated peptide (TCAP)-1 attenuates the development and expression of naloxone-precipitated morphine withdrawal in male Swiss Webster mice

The iron chelator, deferasirox, as a novel strategy for cancer treatment: oral activity against human lung tumor xenografts and molecular mechanism of action

Plasma neurofilament light chain and amyloid-β are associated with the kynurenine pathway metabolites in preclinical Alzheimer's disease

Novel Second-Generation Di-2-Pyridylketone Thiosemicarbazones Show Synergism with Standard Chemotherapeutics and Demonstrate Potent Activity against Lung Cancer Xenografts after Oral and Intravenous Administration in Vivo

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