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Targets, models and challenges in osteoarthritis research

Disease models & mechanisms, 2015-01, Vol.8 (1), p.17-30

2015

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Innovation in Targeted Intra-articular Therapies for Osteoarthritis

Drugs (New York, N.Y.), 2023-06, Vol.83 (8), p.649-663

2023

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DOT1L safeguards cartilage homeostasis and protects against osteoarthritis

Nature communications, 2017-06, Vol.8 (1), p.15889-15889, Article 15889

2017

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The balance of tissue repair and remodeling in chronic arthritis

Nature reviews. Rheumatology, 2011-12, Vol.7 (12), p.700-707

Lories, Rik

2011

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Enthesitis: from pathophysiology to treatment

Nature reviews. Rheumatology, 2017-12, Vol.13 (12), p.731-741

2017

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Ankylosing spondylitis: an autoimmune or autoinflammatory disease?

Nature reviews. Rheumatology, 2021-07, Vol.17 (7), p.387-404

2021

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Tendon and ligament mechanical loading in the pathogenesis of inflammatory arthritis

Nature reviews. Rheumatology, 2020-04, Vol.16 (4), p.193-207

2020

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Proof of concept: enthesitis and new bone formation in spondyloarthritis are driven by mechanical strain and stromal cells

Annals of the rheumatic diseases, 2014-02, Vol.73 (2), p.437-445

2014

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Cushioning the cartilage: a canonical Wnt restricting matter

Nature reviews. Rheumatology, 2017-11, Vol.13 (11), p.670-681

2017

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Advances in understanding the pathophysiology of spondyloarthritis

Best practice & research. Clinical rheumatology, 2018-06, Vol.32 (3), p.331-341

Lories, Rik J.

2018

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The bone-cartilage unit in osteoarthritis

Nature reviews. Rheumatology, 2011-01, Vol.7 (1), p.43-49

2011

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Quantification of lung fibrosis and emphysema in mice using automated micro-computed tomography

PloS one, 2012-08, Vol.7 (8), p.e43123

2012

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To Wnt or not to Wnt: the bone and joint health dilemma

Nature reviews. Rheumatology, 2013-06, Vol.9 (6), p.328-339

2013

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Promising targets for therapy of osteoarthritis: a review on the Wnt and TGF-β signalling pathways

Therapeutic Advances in Musculoskeletal Disease, 2021, Vol.13, p.1759720X211006959-1759720X211006959

2021

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Inhibition of KDM7A/B histone demethylases restores H3K79 methylation and protects against osteoarthritis

Annals of the rheumatic diseases, 2023-07, Vol.82 (7), p.963-973

2023

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Review Article: Is Wnt Signaling an Attractive Target for the Treatment of Osteoarthritis?

Rheumatology and therapy., 2020-06, Vol.7 (2), p.259-270

2020

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Pathophysiology of New Bone Formation and Ankylosis in Spondyloarthritis

Rheumatic diseases clinics of North America, 2012-08, Vol.38 (3), p.555-567

2012

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A Notch in the joint that exacerbates osteoarthritis

Nature reviews. Rheumatology, 2018-10, Vol.14 (10), p.563-564

2018

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GDF5 deficiency in mice is associated with instability-driven joint damage, gait and subchondral bone changes

Annals of the rheumatic diseases, 2011-01, Vol.70 (1), p.208-213

2011

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Evolving concepts of new bone formation in axial spondyloarthritis: Insights from animal models and human studies

Best practice & research. Clinical rheumatology, 2017-12, Vol.31 (6), p.877-886

2017

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Microtrauma: no longer to be ignored in spondyloarthritis?

Current opinion in rheumatology, 2016-03, Vol.28 (2), p.176-180

2016

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MAIT cells: not just another brick in the wall

Annals of the rheumatic diseases, 2016-12, Vol.75 (12), p.2057-2059

2016

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The effect of forced exercise on knee joints in Dio2−/− mice: type II iodothyronine deiodinase-deficient mice are less prone to develop OA-like cartilage damage upon excessive mechanical stress

Annals of the rheumatic diseases, 2016-03, Vol.75 (3), p.571-577

2016

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Comorbidities Associated with Psoriatic Arthritis Compared with Non-psoriatic Spondyloarthritis: A Cross-sectional Study

Journal of rheumatology, 2016-02, Vol.43 (2), p.376-382

2016

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Genome-wide association and functional studies identify the DOT1L gene to be involved in cartilage thickness and hip osteoarthritis

Proceedings of the National Academy of Sciences - PNAS, 2012-05, Vol.109 (21), p.8218-8223

2012

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Science & Technology
(172)
Life Sciences & Biomedicine
(159)
Rheumatology
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Humans
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Animals
(69)
Arthritis
(55)
Male
(49)
Mice
(46)
Inflammation
(41)
Osteoarthritis
(39)
Female
(38)
Psoriatic Arthritis
(37)
Cartilage
(30)
Spondyloarthritis
(28)
Ankylosing Spondylitis
(27)
Disease Models, Animal
(27)
Biological And Medical Sciences
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Medical Sciences
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Middle Aged
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Diseases Of The Osteoarticular System
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Targets, models and challenges in osteoarthritis research

Innovation in Targeted Intra-articular Therapies for Osteoarthritis

DOT1L safeguards cartilage homeostasis and protects against osteoarthritis

The balance of tissue repair and remodeling in chronic arthritis

Enthesitis: from pathophysiology to treatment

Ankylosing spondylitis: an autoimmune or autoinflammatory disease?

Tendon and ligament mechanical loading in the pathogenesis of inflammatory arthritis

Proof of concept: enthesitis and new bone formation in spondyloarthritis are driven by mechanical strain and stromal cells

Cushioning the cartilage: a canonical Wnt restricting matter

Advances in understanding the pathophysiology of spondyloarthritis

The bone-cartilage unit in osteoarthritis

Quantification of lung fibrosis and emphysema in mice using automated micro-computed tomography

To Wnt or not to Wnt: the bone and joint health dilemma

Promising targets for therapy of osteoarthritis: a review on the Wnt and TGF-β signalling pathways

Inhibition of KDM7A/B histone demethylases restores H3K79 methylation and protects against osteoarthritis

Review Article: Is Wnt Signaling an Attractive Target for the Treatment of Osteoarthritis?

Pathophysiology of New Bone Formation and Ankylosis in Spondyloarthritis

A Notch in the joint that exacerbates osteoarthritis

GDF5 deficiency in mice is associated with instability-driven joint damage, gait and subchondral bone changes

Evolving concepts of new bone formation in axial spondyloarthritis: Insights from animal models and human studies

Microtrauma: no longer to be ignored in spondyloarthritis?

MAIT cells: not just another brick in the wall

The effect of forced exercise on knee joints in Dio2−/− mice: type II iodothyronine deiodinase-deficient mice are less prone to develop OA-like cartilage damage upon excessive mechanical stress

Comorbidities Associated with Psoriatic Arthritis Compared with Non-psoriatic Spondyloarthritis: A Cross-sectional Study

Genome-wide association and functional studies identify the DOT1L gene to be involved in cartilage thickness and hip osteoarthritis

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