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Modeling glioblastoma

eLife, 2024-07, Vol.13

Lorimer, Ian

2024

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Engineered cells as glioblastoma therapeutics

Cancer gene therapy, 2022-02, Vol.29 (2), p.156-166

2022

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PIK3CA, BRAF, and PTEN Status and Benefit from Cetuximab in the Treatment of Advanced Colorectal Cancer―Results from NCIC CTG/AGITG CO.17

Clinical cancer research, 2014-02, Vol.20 (3), p.744-753

2014

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Control of glioblastoma tumorigenesis by feed-forward cytokine signaling

Nature neuroscience, 2016-06, Vol.19 (6), p.798-806

2016

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Modelling the role of the Hsp70/Hsp90 system in the maintenance of protein homeostasis

PloS one, 2011-07, Vol.6 (7), p.e22038-e22038

2011

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Stage-dependent differential expression of microRNAs in colorectal cancer: potential role as markers of metastatic disease

Clinical & experimental metastasis, 2012-02, Vol.29 (2), p.123-132

2012

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Potential roles for efferocytosis in glioblastoma immune evasion

Neuro-oncology advances, 2024-01, Vol.6 (1), p.vdae012-vdae012

Lorimer, Ian A J

2024

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Identification of Rac guanine nucleotide exchange factors promoting Lgl1 phosphorylation in glioblastoma

The Journal of biological chemistry, 2021-11, Vol.297 (5), p.101172-101172, Article 101172

2021

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Induction of premature senescence by hsp90 inhibition in small cell lung cancer

PloS one, 2010-06, Vol.5 (6), p.e11076-e11076

2010

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PREX1 integrates G protein-coupled receptor and phosphoinositide 3-kinase signaling to promote glioblastoma invasion

Oncotarget, 2017-01, Vol.8 (5), p.8559-8573

2017

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Gefitinib Versus Placebo in Completely Resected Non–Small-Cell Lung Cancer: Results of the NCIC CTG BR19 Study

Journal of clinical oncology, 2013-09, Vol.31 (27), p.3320-3326

2013

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Rescue and propagation of fully retargeted oncolytic measles viruses

Nature biotechnology, 2005-02, Vol.23 (2), p.209-214

2005

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Induction of senescence in primary glioblastoma cells by serum and TGFβ

Scientific reports, 2017-05, Vol.7 (1), p.2156-14, Article 2156

2017

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Aberrant Rac pathway signalling in glioblastoma

Small GTPases, 2021-03, Vol.12 (2), p.81-95

Lorimer, Ian AJ

2021

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Atypical PKCι as Target for Glioblastoma Therapy

Current cancer drug targets, 2015-03, Vol.15 (2), p.136-144

Lorimer, Ian

2015

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Erlotinib in Lung Cancer — Molecular and Clinical Predictors of Outcome

The New England journal of medicine, 2005-07, Vol.353 (2), p.133-144

2005

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Engineering PTEN-L for Cell-Mediated Delivery

Molecular therapy. Methods & clinical development, 2018-06, Vol.9, p.12-22

2018

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PTEN loss represses glioblastoma tumor initiating cell differentiation via inactivation of Lgl1

Oncotarget, 2013-08, Vol.4 (8), p.1266-1279

2013

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Avelumab in newly diagnosed glioblastoma

Neuro-oncology advances, 2021-01, Vol.3 (1), p.vdab118-vdab118

2021

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Phase II Study of Lapatinib in Recurrent or Metastatic Epidermal Growth Factor Receptor and/or erbB2 Expressing Adenoid Cystic Carcinoma and Non–Adenoid Cystic Carcinoma Malignant Tumors of the Salivary Glands

Journal of clinical oncology, 2007-09, Vol.25 (25), p.3978-3984

2007

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Coordination of glioblastoma cell motility by PKCι

Molecular cancer, 2010-09, Vol.9 (1), p.233-233, Article 233

2010

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Activation of p38MAPK contributes to expanded polyglutamine-induced cytotoxicity

PloS one, 2008-05, Vol.3 (5), p.e2130

2008

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Retargeting of Adenovirus Vectors through Genetic Fusion of a Single-Chain or Single-Domain Antibody to Capsid Protein IX

Journal of Virology, 2010-10, Vol.84 (19), p.10074-10086

2010

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Loss of PDCD4 contributes to enhanced chemoresistance in Glioblastoma multiforme through de-repression of Bcl-xL translation

Oncotarget, 2013-09, Vol.4 (9), p.1365-1372

2013

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Inhibition of glioblastoma malignancy by Lgl1

Oncotarget, 2014-11, Vol.5 (22), p.11541-11551

2014

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Modeling glioblastoma

Engineered cells as glioblastoma therapeutics

PIK3CA, BRAF, and PTEN Status and Benefit from Cetuximab in the Treatment of Advanced Colorectal Cancer―Results from NCIC CTG/AGITG CO.17

Control of glioblastoma tumorigenesis by feed-forward cytokine signaling

Modelling the role of the Hsp70/Hsp90 system in the maintenance of protein homeostasis

Stage-dependent differential expression of microRNAs in colorectal cancer: potential role as markers of metastatic disease

Potential roles for efferocytosis in glioblastoma immune evasion

Identification of Rac guanine nucleotide exchange factors promoting Lgl1 phosphorylation in glioblastoma

Induction of premature senescence by hsp90 inhibition in small cell lung cancer

PREX1 integrates G protein-coupled receptor and phosphoinositide 3-kinase signaling to promote glioblastoma invasion

Gefitinib Versus Placebo in Completely Resected Non–Small-Cell Lung Cancer: Results of the NCIC CTG BR19 Study

Rescue and propagation of fully retargeted oncolytic measles viruses

Induction of senescence in primary glioblastoma cells by serum and TGFβ

Aberrant Rac pathway signalling in glioblastoma

Atypical PKCι as Target for Glioblastoma Therapy

Erlotinib in Lung Cancer — Molecular and Clinical Predictors of Outcome

Engineering PTEN-L for Cell-Mediated Delivery

PTEN loss represses glioblastoma tumor initiating cell differentiation via inactivation of Lgl1

Avelumab in newly diagnosed glioblastoma

Phase II Study of Lapatinib in Recurrent or Metastatic Epidermal Growth Factor Receptor and/or erbB2 Expressing Adenoid Cystic Carcinoma and Non–Adenoid Cystic Carcinoma Malignant Tumors of the Salivary Glands

Coordination of glioblastoma cell motility by PKCι

Activation of p38MAPK contributes to expanded polyglutamine-induced cytotoxicity

Retargeting of Adenovirus Vectors through Genetic Fusion of a Single-Chain or Single-Domain Antibody to Capsid Protein IX

Loss of PDCD4 contributes to enhanced chemoresistance in Glioblastoma multiforme through de-repression of Bcl-xL translation

Inhibition of glioblastoma malignancy by Lgl1

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