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Single-Molecule Fluorescence Experiments Determine Protein Folding Transition Path Times

Science (American Association for the Advancement of Science), 2012-02, Vol.335 (6071), p.981-984

2012

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Effects of an HIV-1 maturation inhibitor on the structure and dynamics of CA-SP1 junction helices in virus-like particles

Proceedings of the National Academy of Sciences - PNAS, 2020-05, Vol.117 (19), p.10286-10293

2020

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Covalent narlaprevir- and boceprevir-derived hybrid inhibitors of SARS-CoV-2 main protease

Nature communications, 2022-04, Vol.13 (1), p.2268-2268, Article 2268

2022

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Three-Color Single-Molecule FRET and Fluorescence Lifetime Analysis of Fast Protein Folding

The journal of physical chemistry. B, 2018-12, Vol.122 (49), p.11702-11720

2018

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Co‐Evolutionary Fitness Landscapes for Sequence Design

Angewandte Chemie International Edition, 2018-05, Vol.57 (20), p.5674-5678

International ed. in English, 2018

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complete influenza hemagglutinin fusion domain adopts a tight helical hairpin arrangement at the lipid:water interface

Proceedings of the National Academy of Sciences - PNAS, 2010-06, Vol.107 (25), p.11341-11346

2010

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Fast three-color single-molecule FRET using statistical inference

Nature communications, 2020-07, Vol.11 (1), p.3336-3336, Article 3336

2020

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Experimental determination of upper bound for transition path times in protein folding from single-molecule photon-by-photon trajectories

Proceedings of the National Academy of Sciences - PNAS, 2009-07, Vol.106 (29), p.11837-11844

2009

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Structural Studies of a Rationally Selected Multi-Drug Resistant HIV-1 Protease Reveal Synergistic Effect of Distal Mutations on Flap Dynamics

PloS one, 2016-12, Vol.11 (12), p.e0168616-e0168616

2016

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Tilted, Uninterrupted, Monomeric HIV‑1 gp41 Transmembrane Helix from Residual Dipolar Couplings

Journal of the American Chemical Society, 2018-01, Vol.140 (1), p.34-37

2018

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Oligomerization of the tetramerization domain of p53 probed by two- and three-color single-molecule FRET

Proceedings of the National Academy of Sciences - PNAS, 2017-08, Vol.114 (33), p.E6812-E6821

2017

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Real-time Exchange of the Lipid-bound Intermediate and Post-fusion States of the HIV-1 gp41 Ectodomain

Journal of molecular biology, 2022-08, Vol.434 (16), p.167683-167683, Article 167683

2022

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Analysis of Fluorescence Lifetime and Energy Transfer Efficiency in Single-Molecule Photon Trajectories of Fast-Folding Proteins

The journal of physical chemistry. B, 2016-02, Vol.120 (4), p.680-699

2016

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Dissociation of the trimeric gp41 ectodomain at the lipid–water interface suggests an active role in HIV-1 Env-mediated membrane fusion

Proceedings of the National Academy of Sciences - PNAS, 2014-03, Vol.111 (9), p.3425-3430

2014

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pH-triggered, activated-state conformations of the influenza hemagglutinin fusion peptide revealed by NMR

Proceedings of the National Academy of Sciences - PNAS, 2012-12, Vol.109 (49), p.19994-19999

2012

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Michaelis-like complex of SARS-CoV-2 main protease visualized by room-temperature X-ray crystallography

IUCrJ, 2021-11, Vol.8 (6), p.973-979

2021

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Characterizing the unfolded states of proteins using single-molecule FRET spectroscopy and molecular simulations

Proceedings of the National Academy of Sciences - PNAS, 2007-01, Vol.104 (5), p.1528-1533

2007

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Evolution of cyclic peptide protease inhibitors

Proceedings of the National Academy of Sciences - PNAS, 2011-07, Vol.108 (27), p.11052-11056

2011

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Pressure-induced structural transition of mature HIV-1 protease from a combined NMR/MD simulation approach

Proteins, structure, function, and bioinformatics, 2015-12, Vol.83 (12), p.2117-2123

2015

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Modulation of the monomer-dimer equilibrium and catalytic activity of SARS-CoV-2 main protease by a transition-state analog inhibitor

Communications biology, 2022-03, Vol.5 (1), p.160-160, Article 160

2022

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Long-Range Electrostatics-Induced Two-Proton Transfer Captured by Neutron Crystallography in an Enzyme Catalytic Site

Angewandte Chemie (International ed.), 2016-04, Vol.55 (16), p.4924-4927

International ed. in English, 2016

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Room Temperature Neutron Crystallography of Drug Resistant HIV‑1 Protease Uncovers Limitations of X‑ray Structural Analysis at 100 K

Journal of medicinal chemistry, 2017-03, Vol.60 (5), p.2018-2025

2017

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Inhibition of autoprocessing of natural variants and multidrug resistant mutant precursors of HIV-1 protease by clinical inhibitors

Proceedings of the National Academy of Sciences - PNAS, 2011-05, Vol.108 (22), p.9072-9077

2011

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Internal Dynamics of the Homotrimeric HIV-1 Viral Coat Protein gp41 on Multiple Time Scales

Angewandte Chemie International Edition, 2013-04, Vol.52 (14), p.3911-3915

International ed. in English, 2013

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Insights into the Conformation of the Membrane Proximal Regions Critical to the Trimerization of the HIV-1 gp41 Ectodomain Bound to Dodecyl Phosphocholine Micelles

PloS one, 2016-08, Vol.11 (8), p.e0160597-e0160597

2016

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Single-Molecule Fluorescence Experiments Determine Protein Folding Transition Path Times

Effects of an HIV-1 maturation inhibitor on the structure and dynamics of CA-SP1 junction helices in virus-like particles

Covalent narlaprevir- and boceprevir-derived hybrid inhibitors of SARS-CoV-2 main protease

Three-Color Single-Molecule FRET and Fluorescence Lifetime Analysis of Fast Protein Folding

Co‐Evolutionary Fitness Landscapes for Sequence Design

complete influenza hemagglutinin fusion domain adopts a tight helical hairpin arrangement at the lipid:water interface

Fast three-color single-molecule FRET using statistical inference

Experimental determination of upper bound for transition path times in protein folding from single-molecule photon-by-photon trajectories

Structural Studies of a Rationally Selected Multi-Drug Resistant HIV-1 Protease Reveal Synergistic Effect of Distal Mutations on Flap Dynamics

Tilted, Uninterrupted, Monomeric HIV‑1 gp41 Transmembrane Helix from Residual Dipolar Couplings

Oligomerization of the tetramerization domain of p53 probed by two- and three-color single-molecule FRET

Real-time Exchange of the Lipid-bound Intermediate and Post-fusion States of the HIV-1 gp41 Ectodomain

Analysis of Fluorescence Lifetime and Energy Transfer Efficiency in Single-Molecule Photon Trajectories of Fast-Folding Proteins

Dissociation of the trimeric gp41 ectodomain at the lipid–water interface suggests an active role in HIV-1 Env-mediated membrane fusion

pH-triggered, activated-state conformations of the influenza hemagglutinin fusion peptide revealed by NMR

Michaelis-like complex of SARS-CoV-2 main protease visualized by room-temperature X-ray crystallography

Characterizing the unfolded states of proteins using single-molecule FRET spectroscopy and molecular simulations

Evolution of cyclic peptide protease inhibitors

Pressure-induced structural transition of mature HIV-1 protease from a combined NMR/MD simulation approach

Modulation of the monomer-dimer equilibrium and catalytic activity of SARS-CoV-2 main protease by a transition-state analog inhibitor

Long-Range Electrostatics-Induced Two-Proton Transfer Captured by Neutron Crystallography in an Enzyme Catalytic Site

Room Temperature Neutron Crystallography of Drug Resistant HIV‑1 Protease Uncovers Limitations of X‑ray Structural Analysis at 100 K

Inhibition of autoprocessing of natural variants and multidrug resistant mutant precursors of HIV-1 protease by clinical inhibitors

Internal Dynamics of the Homotrimeric HIV-1 Viral Coat Protein gp41 on Multiple Time Scales

Insights into the Conformation of the Membrane Proximal Regions Critical to the Trimerization of the HIV-1 gp41 Ectodomain Bound to Dodecyl Phosphocholine Micelles

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