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A mechanistic overview of translation initiation in eukaryotes

Nature structural & molecular biology, 2012-06, Vol.19 (6), p.568

2012

Volltextzugriff (PDF)

Conformational Differences between Open and Closed States of the Eukaryotic Translation Initiation Complex

Molecular cell, 2015-08, Vol.59 (3), p.399-412

2015

Volltextzugriff (PDF)

Perspective: Sustaining the big-data ecosystem

Nature (London), 2015-11, Vol.527 (7576), p.S16-S17

2015

Volltextzugriff (PDF)

Structural Changes Enable Start Codon Recognition by the Eukaryotic Translation Initiation Complex

Cell, 2014-10, Vol.159 (3), p.597-607

2014

Volltextzugriff (PDF)

Yeast Ded1 promotes 48S translation pre-initiation complex assembly in an mRNA-specific and eIF4F-dependent manner

eLife, 2018-10, Vol.7

2018

Volltextzugriff (PDF)

THE MOLECULAR MECHANICS OF EUKARYOTIC TRANSLATION

Annual review of biochemistry, 2004-01, Vol.73 (1), p.657-704

2004

Volltextzugriff (PDF)

Distinct interactions of eIF4A and eIF4E with RNA helicase Ded1 stimulate translation in vivo

eLife, 2020-05, Vol.9

2020

Volltextzugriff (PDF)

eIF1 discriminates against suboptimal initiation sites to prevent excessive uORF translation genome-wide

RNA (Cambridge), 2020-04, Vol.26 (4), p.419-438

2020

Volltextzugriff (PDF)

Yeast eIF4A enhances recruitment of mRNAs regardless of their structural complexity

eLife, 2017-11, Vol.6

2017

Volltextzugriff (PDF)

Translational initiation factor eIF5 replaces eIF1 on the 40S ribosomal subunit to promote start-codon recognition

eLife, 2018-11, Vol.7

2018

Volltextzugriff (PDF)

Molecular Architecture of a Eukaryotic Translational Initiation Complex

Science (American Association for the Advancement of Science), 2013-11, Vol.342 (6160), p.824-824

2013

Volltextzugriff (PDF)

Transcriptome-wide analysis of the function of Ded1 in translation preinitiation complex assembly in a reconstituted in vitro system

eLife, 2024-04, Vol.13

2024

Volltextzugriff (PDF)

Temperature-dependent regulation of upstream open reading frame translation in S. cerevisiae

BMC biology, 2019-12, Vol.17 (1), p.101-27, Article 101

2019

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The Eukaryotic Translation Initiation Factors eIF1 and eIF1A Induce an Open Conformation of the 40S Ribosome

Molecular cell, 2007-04, Vol.26 (1), p.41-50

2007

Volltextzugriff (PDF)

Coordinated Movements of Eukaryotic Translation Initiation Factors eIF1, eIF1A, and eIF5 Trigger Phosphate Release from eIF2 in Response to Start Codon Recognition by the Ribosomal Preinitiation Complex

The Journal of biological chemistry, 2013-02, Vol.288 (8), p.5316-5329

2013

Volltextzugriff (PDF)

Eukaryotic translation initiation factor 3 plays distinct roles at the mRNA entry and exit channels of the ribosomal preinitiation complex

eLife, 2016-10, Vol.5

2016

Volltextzugriff (PDF)

A Conformational Change in the Eukaryotic Translation Preinitiation Complex and Release of eIF1 Signal Recognition of the Start Codon

Molecular cell, 2005-01, Vol.17 (2), p.265-275

2005

Volltextzugriff (PDF)

Fixing problems with cell lines

Science (American Association for the Advancement of Science), 2014-12, Vol.346 (6216), p.1452-1453

2014

Volltextzugriff (PDF)

eIF1 Controls Multiple Steps in Start Codon Recognition during Eukaryotic Translation Initiation

Journal of molecular biology, 2009-11, Vol.394 (2), p.268-285

2009

Volltextzugriff (PDF)

The mechanism of eukaryotic translation initiation: new insights and challenges

Cold Spring Harbor perspectives in biology, 2012-10, Vol.4 (10), p.a011544-a011544

2012

Volltextzugriff (PDF)

eIF1A residues implicated in cancer stabilize translation preinitiation complexes and favor suboptimal initiation sites in yeast

eLife, 2017-12, Vol.6

2017

Volltextzugriff (PDF)

Kinetic and thermodynamic analysis of the role of start codon/anticodon base pairing during eukaryotic translation initiation

RNA (Cambridge), 2009-01, Vol.15 (1), p.138-152

2009

Volltextzugriff (PDF)

Maximizing the return on taxpayers' investments in fundamental biomedical research

Molecular biology of the cell, 2015-05, Vol.26 (9), p.1578-1582

2015

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Should I Stay or Should I Go? Eukaryotic Translation Initiation Factors 1 and 1A Control Start Codon Recognition

The Journal of biological chemistry, 2008-10, Vol.283 (41), p.27345-27349

2008

Volltextzugriff (PDF)

Dissociation of eIF1 from the 40S ribosomal subunit is a key step in start codon selection in vivo

Genes & development, 2007-05, Vol.21 (10), p.1217-1230

2007

Volltextzugriff (PDF)

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A mechanistic overview of translation initiation in eukaryotes

Conformational Differences between Open and Closed States of the Eukaryotic Translation Initiation Complex

Perspective: Sustaining the big-data ecosystem

Structural Changes Enable Start Codon Recognition by the Eukaryotic Translation Initiation Complex

Yeast Ded1 promotes 48S translation pre-initiation complex assembly in an mRNA-specific and eIF4F-dependent manner

THE MOLECULAR MECHANICS OF EUKARYOTIC TRANSLATION

Distinct interactions of eIF4A and eIF4E with RNA helicase Ded1 stimulate translation in vivo

eIF1 discriminates against suboptimal initiation sites to prevent excessive uORF translation genome-wide

Yeast eIF4A enhances recruitment of mRNAs regardless of their structural complexity

Translational initiation factor eIF5 replaces eIF1 on the 40S ribosomal subunit to promote start-codon recognition

Molecular Architecture of a Eukaryotic Translational Initiation Complex

Transcriptome-wide analysis of the function of Ded1 in translation preinitiation complex assembly in a reconstituted in vitro system

Temperature-dependent regulation of upstream open reading frame translation in S. cerevisiae

The Eukaryotic Translation Initiation Factors eIF1 and eIF1A Induce an Open Conformation of the 40S Ribosome

Coordinated Movements of Eukaryotic Translation Initiation Factors eIF1, eIF1A, and eIF5 Trigger Phosphate Release from eIF2 in Response to Start Codon Recognition by the Ribosomal Preinitiation Complex

Eukaryotic translation initiation factor 3 plays distinct roles at the mRNA entry and exit channels of the ribosomal preinitiation complex

A Conformational Change in the Eukaryotic Translation Preinitiation Complex and Release of eIF1 Signal Recognition of the Start Codon

Fixing problems with cell lines

eIF1 Controls Multiple Steps in Start Codon Recognition during Eukaryotic Translation Initiation

The mechanism of eukaryotic translation initiation: new insights and challenges

eIF1A residues implicated in cancer stabilize translation preinitiation complexes and favor suboptimal initiation sites in yeast

Kinetic and thermodynamic analysis of the role of start codon/anticodon base pairing during eukaryotic translation initiation

Maximizing the return on taxpayers' investments in fundamental biomedical research

Should I Stay or Should I Go? Eukaryotic Translation Initiation Factors 1 and 1A Control Start Codon Recognition

Dissociation of eIF1 from the 40S ribosomal subunit is a key step in start codon selection in vivo

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