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Glutathione and Glutaredoxin in Redox Regulation and Cell Signaling of the Lens

Antioxidants, 2022-10, Vol.11 (10), p.1973

Lou, Marjorie F

2022

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Redox regulation in the lens

Progress in retinal and eye research, 2003-09, Vol.22 (5), p.657-682

Lou, Marjorie F.

2003

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Glutaredoxin 2 (Grx2) Gene Deletion Induces Early Onset of Age-dependent Cataracts in Mice

The Journal of biological chemistry, 2014-12, Vol.289 (52), p.36125-36139

2014

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Does oxidative stress play any role in diabetic cataract formation? ----Re-evaluation using a thioltransferase gene knockout mouse model

Experimental eye research, 2017-08, Vol.161, p.36-42

2017

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Ultraviolet radiation-induced cataract in mice: the effect of age and the potential biochemical mechanism

Investigative ophthalmology & visual science, 2012-10, Vol.53 (11), p.7276-7285

2012

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Glutaredoxin 2 knockout increases sensitivity to oxidative stress in mouse lens epithelial cells

Free radical biology & medicine, 2011-12, Vol.51 (11), p.2108-2117

2011

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Reactive oxygen species (ROS) are essential mediators in epidermal growth factor (EGF)-stimulated corneal epithelial cell proliferation, adhesion, migration, and wound healing

Experimental eye research, 2009-12, Vol.89 (6), p.876-886

2009

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Failure of Oxysterols Such as Lanosterol to Restore Lens Clarity from Cataracts

Scientific reports, 2019-06, Vol.9 (1), p.8459, Article 8459

2019

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Glutaredoxin-2 Is Required to Control Oxidative Phosphorylation in Cardiac Muscle by Mediating Deglutathionylation Reactions

The Journal of biological chemistry, 2014-05, Vol.289 (21), p.14812-14828

2014

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Roles of the 15-kDa Selenoprotein (Sep15) in Redox Homeostasis and Cataract Development Revealed by the Analysis of Sep 15 Knockout Mice

The Journal of biological chemistry, 2011-09, Vol.286 (38), p.33203-33212

2011

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Loss of thiol repair systems in human cataractous lenses

Investigative ophthalmology & visual science, 2014-12, Vol.56 (1), p.598-605

2014

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Low levels of hydrogen peroxide stimulate corneal epithelial cell adhesion, migration, and wound healing

Investigative ophthalmology & visual science, 2011-03, Vol.52 (3), p.1723-1734

2011

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Effect of age on the thioltransferase (glutaredoxin) and thioredoxin systems in the human lens

Investigative ophthalmology & visual science, 2010-12, Vol.51 (12), p.6598-6604

2010

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Expression and distribution of thiol-regulating enzyme glutaredoxin 2 (GRX2) in porcine ocular tissues

Experimental eye research, 2015-01, Vol.130, p.58-65

2015

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Overexpression of thioredoxin-binding protein 2increases oxidation sensitivity and apoptosis in human lens epithelialcells

Free radical biology & medicine, 2013-04, Vol.57, p.92-104

2013

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Overexpression of thioredoxin-binding protein 2 increases oxidation sensitivity and apoptosis in human lens epithelial cells

Free radical biology & medicine, 2013-04, Vol.57, p.92

2013

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Osmotic stress, not aldose reductase activity, directly induces growth factors and MAPK signaling changes during sugar cataract formation

Experimental eye research, 2012-08, Vol.101, p.36-43

2012

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The Regulation of NADPH Oxidase and Its Association with Cell Proliferation in Human Lens Epithelial Cells

Investigative ophthalmology & visual science, 2009-05, Vol.50 (5), p.2291-2300

2009

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Glutaredoxin 2 prevents H2O2-induced cell apoptosis by protecting complex I activity in the mitochondria

Biochimica et biophysica acta. Bioenergetics, 2010-10, Vol.1797 (10), p.1705-1715

2010

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Regulation of cytosolic phospholipase A2 (cPLA2alpha) and its association with cell proliferation in human lens epithelial cells

Investigative ophthalmology & visual science, 2011-10, Vol.52 (11), p.8231-8240

2011

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Low Levels of Hydrogen Peroxide Stimulate Corneal Epithelial Cell Adhesion, Migration, and Wound Healing

Investigative ophthalmology & visual science, 2011-03, Vol.52 (3), p.1723

2011

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Protective effect of the thioltransferase gene on in vivo UVR-300 nm-induced cataract

Investigative ophthalmology & visual science, 2012-01, Vol.53 (1), p.248

2012

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Control of PDGF-induced reactive oxygen species (ROS) generation and signal transduction in human lens epithelial cells

Molecular vision, 2007-03, Vol.13, p.374-387

2007

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The distribution of cystathionine β-synthase (CBS) in the eye: Implication of the presence of a trans-sulfuration pathway for oxidative stress defense

Experimental eye research, 2006-10, Vol.83 (4), p.817-823

2006

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Thioredoxin induced antioxidant gene expressions in human lens epithelial cells

Experimental eye research, 2006-10, Vol.83 (4), p.783-792

2006

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Glutathione and Glutaredoxin in Redox Regulation and Cell Signaling of the Lens

Redox regulation in the lens

Glutaredoxin 2 (Grx2) Gene Deletion Induces Early Onset of Age-dependent Cataracts in Mice

Does oxidative stress play any role in diabetic cataract formation? ----Re-evaluation using a thioltransferase gene knockout mouse model

Ultraviolet radiation-induced cataract in mice: the effect of age and the potential biochemical mechanism

Glutaredoxin 2 knockout increases sensitivity to oxidative stress in mouse lens epithelial cells

Reactive oxygen species (ROS) are essential mediators in epidermal growth factor (EGF)-stimulated corneal epithelial cell proliferation, adhesion, migration, and wound healing

Failure of Oxysterols Such as Lanosterol to Restore Lens Clarity from Cataracts

Glutaredoxin-2 Is Required to Control Oxidative Phosphorylation in Cardiac Muscle by Mediating Deglutathionylation Reactions

Roles of the 15-kDa Selenoprotein (Sep15) in Redox Homeostasis and Cataract Development Revealed by the Analysis of Sep 15 Knockout Mice

Loss of thiol repair systems in human cataractous lenses

Low levels of hydrogen peroxide stimulate corneal epithelial cell adhesion, migration, and wound healing

Effect of age on the thioltransferase (glutaredoxin) and thioredoxin systems in the human lens

Expression and distribution of thiol-regulating enzyme glutaredoxin 2 (GRX2) in porcine ocular tissues

Overexpression of thioredoxin-binding protein 2increases oxidation sensitivity and apoptosis in human lens epithelialcells

Overexpression of thioredoxin-binding protein 2 increases oxidation sensitivity and apoptosis in human lens epithelial cells

Osmotic stress, not aldose reductase activity, directly induces growth factors and MAPK signaling changes during sugar cataract formation

The Regulation of NADPH Oxidase and Its Association with Cell Proliferation in Human Lens Epithelial Cells

Glutaredoxin 2 prevents H2O2-induced cell apoptosis by protecting complex I activity in the mitochondria

Regulation of cytosolic phospholipase A2 (cPLA2alpha) and its association with cell proliferation in human lens epithelial cells

Low Levels of Hydrogen Peroxide Stimulate Corneal Epithelial Cell Adhesion, Migration, and Wound Healing

Protective effect of the thioltransferase gene on in vivo UVR-300 nm-induced cataract

Control of PDGF-induced reactive oxygen species (ROS) generation and signal transduction in human lens epithelial cells

The distribution of cystathionine β-synthase (CBS) in the eye: Implication of the presence of a trans-sulfuration pathway for oxidative stress defense

Thioredoxin induced antioxidant gene expressions in human lens epithelial cells

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